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223 results on '"van Hagen, Johanna M."'

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1. The detection of a strong episignature for Chung–Jansen syndrome, partially overlapping with Börjeson–Forssman–Lehmann and White–Kernohan syndromes

2. Clinical and functional heterogeneity associated with the disruption of retinoic acid receptor beta

4. Comprehensive EHMT1 variants analysis broadens genotype-phenotype associations and molecular mechanisms in Kleefstra syndrome

5. DISP1 deficiency: Monoallelic and biallelic variants cause a spectrum of midline craniofacial malformations

7. Biallelic Mutations in ADPRHL2, Encoding ADP-Ribosylhydrolase 3, Lead to a Degenerative Pediatric Stress-Induced Epileptic Ataxia Syndrome

8. The phenotypic spectrum and genotype-phenotype correlations in 106 patients with variants in major autism gene CHD8

9. Generation of induced pluripotent stem cell lines from two unrelated patients affected by intellectual disability carrying homozygous variants in SGIP1

11. DNA methylation episignature and comparative epigenomic profiling for Pitt-Hopkins syndrome caused by TCF4 variants

12. Lysine acetyltransferase 8 is involved in cerebral development and syndromic intellectual disability

13. The detection of a strong episignature for Chung-Jansen syndrome, partially overlapping with Börjeson-Forssman-Lehmann and White-Kernohan syndromes

14. Comprehensive EHMT1 variants analysis broadens genotype-phenotype associations and molecular mechanisms in Kleefstra syndrome

15. Refining the 9q34.3 microduplication syndrome reveals mild neurodevelopmental features associated with a distinct global DNA methylation profile

16. SYNGAP1 encephalopathy: A distinctive generalized developmental and epileptic encephalopathy

18. Phenotype and genotype in 103 patients with tricho-rhino-phalangeal syndrome

19. A clustering of heterozygous missense variants in the crucial chromatin modifier WDR5 defines a new neurodevelopmental disorder

20. SYNGAP1 encephalopathy: A distinctive generalized developmental and epileptic encephalopathy

21. MissenseMED12variants in 22 males with intellectual disability: From nonspecific symptoms to complete syndromes

22. The phenotypic spectrum and genotype-phenotype correlations in 106 patients with variants in major autism gene CHD8

23. Erratum:Biallelic Mutations in ADPRHL2, Encoding ADP-Ribosylhydrolase 3, Lead to a Degenerative Pediatric Stress-Induced Epileptic Ataxia Syndrome (The American Journal of Human Genetics (2018) 103(3) (431–439), (S0002929718302374), (10.1016/j.ajhg.2018.07.010))

24. Biallelic BUB1 mutations cause microcephaly, developmental delay, and variable effects on cohesion and chromosome segregation

25. Biallelic Mutations in ADPRHL2, Encoding ADP-Ribosylhydrolase 3, Lead to a Degenerative Pediatric Stress-Induced Epileptic Ataxia Syndrome

26. A clustering of missense variants in the crucial chromatin modifier WDR5 defines a new neurodevelopmental disorder

27. High-sensitivity sequencing reveals multi-organ somatic mosaicism causing DICER1 syndrome

29. Etiology and pathogenesis of robin sequence in a large Dutch cohort

30. A Study of the Clinical and Radiological Features in a Cohort of 93 Patients with a COL2A1 Mutation Causing Spondyloepiphyseal Dysplasia Congenita or a Related Phenotype

31. Heterozygous germline mutations in the CBL tumor-suppressor gene cause a Noonan syndrome-like phenotype

33. SYNGAP1 encephalopathy

34. Biallelic Mutations in ADPRHL2, Encoding ADP-Ribosylhydrolase 3, Lead to a Degenerative Pediatric Stress-Induced Epileptic Ataxia Syndrome (vol 103, pg 431, 2018)

35. Cellular and clinical impact of haploinsufficiency for genes involved in ATR signaling

38. CACNA1I gain-of-function mutations differentially affect channel gating and cause neurodevelopmental disorders

40. Meier–Gorlin Syndrome: Growth and Secondary Sexual Development of a Microcephalic Primordial Dwarfism Disorder

41. Two CaV3.3 (CACNA1I) Gain-of-Function Mutations Linked to Epilepsy and Intellectual Disability Affect Gating Properties and the Window Current

45. upd(20)mat is a rare cause of the Silver-Russell-syndrome-like phenotype:Two unrelated cases and screening of large cohorts

46. Lysine acetyltransferase 8 is involved in cerebral development and syndromic intellectual disability

47. Lack of genotype-phenotype correlation in basal cell nevus syndrome: A Dutch multicenter retrospective cohort study

48. Erratum: Biallelic Mutations in ADPRHL2, Encoding ADP-Ribosylhydrolase 3, Lead to a Degenerative Pediatric Stress-Induced Epileptic Ataxia Syndrome (The American Journal of Human Genetics (2018) 103(3) (431–439)(S0002929718302374)(10.1016/j.ajhg.2018.07.010))

49. De novo mutations in the SET nuclear proto-oncogene, encoding a component of the inhibitor of histone acetyltransferases (INHAT) complex in patients with nonsyndromic intellectual disability

50. CACNA1I gain-of-function mutations differentially affect channel gating and cause neurodevelopmental disorders.

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