Search

Your search keyword '"van Avesaat, Mark"' showing total 30 results
Start Over Author "van Avesaat, Mark"
30 results on '"van Avesaat, Mark"'

10. Intestinal barrier function in morbid obesity: results of a prospective study on the effect of sleeve gastrectomy

Author

Wilbrink, Jennifer, primary, Bernards, Nienke, additional, Mujagic, Zlatan, additional, van Avesaat, Mark, additional, Pijls, Kirsten, additional, Klaassen, Tim, additional, van Eijk, Hans, additional, Nienhuijs, Simon, additional, Stronkhorst, Arnold, additional, Wilms, Ellen, additional, Troost, Freddy, additional, and Masclee, Ad, additional

Published
2019
Full Text
View/download PDF

14. The effect of an encapsulated nutrient mixture on food intake and satiety : A double-blind randomized cross-over proof of concept study

Author

Alleleyn, Annick M.E., van Avesaat, Mark, Ripken, Dina, Bleiel, Sinéad B., Keszthelyi, Daniel, Wilms, Ellen, Troost, Freddy J., Hendriks, Henk F.J., Masclee, Adrian A.M., Alleleyn, Annick M.E., van Avesaat, Mark, Ripken, Dina, Bleiel, Sinéad B., Keszthelyi, Daniel, Wilms, Ellen, Troost, Freddy J., Hendriks, Henk F.J., and Masclee, Adrian A.M.

Abstract

Activation of the intestinal brake by infusing nutrients into the distal small intestine with catheters inhibits food intake and enhances satiety. Encapsulation of macronutrients, which protects against digestion in the proximal gastrointestinal tract, can be a non-invasive alternative to activate this brake. In this study, we investigate the effect of oral ingestion of an encapsulated casein and sucrose mixture (active) targeting the distal small intestine versus a control product designed to be released in the stomach on food intake, satiety, and plasma glucose concentrations. Fifty-nine volunteers received the active and control product on two separate test days. Food intake was determined during an ad libitum meal 90 min after ingestion of the test product. Visual analogue scale scores for satiety and blood samples for glucose analysis were collected at regular intervals. Ingestion of the active product decreased food intake compared to the control product (655 kcal compared with 699 kcal, respectively, p < 0.05). The area under the curve (AUC) for hunger was decreased (p < 0.05) and AUC for satiety was increased (p < 0.01) after ingestion of the active product compared to the control product. Ingestion of an encapsulated protein-carbohydrate mixture resulted in inhibition of food intake compared to a non-encapsulated control product.

Published
2018

18. 396 Open, Prospective Study to Evaluate the Safety and Preliminary Effectiveness of the ACE™ Stapler for the Treatment of Obesity

Author

Biertho, Laurent, primary, Lebel, Stefane, additional, Hould, Frederic, additional, Marceau, Simon, additional, Horgan, Santiago, additional, Omelanczuk, Pablo, additional, Ongay, Rodrigo, additional, Sanchez, M., additional, Pampillon, Andrea N., additional, Penutto, C., additional, Lasagini, V., additional, Omelanczuk, Sonia, additional, Grigaites, A., additional, Buxhoeveden, R., additional, Gorodner, V., additional, Santo, Erwin, additional, Fishman, Sigal, additional, Bouvy, Nicole D., additional, Paulus, G., additional, van Rijn, Selwyn, additional, van Avesaat, Mark, additional, Boerlage, Thomas, additional, Mathus-Vliegen, E.M., additional, Fockens, Paul, additional, and Biron, Simon, additional

Published
2016
Full Text
View/download PDF

20. Response

Author

Paulus, Givan F., primary, van Avesaat, Mark, additional, Mathus-Vliegen, Elisabeth M.H., additional, Bouvy, Nicole D., additional, and Fockens, Paul, additional

Published
2015
Full Text
View/download PDF

23. Cross-Species Comparison of Genes Related to Nutrient Sensing Mechanisms Expressed along the Intestine

Author

van der Wielen, Nikkie, primary, van Avesaat, Mark, additional, de Wit, Nicole J. W., additional, Vogels, Jack T. W. E., additional, Troost, Freddy, additional, Masclee, Ad, additional, Koopmans, Sietse-Jan, additional, van der Meulen, Jan, additional, Boekschoten, Mark V., additional, Müller, Michael, additional, Hendriks, Henk F. J., additional, Witkamp, Renger F., additional, and Meijerink, Jocelijn, additional

Published
2014
Full Text
View/download PDF

30. Changes in gastrointestinal motility and gut hormone secretion after Roux-en-Y gastric bypass and sleeve gastrectomy for individuals with severe obesity.

Author

Wilbrink JA, van Avesaat M, Nienhuijs SW, Stronkhorst A, and Masclee AAM

Abstract

Background: Bariatric surgery is very effective in long-term weight management. The present study was undertaken to investigate the short-term effects of sleeve gastrectomy (SG) and of Roux-en-Y gastric bypass (RYGB) on (a) gastrointestinal (GI) motility, that is gastric emptying and oro-cecal transit time and (b) secretion of regulatory gut peptides and (c) their interrelationship., Methods: Prospective single-centre study in which we assessed gastric emptying, oro-cecal transit time and gut peptide release in 28 severely obese individuals before and 2, respectively, 12 months after bariatric surgery (either SG or RYGB). Plasma PYY, GLP-1, ghrelin, insulin and glucose levels were measured fasting and after intake of a solid standard 459 kcal meal at each occasion. Gastric emptying was measured by 13 C octanoic acid breath testing, and oro-cecal transit time was measured by lactulose H 2 breath testing. Satiation was measured using VAS scores., Results: After both RYGB and SG gastric emptying become significantly accelerated, and postprandial release of the distal gut peptides GLP-1 and PYY becomes significantly increased, pointing to ileal brake activation. Oro-cecal transit time becomes significantly accelerated after SG but not after RYGB. No significant correlations were observed between changes in distal gut peptide release, changes in GI motility and clinical parameters., Conclusion: Both SG and RYGB resulted in significant weight loss and significantly affected GI motility and PYY and GLP-1 secretion. Subtle differences between both procedures were found in effect on oro-cecal transit time and patterns of peptide secretion., (© 2024 The Author(s). Clinical Obesity published by John Wiley & Sons Ltd on behalf of World Obesity Federation.)

Published
2024
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results