Unicompartmental knee arthroplasty (UKA) has seen a revival of popularity in the last thirty years in the United States. The benefits of a medial UKA over the previous 'gold standard' for knee osteoarthritis, the total knee arthroplasty, include increased postoperative range of motion (ROM), maintenance of natural knee mechanics, faster recovery, similar pain relief and decreased morbidity. Mobile-bearing UKA (MB-UKA) implants have been developed to improve polyethylene wear while maintaining normal knee kinematics. In this review, we will cover indications and contraindications for aN MB-UKA, patient selection, and technical tips and tricks., Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Adolph V. Lombardi, Jr., MD reports a relationship with Zimmer Biomet that includes: consulting or advisory. Adolph V. Lombardi, Jr., MD reports a relationship with Total Joint Orthopedics that includes: consulting or advisory. Adolph V. Lombardi, Jr., MD reports a relationship with Firstkind Ltd that includes: funding grants. Adolph V. Lombardi, Jr., MD reports a relationship with Parvizi Surgical Innovations that includes: equity or stocks and funding grants. Adolph V. Lombardi, Jr., MD reports a relationship with Recovery Rx that includes: funding grants. Adolph V. Lombardi, Jr., MD reports a relationship with SPR Therapeutics Inc that includes: funding grants. Adolph V. Lombardi, Jr., MD reports a relationship with Prescribe Fit that includes: equity or stocks and funding grants. Adolph V. Lombardi, Jr., MD reports a relationship with Smith and Nephew Inc that includes: funding grants. Adolph V. Lombardi, Jr., MD reports a relationship with SI-BONE Inc that includes: funding grants. Adolph V. Lombardi, Jr., MD reports a relationship with JIS Ventures that includes: equity or stocks. Adolph V. Lombardi, Jr., MD reports a relationship with Joint Development Corporation that includes: equity or stocks. Adolph V. Lombardi, Jr., MD reports a relationship with Operation Walk that includes: board membership. Adolph V. Lombardi, Jr., MD reports a relationship with Central Ohio Orthopaedic Management Company that includes: board membership. Adolph V. Lombardi, Jr., MD reports a relationship with Current Concepts in Joint Replacement that includes: board membership. Keith Berend, MD reports a relationship with Medacta USA INC that includes: speaking and lecture fees. Keith Berend, MD reports a relationship with Smith and Nephew Inc that includes: funding grants and speaking and lecture fees. Keith Berend, MD reports a relationship with Zimmer Biomet that includes: funding grants. Keith Berend, MD reports a relationship with Total Joint Orthopedics that includes: funding grants. Keith Berend, MD reports a relationship with Firstkind Ltd that includes: funding grants. Keith Berend, MD reports a relationship with Parvizi Surgical Innovations that includes: equity or stocks and funding grants. Keith Berend, MD reports a relationship with Recovery Rx that includes: funding grants. Keith Berend, MD reports a relationship with Prescribe Fit that includes: equity or stocks and funding grants. Keith Berend, MD reports a relationship with SPR Therapeutics Inc that includes: funding grants. Keith Berend, MD reports a relationship with SI-BONE Inc that includes: funding grants. Keith Berend, MD reports a relationship with JIS Ventures that includes: equity or stocks. Keith Berend, MD reports a relationship with Joint Development Corporation that includes: equity or stocks. Adolph V. Lombardi, Jr., MD reports a relationship with Journal of Bone and Joint Surgery Inc that includes: board membership. Adolph V. Lombardi, Jr., MD reports a relationship with Journal of Arthroplasty that includes: board membership. Adolph V. Lombardi, Jr., MD reports a relationship with Clinical Orthopaedics and Related Research that includes: board membership. Adolph V. Lombardi, Jr., MD reports a relationship with Journal of American Academy of Orthopaedic Surgeons that includes: board membership. Adolph V. Lombardi, Jr., MD reports a relationship with Journal of Orthopaedics and Traumatology that includes: board membership. Adolph V. Lombardi, Jr., MD reports a relationship with Surgical Technology International that includes: board membership. Adolph V. Lombardi, Jr., MD reports a relationship with The Knee that includes: board membership. Adolph V. Lombardi, Jr., MD reports a relationship with The Bone and Joint Journal that includes: board membership. Keith Berend, MD reports a relationship with Journal of Arthroplasty that includes: board membership. Keith Berend, MD reports a relationship with Reconstructive Review that includes: board membership. Adolph V. Lombardi, Jr., MD has patent with royalties paid to Zimmer Biomet. Adolph V. Lombardi, Jr., MD has patent with royalties paid to Innomed. If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 The Author(s). Published by Elsevier Inc. All rights reserved.)