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2. Prognostic value of histopathologic traits independent of stromal tumor-infiltrating lymphocyte levels in chemotherapy-naïve patients with triple-negative breast cancer

Author

de Boo, L.W., Jóźwiak, K., Ter Hoeve, N.D., van Diest, P.J., Opdam, M., Wang, Y., Schmidt, M.K., de Jong, V., Kleiterp, S., Cornelissen, S., Baars, D., Koornstra, R.H.T., Kerver, E.D., van Dalen, T., Bins, A.D., Beeker, A., van den Heiligenberg, S.M., de Jong, P.C., Bakker, S.D., Rietbroek, R.C., Konings, I.R., Blankenburgh, R., Bijlsma, R.M., Imholz, A.L.T., Stathonikos, N., Vreuls, W., Sanders, J., Rosenberg, E.H., Koop, E.A., Varga, Z., van Deurzen, C.H.M., Mooyaart, A.L., Córdoba, A., Groen, E., Bart, J., Willems, S.M., Zolota, V., Wesseling, J., Sapino, A., Chmielik, E., Ryska, A., Broeks, A., Voogd, A.C., van der Wall, E., Siesling, S., Salgado, R., Dackus, G.M.H.E., Hauptmann, M., Kok, M., and Linn, S.C.

Published
2024
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6. Limiting systemic endocrine overtreatment in postmenopausal breast cancer patients with an ultralow classification of the 70-gene signature

Author

Opdam, M., van der Noort, V., Kleijn, M., Glas, A., Mandjes, I., Kleiterp, S., Hilbers, F. S., Kruger, D. T., Bins, A. D., de Jong, P. C., Schiphorst, P. P. J. B. M., van Dalen, T., Flameling, B., Rietbroek, R. C., Beeker, A., van den Heiligenberg, S. M., Bakker, S. D., Wymenga, A. N. M., Oving, I. M., Bijlsma, R. M., van Diest, P. J., Vermorken, J. B., van Tinteren, H., and Linn, S. C.

Published
2022
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7. In-hospital Delay of Appendectomy in Acute, Complicated Appendicitis

Author

Bolmers, M.D.M., de Jonge, J., Bom, W.J., van Rossem, C.C., van Geloven, A.A.W., Bemelman, W.A., Van Acker, G.J., Akkermans, B., Akkersdijk, G.J., Algie, G.D., Allema, J.H., Andeweg, C.S., Appeldoorn, N., van Baal, J.G., Bakker, C.M.den, Bartels, S.A., van den Berg, C., Boekestijn, B., Boer, F.C.den, Boerma, D., van den Boom, A.L., Boute, M.C., Bouwense, S.A., Bransen, J., van Brussel, F.A., Busch, O.R., de Castro, S.M., Cense, H.A., Croese, C., van dalen, T., Dawson, I., van Dessel, E., Dettmers, R., Dhar, N., Dohmen, F.Y., van Dongen, K.W., van Duijvendijk, P., Dulfer, R.R., Dwars, B.J., Eerenberg, J.P., van der Elst, M., van den Ende, E., Fassaert, L.M., Fikkers, J.T., Foppen, J.W., Furnee, E.J., Garssen, F.P., Gerhards, M.F., van Goor, H., de Graaf, J.S., Graat, L.J., Grootr, J., van der Ham, A.C., Hamming, J.F., Hamminga, J.T., van der Harst, E., Heemskerk, J., Heijne, A., Heikens, J.T., Heineman, E., Hertogs, R., van Heurn, E., van den Hil, L.C., Hooftwijk, A.G., Hulsker, C.C., Hunen, D.R., Ibelings, M.S., Klaase, J.M., Klicks, R., Knaapen, L., Kortekaas, R.T., Kruyt, F., Kwant, S., Lases, S.S., Lettinga, T., Loupatty, A., Matthijsen, R.A., Minnee, R.C., Mirck, B., Mitalas, L., Moes, D., Moorman, A.M., Nieuwenhuijs, V.B., Nieuwenhuizen, G.A., Nijk, P.D., Omloo, J.M., Ottenhof, A.G., Palamba, H.W., van der Peet, D.L., Pereboom, I.T., Plaisier, P.W., van der Ploeg, A.P., Raber, M.H., Reijen, M.M., Rijna, H., Rosman, C., Roumen, R.M., Scmitz, R.F., Schouten van der Velden, A.P., Scheurs, W.H., Sigterman, T.A., Smeets, H.J., Sonnevled, D.J., Sosef, M.N., Spoor, S.F., Stassen, L.P., van Steensel, L., Stortelder, E., Straatman, J., van Susante, H.J., Suykerbuyk de Hoog, D.E., Terwisscha van Scheltinga, C., Toorenvliet, B.R., Verbeek, P.C., Verseveld, M., Volders, J.H., Vriens, M.R., Vriens, P.W., Vrouenraets, B.C., van de wall, B.J., Wegdam, J.A., Westerduin, E., Wever, J.J., Wijfels, N.A., Wijnhoven, B.P., Winkel, T.A., van der Zee, D.C., Zeillemaker, A.M., and Zietse, C.

Published
2022
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8. Effects of structured involvement of the primary care team versus standard care after a cancer diagnosis on patient satisfaction and healthcare use: the GRIP randomised controlled trial

Author

Perfors, I. A. A., Helsper, C. W., Noteboom, E. A., Visserman, E. A., van Dorst, E. B. L., van Dalen, T., Verhagen, M. A. M. T., Witkamp, A. J., Koelemij, R., Flinterman, A. E., Pruissen-Peeters, K. A. B. M., Schramel, F. M. N. H., van Rens, M. T. M., Ernst, M. F., Moons, L. M. G., van der Wall, E., de Wit, N. J., and May, A. M.

Published
2022
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9. Discrepancies between Intraoperative and Histological Evaluation of the Appendix in Acute Appendicitis

Author

Bolmers, Matthijs D.M., de Jonge, Joske, van Rossem, Charles C., van Geloven, Anna A.W., Bemelman, Willem A., Van Acker, G.J., Akkermans, B., Akkersdijk, G.J., Algie, G.D., Allema, J.H., Andeweg, C.S., Appeldoorn, N., van Baal, J.G., den Bakker, C.M., Bartels, S.A., van den Berg, C., Boekestijn, B., den Boer, F.C., Boerma, D., van den Boom, A.L., Boute, M.C., Bouwense, S.A., Bransen, J., van Brussel, F.A., Busch, O.R., de Castro, S.M., Cense, H.A., Croese, C., van dalen, T., Dawson, I., van Dessel, E., Dettmers, R., Dhar, N., Dohmen, F.Y., van Dongen, K.W., van Duijvendijk, P., Dulfer, R.R., Dwars, B.J., Eerenberg, J.P., van der Elst, M., van den Ende, E., Fassaert, L.M., Fikkers, J.T., Foppen, J.W., Furnee, E.J., Garssen, F.P., Gerhards, M.F., van Goor, H., de Graaf, J.S., Graat, L.J., Grootr, J., van der Ham, A.C., Hamming, J.F., Hamminga, J.T., van der Harst, E., Heemskerk, J., Heijne, A., Heikens, J.T., Heineman, E., Hertogs, R., van Heurn, E., van den Hil, L.C., Hooftwijk, A.G., Hulsker, C.C., Hunen, D.R., Ibelings, M.S., Klaase, J.M., Klicks, R., Knaapen, L., Kortekaas, R.T., Kruyt, F., Kwant, S., Lases, S.S., Lettinga, T., Loupatty, A., Matthijsen, R.A., Minnee, R.C., Mirck, B., Mitalas, L., Moes, D., Moorman, A.M., Nieuwenhuijs, V.B., Nieuwenhuizen, G.A., Nijk, P.D., Omloo, J.M., Ottenhof, A.G., Palamba, H.W., van der Peet, D.L., Pereboom, I.T., Plaisier, P.W., van der Ploeg, A.P., Raber, M.H., Reijen, M.M., Rijna, H., Rosman, C., Roumen, R.M., Scmitz, R.F., van der Velden, A.P.Schouten, Scheurs, W.H., Sigterman, T.A., Smeets, H.J., Sonnevled, D.J., Sosef, M.N., Spoor, S.F., Stassen, L.P., van Steensel, L., Stortelder, E., Straatman, J., van Susante, H.J., de Hoog, D.E.Suykerbuyk, Te van Scheltinga, C.rwisscha, Toorenvliet, B.R., Verbeek, P.C., Verseveld, M., Volders, J.H., Vriens, M.R., Vriens, P.W., Vrouenraets, B.C., van de wall, B.J., Wegdam, J.A., Westerduin, E., Wever, J.J., Wijfels, N.A., Wijnhoven, B.P., Winkel, T.A., van der Zee, D.C., Zeillemaker, A.M., and Zietse, C.

Published
2020
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10. Health-related quality of life (HRQoL) after different axillary treatments in women with breast cancer:a 1-year longitudinal cohort study

Author

Vrancken Peeters, N. J.M.C., Kaplan, Z. L.R., Clarijs, M. E., Mureau, M. A.M., Verhoef, C., van Dalen, T., Husson, O., Koppert, L. B., Vrancken Peeters, N. J.M.C., Kaplan, Z. L.R., Clarijs, M. E., Mureau, M. A.M., Verhoef, C., van Dalen, T., Husson, O., and Koppert, L. B.

Abstract

Purpose: As life expectancy continues to rise, post-treatment health-related quality of life (HRQoL) of breast cancer patients becomes increasingly important. This study examined the one-year longitudinal relation between axillary treatments and physical, psychosocial, and sexual wellbeing and arm symptoms. Methods: Women diagnosed with breast cancer who received different axillary treatments being axilla preserving surgery (APS) with or without axillary radiotherapy or full axillary lymph node dissection (ALND) with or without axillary radiotherapy were included. HRQoL was assessed at baseline, 6- and 12-months postoperatively using the BREAST-Q and the European Organization for Research and Treatment of Cancer QoL Questionnaire Breast Cancer Module (EORTC QLQ-BR23). Mixed regression models were constructed to assess the impact of axillary treatment on HRQoL. HRQoL at baseline was compared to HRQoL at 6- and at 12-months postoperatively. Results: In total, 552 patients were included in the mixed regressions models. Except for ALND with axillary radiotherapy, no significant differences in physical and psychosocial wellbeing were found. Physical wellbeing decreased significantly between baseline and 6- and 12-months postoperatively (p < 0.001, p = 0.035) and psychosocial wellbeing decreased significantly between baseline and 12 months postoperatively (p = 0.028) for ALND with axillary radiotherapy compared to APS alone. Arm symptoms increased significantly between baseline and 6 months and between baseline and 12 months postoperatively for APS with radiotherapy (12.71, 13.73) and for ALND with radiotherapy (13.93, 16.14), with the lowest increase in arm symptoms for ALND without radiotherapy (6.85, 7.66), compared to APS alone (p < 0.05). Conclusion: Physical and psychosocial wellbeing decreased significantly for ALND with radiotherapy compared to APS alone. Shared decision making a

Published
2024

11. Quality assurance of radiation therapy after breast-conserving surgery among patients in the BOOG 2013-08 trial

Author

Wintraecken, V. M., Boersma, L. J., van Roozendaal, L. M., de Vries, J., van Kuijk, S. M.J., Vane, M. L.G., van Dalen, T., van der Hage, J. A., Strobbe, L. J.A., Linn, S. C., Lobbes, M. B.I., Poortmans, P. M.P., Tjan-Heijnen, V. C.G., van de Vijver, K. K.B.T., Westenberg, A. H., de Wilt, J. H.W., Smidt, M. L., Simons, J. M., Wintraecken, V. M., Boersma, L. J., van Roozendaal, L. M., de Vries, J., van Kuijk, S. M.J., Vane, M. L.G., van Dalen, T., van der Hage, J. A., Strobbe, L. J.A., Linn, S. C., Lobbes, M. B.I., Poortmans, P. M.P., Tjan-Heijnen, V. C.G., van de Vijver, K. K.B.T., Westenberg, A. H., de Wilt, J. H.W., Smidt, M. L., and Simons, J. M.

Abstract

Background and purpose: In the BOOG 2013-08 trial (NCT02271828), cT1-2N0 breast cancer patients were randomized between breast conserving surgery with or without sentinel lymph node biopsy (SLNB) followed by whole breast radiotherapy (WBRT). While awaiting primary endpoint results (axillary recurrence rate), this study aims to perform a quality assurance analysis on protocol adherence and (incidental) axillary radiation therapy (RT) dose. Materials and methods: Patients were enrolled between 2015 and 2022. Data on prescribed RT and (in 25% of included patients) planning target volumes (PTV) parameters were recorded for axillary levels I-IV and compared between treatment arms. Multivariable linear regression analysis was performed to determine prognostic variables for incidental axillary RT dose. Results: 1,439/1,461 included patients (98.5%) were treated according to protocol and 87 patients (5.9%) received regional RT (SLNB 10.9%, no-SLNB 1.5 %). In 326 patients included in the subgroup analysis, the mean incidental PTV dose at axilla level I was 59.5% of the prescribed breast RT dose. In 5 patients (1.5%) the mean PTV dose at level I was ≥95% of the prescribed breast dose. No statistically or clinically significant differences regarding incidental axillary RT dose were found between treatment arms. Tumour bed boost (yes/no) was associated with a higher incidental mean dose in level I (R2 = 0.035, F(6, 263) = 1.532, p 0.168). Conclusion: The results indicate that RT-protocol adherence was high, and that incidental axillary RT dose was low in the BOOG 2013-08 trial. Potential differences between treatmentarms regarding the primary endpoint can thus not be attributed to different axillary radiation doses.

Published
2024

12. Prognostic value of histopathologic traits independent of stromal tumor-infiltrating lymphocyte levels in chemotherapy-naïve patients with triple-negative breast cancer

Author

de Boo, L W, Jóźwiak, K; https://orcid.org/0000-0002-9614-6586, Ter Hoeve, N D, van Diest, P J; https://orcid.org/0000-0003-0658-2745, Opdam, M; https://orcid.org/0000-0001-5832-6386, Wang, Y; https://orcid.org/0000-0002-1482-7039, Schmidt, M K; https://orcid.org/0000-0002-2228-429X, de Jong, V, Kleiterp, S, Cornelissen, S, Baars, D, Koornstra, R H T, Kerver, E D; https://orcid.org/0009-0004-6456-4857, van Dalen, T, Bins, A D, Beeker, A; https://orcid.org/0000-0003-4133-769X, van den Heiligenberg, S M, de Jong, P C, Bakker, S D; https://orcid.org/0000-0003-3936-4648, Rietbroek, R C, Konings, I R, Blankenburgh, R, Bijlsma, R M; https://orcid.org/0000-0003-0980-6652, Imholz, A L T, Stathonikos, N, Vreuls, W; https://orcid.org/0000-0001-6661-6017, Sanders, J, Rosenberg, E H; https://orcid.org/0000-0002-3859-6941, Koop, E A, Varga, Z; https://orcid.org/0000-0002-2855-983X, et al, de Boo, L W, Jóźwiak, K; https://orcid.org/0000-0002-9614-6586, Ter Hoeve, N D, van Diest, P J; https://orcid.org/0000-0003-0658-2745, Opdam, M; https://orcid.org/0000-0001-5832-6386, Wang, Y; https://orcid.org/0000-0002-1482-7039, Schmidt, M K; https://orcid.org/0000-0002-2228-429X, de Jong, V, Kleiterp, S, Cornelissen, S, Baars, D, Koornstra, R H T, Kerver, E D; https://orcid.org/0009-0004-6456-4857, van Dalen, T, Bins, A D, Beeker, A; https://orcid.org/0000-0003-4133-769X, van den Heiligenberg, S M, de Jong, P C, Bakker, S D; https://orcid.org/0000-0003-3936-4648, Rietbroek, R C, Konings, I R, Blankenburgh, R, Bijlsma, R M; https://orcid.org/0000-0003-0980-6652, Imholz, A L T, Stathonikos, N, Vreuls, W; https://orcid.org/0000-0001-6661-6017, Sanders, J, Rosenberg, E H; https://orcid.org/0000-0002-3859-6941, Koop, E A, Varga, Z; https://orcid.org/0000-0002-2855-983X, and et al

Published
2024

13. Prognostic value of histopathologic traits independent of stromal tumor-infiltrating lymphocyte levels in chemotherapy-naïve patients with triple-negative breast cancer

Author

Pathologie, Cancer, MMB opleiding Arts microbioloog, Neurogenetica, MS CGO, Public Health Practice, Affectieve & Psychotische Med., MS Medische Oncologie, Pathologie Support, Pathologie Pathologen staf, MS Reumatologie/Immunologie/Infectie, Speerpunt Cancer, KVO Docenten, de Boo, L W, Jóźwiak, K, Ter Hoeve, N D, van Diest, P J, Opdam, M, Wang, Y, Schmidt, M K, de Jong, V, Kleiterp, S, Cornelissen, S, Baars, D, Koornstra, R H T, Kerver, E D, van Dalen, T, Bins, A D, Beeker, A, van den Heiligenberg, S M, de Jong, P C, Bakker, S D, Rietbroek, R C, Konings, I R, Blankenburgh, R, Bijlsma, R M, Imholz, A L T, Stathonikos, N, Vreuls, W, Sanders, J, Rosenberg, E H, Koop, E A, Varga, Z, van Deurzen, C H M, Mooyaart, A L, Córdoba, A, Groen, E, Bart, J, Willems, S M, Zolota, V, Wesseling, J, Sapino, A, Chmielik, E, Ryska, A, Broeks, A, Voogd, A C, van der Wall, E, Siesling, S, Salgado, R, Dackus, G M H E, Hauptmann, M, Kok, M, Linn, S C, Pathologie, Cancer, MMB opleiding Arts microbioloog, Neurogenetica, MS CGO, Public Health Practice, Affectieve & Psychotische Med., MS Medische Oncologie, Pathologie Support, Pathologie Pathologen staf, MS Reumatologie/Immunologie/Infectie, Speerpunt Cancer, KVO Docenten, de Boo, L W, Jóźwiak, K, Ter Hoeve, N D, van Diest, P J, Opdam, M, Wang, Y, Schmidt, M K, de Jong, V, Kleiterp, S, Cornelissen, S, Baars, D, Koornstra, R H T, Kerver, E D, van Dalen, T, Bins, A D, Beeker, A, van den Heiligenberg, S M, de Jong, P C, Bakker, S D, Rietbroek, R C, Konings, I R, Blankenburgh, R, Bijlsma, R M, Imholz, A L T, Stathonikos, N, Vreuls, W, Sanders, J, Rosenberg, E H, Koop, E A, Varga, Z, van Deurzen, C H M, Mooyaart, A L, Córdoba, A, Groen, E, Bart, J, Willems, S M, Zolota, V, Wesseling, J, Sapino, A, Chmielik, E, Ryska, A, Broeks, A, Voogd, A C, van der Wall, E, Siesling, S, Salgado, R, Dackus, G M H E, Hauptmann, M, Kok, M, and Linn, S C

Published
2024

14. Prognostic value of histopathologic traits independent of stromal tumor-infiltrating lymphocyte levels in chemotherapy-naïve patients with triple-negative breast cancer

Author

de Boo, L. W., Jóźwiak, K., Ter Hoeve, N. D., van Diest, P. J., Opdam, M., Wang, Y., Schmidt, M. K., de Jong, V., Kleiterp, S., Cornelissen, S., Baars, D., Koornstra, R. H.T., Kerver, E. D., van Dalen, T., Bins, A. D., Beeker, A., van den Heiligenberg, S. M., de Jong, P. C., Bakker, S. D., Rietbroek, R. C., Konings, I. R., Blankenburgh, R., Bijlsma, R. M., Imholz, A. L.T., Stathonikos, N., Vreuls, W., Sanders, J., Rosenberg, E. H., Koop, E. A., Varga, Z., van Deurzen, C. H.M., Mooyaart, A. L., Córdoba, A., Groen, E., Bart, J., Willems, S. M., Zolota, V., Wesseling, J., Sapino, A., Chmielik, E., Ryska, A., Broeks, A., Voogd, A. C., van der Wall, E., Siesling, S., Salgado, R., Dackus, G. M.H.E., Hauptmann, M., Kok, M., Linn, S. C., de Boo, L. W., Jóźwiak, K., Ter Hoeve, N. D., van Diest, P. J., Opdam, M., Wang, Y., Schmidt, M. K., de Jong, V., Kleiterp, S., Cornelissen, S., Baars, D., Koornstra, R. H.T., Kerver, E. D., van Dalen, T., Bins, A. D., Beeker, A., van den Heiligenberg, S. M., de Jong, P. C., Bakker, S. D., Rietbroek, R. C., Konings, I. R., Blankenburgh, R., Bijlsma, R. M., Imholz, A. L.T., Stathonikos, N., Vreuls, W., Sanders, J., Rosenberg, E. H., Koop, E. A., Varga, Z., van Deurzen, C. H.M., Mooyaart, A. L., Córdoba, A., Groen, E., Bart, J., Willems, S. M., Zolota, V., Wesseling, J., Sapino, A., Chmielik, E., Ryska, A., Broeks, A., Voogd, A. C., van der Wall, E., Siesling, S., Salgado, R., Dackus, G. M.H.E., Hauptmann, M., Kok, M., and Linn, S. C.

Abstract

Background: In the absence of prognostic biomarkers, most patients with early-stage triple-negative breast cancer (eTNBC) are treated with combination chemotherapy. The identification of biomarkers to select patients for whom treatment de-escalation or escalation could be considered remains an unmet need. We evaluated the prognostic value of histopathologic traits in a unique cohort of young, (neo)adjuvant chemotherapy-naïve patients with early-stage (stage I or II), node-negative TNBC and long-term follow-up, in relation to stromal tumor-infiltrating lymphocytes (sTILs) for which the prognostic value was recently reported. Materials and methods: We studied all 485 patients with node-negative eTNBC from the population-based PARADIGM cohort which selected women aged <40 years diagnosed between 1989 and 2000. None of the patients had received (neo)adjuvant chemotherapy according to standard practice at the time. Associations between histopathologic traits and breast cancer-specific survival (BCSS) were analyzed with Cox proportional hazard models. Results: With a median follow-up of 20.0 years, an independent prognostic value for BCSS was observed for lymphovascular invasion (LVI) [adjusted (adj.) hazard ratio (HR) 2.35, 95% confidence interval (CI) 1.49-3.69], fibrotic focus (adj. HR 1.61, 95% CI 1.09-2.37) and sTILs (per 10% increment adj. HR 0.75, 95% CI 0.69-0.82). In the sTILs <30% subgroup, the presence of LVI resulted in a higher cumulative incidence of breast cancer death (at 20 years, 58%; 95% CI 41% to 72%) compared with when LVI was absent (at 20 years, 32%; 95% CI 26% to 39%). In the ≥75% sTILs subgroup, the presence of LVI might be associated with poor survival (HR 11.45, 95% CI 0.71-182.36, two deaths). We confirm the lack of prognostic value of androgen receptor expression and human epidermal growth factor receptor 2 -low status. Conclusions: sTILs, LVI and fibrotic focus provide independent prognostic information in young women with node-negat

Published
2024

17. Quality assurance of radiation therapy after breast-conserving surgery among patients in the BOOG 2013-08 trial

Author

Wintraecken, V.M., primary, Boersma, L.J., additional, van Roozendaal, L.M., additional, de Vries, J., additional, van Kuijk, S.M.J., additional, Vane, M.L.G., additional, van Dalen, T., additional, van der Hage, J.A., additional, Strobbe, L.J.A., additional, Linn, S.C., additional, Lobbes, M.B.I., additional, Poortmans, P.M.P, additional, Tjan-Heijnen, V.C.G., additional, van de Vijver, K.K.B.T., additional, Westenberg, A.H., additional, de Wilt, J.H.W., additional, Smidt, M.L., additional, and Simons, J.M., additional

Published
2023
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20. Extended adjuvant aromatase inhibition after sequential endocrine therapy (DATA): a randomised, phase 3 trial

Author

Kitzen, J.J.E.M., Strobbe, L.J.A., Kouwenhoven, E.A., van Dalen, T., van Overbeeke, A.J., Nuytinck, J.K.S., Arntz, I.E., Blaisse, R.J.B., Stockmann, H.B.A.C., Nijhuis, P.H.A., Veldhuis, G.J., Mastboom, W.J.B., van Riel, J.M.G.H., van Dam, J.H., den Boer, M.O., Agterof, M.J., de Roos, M.A.J., Roumen, R.M.H., van der Hoeven, J.J.M., Beeker, A., Koelemij, R., van Bochove, A., Madretsma, G.S., Siemerink, E.J.M., Guicherit, O.R., Vos, A.H., Nieuwenhuijzen, G.A.P., Kehrer, D.F.S., Valster, F.A.A., Tanis, B.C., van Voorthuizen, T., van der Velden, A.M.T., Hellingman, R.A., Vree, R., van Rossum-Schornagel, Q., Meerum Terwogt, J.M., van Leeuwen-Breuk, W.G., Haasjes, J.G., Davidis-van Schoonhoven, M.A., Vriens, E.J.C., Jagers, M., Muller, E.W., Schiphorst, P.P.J.B.M., van Groeningen, C.J., van Dijk, M.A., Janssens- van Vliet, E., Schepers, E.E.M., Merkus, J.W.S., van Diemen, N.G.J., van Doorn, R.C., Bosscha, K., den Toom, R., van der Velden, P.C., van Rossum, C.T.A.M., Oosterkamp, H.M., van Hillegersberg, R., Jas, B., Weernink, E.E.M., Ketel, J.M.A., Jansen, J.J., Maring, J.K., Govaert, M.J.P.M., Kamm, Y.J.L., Vleugel, M.M., Hovenga, S., de Boer, J., Potthoff, H., Sommeijer, D.W., van Dulken, E.J., Tjan-Heijnen, Vivianne C G, van Hellemond, Irene E G, Peer, Petronella G M, Swinkels, Astrid C P, Smorenburg, Carolien H, van der Sangen, Maurice J C, Kroep, Judith R, De Graaf, Hiltje, Honkoop, Aafke H, Erdkamp, Frans L G, van den Berkmortel, Franchette W P J, de Boer, Maaike, de Roos, Wilfred K, Linn, Sabine C, Imholz, Alexander L T, and Seynaeve, Caroline M

Published
2017
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25. OC-0765 Pre-operative single-dose partial breast irradiation: five-year results of the ABLATIVE trial

Author

Civil, Y., primary, Vasmel, J., additional, Charaghvandi, R., additional, Houweling, A., additional, Vreuls, C., additional, van Diest, P., additional, Witkamp, A., additional, Doeksen, A., additional, van Dalen, T., additional, Felderhof, J., additional, van Dam, I., additional, Slotman, B., additional, Kirby, A., additional, Verkooijen, H., additional, and van den Bongard, D., additional

Published
2023
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28. Surgical Oncologists and Nurses in Breast Cancer Care are Ready to Provide Pre-Test Genetic Counseling

Author

Cancer, Genetica Sectie Oncogenetica, Genetica Klinische Genetica, MS CGO, Genetica, Genetica Oper.Mang. Clinical Genetics, Staf strategisch beleid, Genetica Sectie Genoomdiagnostiek, Bokkers, K., Bleiker, E. M.A., Aalfs, C. M., van Dalen, T., Velthuizen, M. E., Duijveman, P., Sijmons, R. H., Koole, W., Schoenmaeckers, E. J.P., Ausems, M. G.E.M., Cancer, Genetica Sectie Oncogenetica, Genetica Klinische Genetica, MS CGO, Genetica, Genetica Oper.Mang. Clinical Genetics, Staf strategisch beleid, Genetica Sectie Genoomdiagnostiek, Bokkers, K., Bleiker, E. M.A., Aalfs, C. M., van Dalen, T., Velthuizen, M. E., Duijveman, P., Sijmons, R. H., Koole, W., Schoenmaeckers, E. J.P., and Ausems, M. G.E.M.

Published
2023

30. Patient-Reported Symptoms of Late Toxicity in Patients With Breast Cancer Treated With Hypofractionated Radiation Therapy and the Association With Quality of Life

Author

Batenburg, M.C.T., primary, Mink van der Molen, D.R., additional, van der Leij, F., additional, Doeksen, A., additional, van Dalen, T., additional, Schoenmaeckers, E.J.P., additional, Bijlsma, R.M., additional, Witkamp, A.J., additional, Ernst, M., additional, Sier, M.F., additional, Maarse, W., additional, van den Bongard, H.J.G.D., additional, and Verkooijen, H.M., additional

Published
2023
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32. The Utrecht cohort for Multiple BREast cancer intervention studies and Long-term evaLuAtion (UMBRELLA): objectives, design, and baseline results

Author

Young-Afat, D. A., van Gils, C. H., van den Bongard, H. J. G. D., Verkooijen, H. M., Gernaat, S. A., Gregorowitsch, M. L., May, A. M., Peeters, P. H., van der Pol, C. C., Witkamp, A. J., Pijnappel, R. M., Bijlsma, R. M., Maarse, W., Ausems, M. G., van Diest, P. J., van der Wall, E., van Dalen, T., Burgmans, I. P., de Roos, M. A., van Doorn, R. C., Baas, I. O., van Ooijen, B., Koelemij, R., and on behalf of the UMBRELLA Study Group

Published
2017
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34. Impact of lymphedema on health-related quality of life in early-stage breast cancer patients treated breast conserving therapy with or without sentinel lymph node biopsy: 2-year results from the randomized controlled trial BOOG2013–08

Author

Wintraecken, V., primary, Colier, E., additional, van Roozendaal, L.M., additional, Tjan-Heijnen, V.C.G., additional, Simons, J.M., additional, Strobbe, L.J.A., additional, van Maaren, M.C., additional, Boersma, L.J., additional, Lobbes, M.B.I., additional, van Dalen, T., additional, Linn, S.C., additional, Poortmans, P.M.P., additional, de Vries, J., additional, van Kuijk, S.M.J., additional, de Wilt, J., additional, and Smidt, M.L., additional

Published
2022
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35. Depression, loneliness and apathy in older breast cancer survivors: five-year follow-up from the Climb Every Mountain study

Author

Lemij, A., primary, De Glas, N.A., additional, van Dalen, T., additional, Guicherit, O.R., additional, Lans, T.E., additional, Linthorst-Niers, E.M.H., additional, Merkus, J.W.S., additional, van der Pol, C.C., additional, Vulink, A.J.E., additional, van Gerven, L., additional, Liefers, G.J., additional, and Portielje, J.E.A., additional

Published
2022
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40. Physical function in older patients with breast cancer: five-year follow-up from the CLIMB study

Author

Lemij, A., primary, de Glas, N., additional, Derks, M., additional, Bastiaannet, E., additional, Merkus, J., additional, Lans, T., additional, van der Pol, C., additional, van Dalen, T., additional, Vulink, A., additional, van Gerven, L., additional, Guicherit, O., additional, Linthorst-Niers, E., additional, Liefers, G.J., additional, and Portielje, J., additional

Published
2022
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41. 171P Association of breast cancer therapy with cognitive decline in older women with early breast cancer: Findings from the CLIMB study

Author

Baltussen, J., primary, Derks, M.G.M., additional, Lemij, A.A., additional, de Glas, N.A., additional, Fiocco, M., additional, Linthorst-Niers, E., additional, Vulink, A., additional, Van Gerven, L., additional, Guicherit, O.R., additional, Van Dalen, T., additional, Merkus, J.W.S., additional, Lans, T., additional, Van der Pol, C.C., additional, Mooijaart, S.P., additional, Portielje, J.E.A., additional, and Liefers, G.J., additional

Published
2022
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48. Limiting systemic endocrine overtreatment in postmenopausal breast cancer patients with an ultralow classification of the 70-gene signature

Author

MS CGO, MS Medische Oncologie, Cancer, Pathologie, Opdam, M, van der Noort, V, Kleijn, M, Glas, A, Mandjes, I, Kleiterp, S, Hilbers, F S, Kruger, D T, Bins, A D, de Jong, P C, Schiphorst, P P J B M, van Dalen, T, Flameling, B, Rietbroek, R C, Beeker, A, van den Heiligenberg, S M, Bakker, S D, Wymenga, A N M, Oving, I M, Bijlsma, R M, van Diest, P J, Vermorken, J B, van Tinteren, H, Linn, S C, MS CGO, MS Medische Oncologie, Cancer, Pathologie, Opdam, M, van der Noort, V, Kleijn, M, Glas, A, Mandjes, I, Kleiterp, S, Hilbers, F S, Kruger, D T, Bins, A D, de Jong, P C, Schiphorst, P P J B M, van Dalen, T, Flameling, B, Rietbroek, R C, Beeker, A, van den Heiligenberg, S M, Bakker, S D, Wymenga, A N M, Oving, I M, Bijlsma, R M, van Diest, P J, Vermorken, J B, van Tinteren, H, and Linn, S C

Published
2022

49. Effects of structured involvement of the primary care team versus standard care after a cancer diagnosis on patient satisfaction and healthcare use: the GRIP randomised controlled trial

Author

Cancer, Infection & Immunity, JC onderzoeksprogramma Cancer, HAG Oncologie, MS Gynaecologische Oncologie, MS CGO, MS MDL 1, Speerpunt Cancer, Julius Centrum, Child Health, Circulatory Health, JC Overig onderzoek, Epi Kanker, Perfors, I. A.A., Helsper, C. W., Noteboom, E. A., Visserman, E. A., van Dorst, E. B.L., van Dalen, T., Verhagen, M. A.M.T., Witkamp, A. J., Koelemij, R., Flinterman, A. E., Pruissen-Peeters, K. A.B.M., Schramel, F. M.N.H., van Rens, M. T.M., Ernst, M. F., Moons, L. M.G., van der Wall, E., de Wit, N. J., May, A. M., Cancer, Infection & Immunity, JC onderzoeksprogramma Cancer, HAG Oncologie, MS Gynaecologische Oncologie, MS CGO, MS MDL 1, Speerpunt Cancer, Julius Centrum, Child Health, Circulatory Health, JC Overig onderzoek, Epi Kanker, Perfors, I. A.A., Helsper, C. W., Noteboom, E. A., Visserman, E. A., van Dorst, E. B.L., van Dalen, T., Verhagen, M. A.M.T., Witkamp, A. J., Koelemij, R., Flinterman, A. E., Pruissen-Peeters, K. A.B.M., Schramel, F. M.N.H., van Rens, M. T.M., Ernst, M. F., Moons, L. M.G., van der Wall, E., de Wit, N. J., and May, A. M.

Published
2022

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