1. Brain Damage and Visuospatial Impairments: Exploring Early Structure-Function Associations in Children Born Very Preterm
- Author
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van Gils, M.M. (Maud M.), Dudink, J. (Jeroen), Reiss, I.K.M. (Irwin), Swarte, R.M.C. (Renate), Steen, J. (Hans) van der, Pel, J.J.M. (Johan), Kooiker, M.J.G. (Marlou), van Gils, M.M. (Maud M.), Dudink, J. (Jeroen), Reiss, I.K.M. (Irwin), Swarte, R.M.C. (Renate), Steen, J. (Hans) van der, Pel, J.J.M. (Johan), and Kooiker, M.J.G. (Marlou)
- Abstract
Background: To provide insight into early neurosensory development in children born very preterm, we assessed the association between early structural brain damage and functional visuospatial attention and motion processing from one to two years corrected age. Methods: In 112 children born at <32 weeks gestational age, we assessed brain damage and growth with a standardized scoring system on magnetic resonance imaging (MRI; 1.5 Tesla) scans performed at 29 to 35 weeks gestational age. Of the children with an MRI scan, 82 participated in an eye tracking-based assessment of visuospatial attention and motion processing (Tobii T60XL) at one year corrected age and 59 at two years corrected age. Results: MRI scoring showed good intra- and inter-rater reproducibility. At one year, 10% children had delayed attentional reaction times and 23% had delayed motion reaction times. Moderate to severe brain damage significantly correlated with sl
- Published
- 2020
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