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2. Attributable mortality of candidemia – Results from the ECMM Candida III multinational European Observational Cohort Study

Author

Salmanton-García, Jon, Cornely, Oliver A., Stemler, Jannik, Barać, Aleksandra, Steinmann, Jörg, Siváková, Alena, Akalin, Emin Halis, Arikan-Akdagli, Sevtap, Loughlin, Laura, Toscano, Cristina, Narayanan, Manjusha, Rogers, Benedict, Willinger, Birgit, Akyol, Deniz, Roilides, Emmanuel, Lagrou, Katrien, Mikulska, Malgorzata, Denis, Blandine, Ponscarme, Diane, Scharmann, Urlike, Azap, Alpay, Lockhart, Deborah, Bicanic, Tihana, Kron, Florian, Erben, Nurettin, Rautemaa-Richardson, Riina, Goodman, Anna L., Garcia-Vidal, Carolina, Lass-Flörl, Cornelia, Gangneux, Jean-Pierre, Taramasso, Lucia, Ruiz, Maite, Schick, Yael, Van Wijngaerden, Eric, Milacek, Christopher, Giacobbe, Daniele Roberto, Logan, Clare, Rooney, Emily, Gori, Andrea, Akova, Murat, Bassetti, Matteo, Hoenigl, Martin, and Koehler, Philipp

Published
2024
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3. Guideline adherence and survival of patients with candidaemia in Europe: results from the ECMM Candida III multinational European observational cohort study

Author

Tumbarello, Mario, Talento, Alida Fe, Ruiz, Alba C, Racil, Zdenek, Stoma, Igor, Calbacho, Maria, Van Wijngaerden, Eric, Henriques, Júlia, Jordan, Harriett, Ferroni, Valentina, Ozyurt, Ozlem Koyuncu, Milacek, Christopher, Krause, Robert, Zurl, Christoph, Backx, Matthijs, Li, Ang, Seufert, Raphael, Tomazin, Rok, Blankenheim, Yael, Dávila-Valls, Julio, García-Clemente, Paloma, Freiberger, Tomas, Buil, Jochem, Meis, Jacques F, Akyol, Deniz, Guegan, Hélène, Logan, Clare, Hoenigl, Martin, Salmanton-García, Jon, Egger, Matthias, Gangneux, Jean-Pierre, Bicanic, Tihana, Arikan-Akdagli, Sevtap, Alastruey-Izquierdo, Ana, Klimko, Nikolai, Barac, Aleksandra, Özenci, Volkan, Meijer, Eelco F J, Khanna, Nina, Bassetti, Matteo, Rautemaa-Richardson, Riina, Lagrou, Katrien, Adam, Kai-Manuel, Akalin, Emin Halis, Akova, Murat, Arsic Arsenijevic, Valentina, Aujayeb, Avinash, Blennow, Ola, Bretagne, Stéphane, Danion, François, Denis, Blandine, de Jonge, Nick Alexander, Desoubeaux, Guillaume, Drgona, Lubos, Erben, Nurettin, Gori, Andrea, García Rodríguez, Julio, Garcia-Vidal, Carolina, Giacobbe, Daniele Roberto, Goodman, Anna L, Hamal, Petr, Hammarström, Helena, Toscano, Cristina, Lanternier, Fanny, Lass-Flörl, Cornelia, Lockhart, Deborah E A, Longval, Thomas, Loughlin, Laura, Matos, Tadeja, Mikulska, Malgorzata, Narayanan, Manjusha, Martín-Pérez, Sonia, Prattes, Juergen, Rogers, Benedict, Rahimli, Laman, Ruiz, Maite, Roilides, Emmanuel, Samarkos, Michael, Scharmann, Ulrike, Sili, Uluhan, Sipahi, Oguz Resat, Sivakova, Alena, Steinmann, Joerg, Trauth, Janina, Turhan, Ozge, Van Praet, Jens, Vena, Antonio, White, P Lewis, Willinger, Birgit, Tortorano, Anna Maria, Arendrup, Maiken C, Koehler, Philipp, and Cornely, Oliver A

Published
2023
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4. Rezafungin versus caspofungin for treatment of candidaemia and invasive candidiasis (ReSTORE): a multicentre, double-blind, double-dummy, randomised phase 3 trial

Author

Akova, Murat, AlAgha, Rawan, Alangaden, George, Albrecht, Svenja J, Alexander, Barbara, Al-Obaidi, Mohanad, Ambasch, German, Armestar Rodriguez, Fernando, Azap, Alpay, Baffoe-Bonnie, Anthony, Belkhir, Leila, Ben-Ami, Ronen, Boutoille, David, Cascio, Antonio, Chai, Louis YA, Chaiwarith, Romanee, Chayakulkeeree, Methee, Chen, Sharon, Chen, Yee-Chun, Chen, Yen-Hsu, Choi, Jun Yong, Choi, Young Hwa, Chotiprasitsakul, Darunee, Chung, Jin Won, Danion, François, Denis, Blandine, Diaz Santos, Emilio, Dictar, Miguel O, Diltoer, Marc, Dupont, Herve, Feng, Sizhou, Ferre Colomer, Maria Angeles, Ferrer, Ricard, Forel, Jean-Marie Fernand Roger, Fortún-Abete, Jesús, Garcia-Diaz, Julia, Girardis, Massimo, He, Fang, Hites, Maya, Ho, Mao-Wang, Honore, Patrick, Horcajada Gallego, Juan Pablo, Huang, Haihui, Huang, Po-Yen, Huang, Yong, Hussein, Osamah, Intalapaporn, Poj, Jaruratanasirikul, Sutep, Jauregui-Peredo, Luis, Johnson, Misty, Jung, Dong Sik, Jutivorakool, Kamonwan, Kern, Winfried V, Kett, Daniel H, Khawcharoenporn, Thana, Kim, Young Keun, Koehler, Philipp, Kotanidou, Anastasia, Lachiewicz, Anne, Lin, Qinhan, Lopez Cortes, Luis Eduardo, Luo, Hong, Luzzati, Roberto, Maor, Yasmin, McCarty, Todd, Merelli, Maria, Merino Amador, Paloma, Midturi, John, Migliorino, Guglielmo Marco, Mira, Jean-Paul, Mootsikapun, Piroon, Morrissey, Orla, Munoz Garcia de Paredes, Patricia, Mussini, Cristina, Mylonakis, Eleftherios, Nseir, Saadalla, Nseir, William, Odabasi, Zekaver, Papastamopoulos, Vasileios, Paterson, David, Patterson, Thomas F, Peck, Kyong Ran, Peng, Zhiyong, Permpalung, Nitipong, Plantefeve, Gaetan J, Poromanski, Ivan G, Powell, Debra, Psichogiou, Mina, Puah, Ser Hon, Pullman, John, Rahav, Galia, Martinez, Antonio Ramos, Ramos Ramos, Juan Carlos, Raz-Pasteur, Ayelet, Restrepo Castro, Carlos A, Riera, Fernando, Roblot, France, Rodriguez Alvarez, Regino Jose, Rogers, Benjamin, Roilides, Emmanuel, Sanchez Vallejo, Gregorio, Sganga, Gabriele, Sipsas, Nikolaos, Slavin, Monica, Soriano, Alex, Spec, Andrej, Strahilevitz, Jacob, Tancheva, Dora M, Tao, Zhen, Teschner, Daniel, Thompson, George R, Van Wijngaerden, Eric, Vazquez, Jose, Vergidis, Paschalis, Viale, Pierluigi, Wang, Fu-Der, Wang, Shifu, Weber, Gabriel, Weng, Jianyu, Xu, Jinfu, Yao, Li, Yavuz, Serap, Yilmaz, Mesut, Young, Jo-Anne, Zarate, Abel H, Zeng, Jun, Zhang, Yong, Thompson, George R, III, Cornely, Oliver A, Kullberg, Bart Jan, Kollef, Marin, Honore, Patrick M, Bassetti, Matteo, Poromanski, Ivan, Dignani, Cecilia, Das, Anita F, Sandison, Taylor, and Pappas, Peter G

Published
2023
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5. Full-genome next-generation sequencing of hepatitis C virus to assess the accuracy of genotyping by the commercial assay LiPA and the prevalence of resistance-associated substitutions in a Belgian cohort

Author

Christensen, Kasper T., Pierard, Florian, Beuselinck, Kurt, Bonsall, David, Bowden, Rory, Lagrou, Katrien, Nevens, Frederik, Schrooten, Yoeri, Simmonds, Peter, Vandamme, Anne-Mieke, Van Wijngaerden, Eric, Dierckx, Tim, Cuypers, Lize, and Van Laethem, Kristel

Published
2022
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7. A public health value-based healthcare paradigm for HIV

Author

Vermeersch, Sebastian, Demeester, Rémy P., Ausselet, Nathalie, Callens, Steven, De Munter, Paul, Florence, Eric, Goffard, Jean-Christophe, Henrard, Sophie, Lacor, Patrick, Messiaen, Peter, Libois, Agnès, Seyler, Lucie, Uurlings, Françoise, Vandecasteele, Stefaan J., Van Wijngaerden, Eric, Yombi, Jean-Cyr, Annemans, Lieven, and De Wit, Stéphane

Published
2022
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9. Itraconazole for COVID-19: preclinical studies and a proof-of-concept randomized clinical trial

Author

Liesenborghs, Laurens, Spriet, Isabel, Jochmans, Dirk, Belmans, Ann, Gyselinck, Iwein, Teuwen, Laure-Anne, ter Horst, Sebastiaan, Dreesen, Erwin, Geukens, Tatjana, Engelen, Matthias M., Landeloos, Ewout, Geldhof, Vincent, Ceunen, Helga, Debaveye, Barbara, Vandenberk, Bert, Van der Linden, Lorenz, Jacobs, Sofie, Langendries, Lana, Boudewijns, Robbert, Do, Thuc Nguyen Dan, Chiu, Winston, Wang, Xinyu, Zhang, Xin, Weynand, Birgit, Vanassche, Thomas, Devos, Timothy, Meyfroidt, Geert, Janssens, Wim, Vos, Robin, Vermeersch, Pieter, Wauters, Joost, Verbeke, Geert, De Munter, Paul, Kaptein, Suzanne J.F., Rocha-Pereira, Joana, Delang, Leen, Van Wijngaerden, Eric, Neyts, Johan, and Verhamme, Peter

Published
2021
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11. Global and regional epidemiology of HIV-1 recombinants in 1990–2015: a systematic review and global survey

Author

Abimiku, Alash'le G, Agwale, Simon, Archibald, Chris, Avidor, Boaz, Barbás, María Gabriela, Barre-Sinoussi, Francoise, Barugahare, Banson, Belabbes, El Hadj, Bertagnolio, Silvia, Birx, Deborah, Bobkov, Aleksei F, Brandful, James, Bredell, Helba, Brennan, Catherine A, Brooks, James, Bruckova, Marie, Buonaguro, Luigi, Buonaguro, Franco, Buttò, Stefano, Buvé, Anne, Campbell, Mary, Carr, Jean, Carrera, Alex, Carrillo, Manuel Gómez, Celum, Connie, Chaplin, Beth, Charles, Macarthur, Chatzidimitriou, Dimitrios, Chen, Zhiwei, Chijiwa, Katsumi, Cooper, David, Cunningham, Philip, Dagnra, Anoumou, de Gascun, Cillian F, Del Amo, Julia, Delgado, Elena, Dietrich, Ursula, Dwyer, Dominic, Ellenberger, Dennis, Ensoli, Barbara, Essex, Max, Gao, Feng, Fleury, Hervé, Fonjungo, Peter N, Foulongne, Vincent, Gadkari, Deepak A, García, Federico, Garsia, Roger, Gershy-Damet, Guy Michel, Glynn, Judith R, Goodall, Ruth, Grossman, Zehava, Lindenmeyer-Guimarães, Monick, Hahn, Beatrice, Hamers, Raph L, Hamouda, Osamah, Handema, Ray, He, Xiang, Herbeck, Joshua, Ho, David D, Holguin, Africa, Hosseinipour, Mina, Hunt, Gillian, Ito, Masahiko, Bel Hadj Kacem, Mohamed Ali, Kahle, Erin, Kaleebu, Pontiano, Kalish, Marcia, Kamarulzaman, Adeeba, Kang, Chun, Kanki, Phyllis, Karamov, Edward, Karasi, Jean-Claude, Kayitenkore, Kayitesi, Kelleher, Tony, Kitayaporn, Dwip, Kostrikis, Leondios G, Kucherer, Claudia, Lara, Claudia, Leitner, Thomas, Liitsola, Kirsi, Lingappa, Jai, Linka, Marek, Lorenzana de Rivera, Ivette, Lukashov, Vladimir, Maayan, Shlomo, Mayr, Luzia, McCutchan, Francine, Meda, Nicolas, Menu, Elisabeth, Mhalu, Fred, Mloka, Doreen, Mokili, John L, Montes, Brigitte, Mor, Orna, Morgado, Mariza, Mosha, Fausta, Moussi, Awatef, Mullins, James, Najera, Rafael, Nasr, Mejda, Ndembi, Nicaise, Neilson, Joel R, Nerurkar, Vivek R, Neuhann, Florian, Nolte, Claudine, Novitsky, Vlad, Nyambi, Philippe, Ofner, Marianna, Paladin, Fem J, Papa, Anna, Pape, Jean, Parkin, Neil, Parry, Chris, Peeters, Martine, Pelletier, Alexandra, Pérez-Álvarez, Lucía, Pillay, Deenan, Pinto, Angie, Quang, Trinh Duy, Rademeyer, Cecilia, Raikanikoda, Filimone, Rayfield, Mark A, Reynes, Jean-Marc, Rinke de Wit, Tobias, Robbins, Kenneth E, Rolland, Morgane, Rousseau, Christine, Salazar-Gonzales, Jesus, Salem, Hanan, Salminen, Mika, Salomon, Horacio, Sandstrom, Paul, Santiago, Mario L, Sarr, Abdoulaye D, Schroeder, Bryan, Segondy, Michel, Selhorst, Philippe, Sempala, Sylvester, Servais, Jean, Shaik, Ansari, Shao, Yiming, Slim, Amine, Soares, Marcelo A, Songok, Elijah, Stewart, Debbie, Stokes, Julie, Subbarao, Shambavi, Sutthent, Ruengpung, Takehisa, Jun, Tanuri, Amilcar, Tee, Kok Keng, Thapa, Kiran, Thomson, Michael, Tran, Tyna, Urassa, Willy, Ushijima, Hiroshi, van de Perre, Philippe, van der Groen, Guido, van Laethem, Kristel, van Oosterhout, Joep, van Sighem, Ard, van Wijngaerden, Eric, Vandamme, Anne-Mieke, Vercauteren, Jurgen, Vidal, Nicole, Wallace, Lesley, Williamson, Carolyn, Wolday, Dawit, Xu, Jianqing, Yang, Chunfu, Zhang, Linqi, Zhang, Rong, Hemelaar, Joris, Elangovan, Ramyiadarsini, Yun, Jason, Dickson-Tetteh, Leslie, Kirtley, Shona, Gouws-Williams, Eleanor, and Ghys, Peter D

Published
2020
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12. Phylogenetic Analysis of Hepatitis C Virus Infections in a Large Belgian Cohort Using Next-Generation Sequencing of Full-Length Genomes

Author

Christensen, Kasper T., primary, Pierard, Florian, additional, Bonsall, David, additional, Bowden, Rory, additional, Barnes, Eleanor, additional, Florence, Eric, additional, Ansari, M. Azim, additional, Nguyen, Dung, additional, de Cesare, Mariateresa, additional, Nevens, Frederik, additional, Robaeys, Geert, additional, Schrooten, Yoeri, additional, Busschots, Dana, additional, Simmonds, Peter, additional, Vandamme, Anne-Mieke, additional, Van Wijngaerden, Eric, additional, Dierckx, Tim, additional, Cuypers, Lize, additional, and Van Laethem, Kristel, additional

Published
2023
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14. Global and regional molecular epidemiology of HIV-1, 1990–2015: a systematic review, global survey, and trend analysis

Author

Abimiku, Alash'le G, Agwale, Simon, Archibald, Chris, Avidor, Boaz, Barbás, María Gabriela, Barre-Sinoussi, Francoise, Barugahare, Banson, Belabbes, El Hadj, Bertagnolio, Silvia, Birx, Deborah, Bobkov, Aleksei F, Brandful, James, Bredell, Helba, Brennan, Catherine A, Brooks, James, Bruckova, Marie, Buonaguro, Luigi, Buonaguro, Franco, Buttò, Stefano, Buve, Anne, Campbell, Mary, Carr, Jean, Carrera, Alex, Carrillo, Manuel Gómez, Celum, Connie, Chaplin, Beth, Charles, Macarthur, Chatzidimitriou, Dimitrios, Chen, Zhiwei, Chijiwa, Katsumi, Cooper, David, Cunningham, Philip, Dagnra, Anoumou, de Gascun, Cillian F, Del Amo, Julia, Delgado, Elena, Dietrich, Ursula, Dwyer, Dominic, Ellenberger, Dennis, Ensoli, Barbara, Essex, Max, Gao, Feng, Fleury, Herve, Fonjungo, Peter N, Foulongne, Vincent, Gadkari, Deepak A, García, Federico, Garsia, Roger, Gershy-Damet, Guy Michel, Glynn, Judith R, Goodall, Ruth, Grossman, Zehava, Lindenmeyer-Guimarães, Monick, Hahn, Beatrice, Hamers, Raph L, Hamouda, Osamah, Handema, Ray, He, Xiang, Herbeck, Joshua, Ho, David D, Holguin, Africa, Hosseinipour, Mina, Hunt, Gillian, Ito, Masahiko, Bel Hadj Kacem, Mohamed Ali, Kahle, Erin, Kaleebu, Pontiano Kaleebu, Kalish, Marcia, Kamarulzaman, Adeeba, Kang, Chun, Kanki, Phyllis, Karamov, Edward, Karasi, Jean-Claude, Kayitenkore, Kayitesi, Kelleher, Tony, Kitayaporn, Dwip, Kostrikis, Leondios G, Kucherer, Claudia, Lara, Claudia, Leitner, Thomas, Liitsola, Kirsi, Lingappa, Jai, Linka, Marek, Lorenzana de Rivera, Ivette, Lukashov, Vladimir, Maayan, Shlomo, Mayr, Luzia, McCutchan, Francine, Meda, Nicolas, Menu, Elisabeth, Mhalu, Fred, Mloka, Doreen, Mokili, John L, Montes, Brigitte, Mor, Orna, Morgado, Mariza, Mosha, Fausta, Moussi, Awatef, Mullins, James, Najera, Rafael, Nasr, Mejda, Ndembi, Nicaise, Neilson, Joel R, Nerurkar, Vivek R, Neuhann, Florian, Nolte, Claudine, Novitsky, Vlad, Nyambi, Philippe, Ofner, Marianna, Paladin, Fem J, Papa, Anna, Pape, Jean, Parkin, Neil, Parry, Chris, Peeters, Martine, Pelletier, Alexandra, Pérez-Álvarez, Lucía, Pillay, Deenan, Pinto, Angie, Quang, Trinh Duy, Rademeyer, Cecilia, Raikanikoda, Filimone, Rayfield, Mark A, Reynes, Jean-Marc, Rinke de Wit, Tobias, Robbins, Kenneth E, Rolland, Morgane, Rousseau, Christine, Salazar-Gonzales, Jesus, Salem, Hanan, Salminen, Mika, Salomon, Horacio, Sandstrom, Paul, Santiago, Mario L, Sarr, Abdoulaye D, Schroeder, Bryan, Segondy, Michel, Selhorst, Philippe, Sempala, Sylvester, Servais, Jean, Shaik, Ansari, Shao, Yiming, Slim, Amine, Soares, Marcelo A, Songok, Elijah, Stewart, Debbie, Stokes, Julie, Subbarao, Shambavi, Sutthent, Ruengpung, Takehisa, Jun, Tanuri, Amilcar, Tee, Kok Keng, Thapa, Kiran, Thomson, Michael, Tran, Tyna, Urassa, Willy, Ushijima, Hiroshi, van de Perre, Philippe, van der Groen, Guido, van Laethem, Kristel, van Oosterhout, Joep, van Sighem, Ard, van Wijngaerden, Eric, Vandamme, Anne-Mieke, Vercauteren, Jurgen, Vidal, Nicole, Wallace, Lesley, Williamson, Carolyn, Wolday, Dawit, Xu, Jianqing, Yang, Chunfu, Zhang, Linqi, Zhang, Rong, Hemelaar, Joris, Elangovan, Ramyiadarsini, Yun, Jason, Dickson-Tetteh, Leslie, Fleminger, Isabella, Kirtley, Shona, Williams, Brian, Gouws-Williams, Eleanor, and Ghys, Peter D

Published
2019
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15. The genealogical population dynamics of HIV-1 in a large transmission chain: bridging within and among host evolutionary rates.

Author

Vrancken, Bram, Rambaut, Andrew, Suchard, Marc A, Drummond, Alexei, Baele, Guy, Derdelinckx, Inge, Van Wijngaerden, Eric, Vandamme, Anne-Mieke, Van Laethem, Kristel, and Lemey, Philippe

Subjects
Humans, HIV-1, HIV Infections, Evolution, Molecular, Host-Pathogen Interactions, Evolution, Molecular, Mathematical Sciences, Biological Sciences, Information and Computing Sciences, Bioinformatics
Abstract

Transmission lies at the interface of human immunodeficiency virus type 1 (HIV-1) evolution within and among hosts and separates distinct selective pressures that impose differences in both the mode of diversification and the tempo of evolution. In the absence of comprehensive direct comparative analyses of the evolutionary processes at different biological scales, our understanding of how fast within-host HIV-1 evolutionary rates translate to lower rates at the between host level remains incomplete. Here, we address this by analyzing pol and env data from a large HIV-1 subtype C transmission chain for which both the timing and the direction is known for most transmission events. To this purpose, we develop a new transmission model in a Bayesian genealogical inference framework and demonstrate how to constrain the viral evolutionary history to be compatible with the transmission history while simultaneously inferring the within-host evolutionary and population dynamics. We show that accommodating a transmission bottleneck affords the best fit our data, but the sparse within-host HIV-1 sampling prevents accurate quantification of the concomitant loss in genetic diversity. We draw inference under the transmission model to estimate HIV-1 evolutionary rates among epidemiologically-related patients and demonstrate that they lie in between fast intra-host rates and lower rates among epidemiologically unrelated individuals infected with HIV subtype C. Using a new molecular clock approach, we quantify and find support for a lower evolutionary rate along branches that accommodate a transmission event or branches that represent the entire backbone of transmitted lineages in our transmission history. Finally, we recover the rate differences at the different biological scales for both synonymous and non-synonymous substitution rates, which is only compatible with the 'store and retrieve' hypothesis positing that viruses stored early in latently infected cells preferentially transmit or establish new infections upon reactivation.

Published
2014

16. High Burden of COVID-19-Associated Pulmonary Aspergillosis in Severely Immunocompromised Patients Requiring Mechanical Ventilation

Author

Feys, Simon, primary, Lagrou, Katrien, additional, Lauwers, Hanne Moon, additional, Haenen, Koen, additional, Jacobs, Cato, additional, Brusselmans, Marius, additional, Debaveye, Yves, additional, Hermans, Greet, additional, Hoenigl, Martin, additional, Maertens, Johan, additional, Meersseman, Philippe, additional, Peetermans, Marijke, additional, Spriet, Isabel, additional, Vandenbriele, Christophe, additional, Vanderbeke, Lore, additional, Vos, Robin, additional, Van Wijngaerden, Eric, additional, Wilmer, Alexander, additional, and Wauters, Joost, additional

Published
2023
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17. A Pathology-based Case Series of Influenza- and COVID-19–associated Pulmonary Aspergillosis: The Proof Is in the Tissue

Author

Vanderbeke, Lore, primary, Jacobs, Cato, additional, Feys, Simon, additional, Reséndiz-Sharpe, Agustin, additional, Debaveye, Yves, additional, Hermans, Greet, additional, Humblet-Baron, Stephanie, additional, Lagrou, Katrien, additional, Meersseman, Philippe, additional, Peetermans, Marijke, additional, Seldeslachts, Laura, additional, Vanstapel, Arno, additional, Vande Velde, Greetje, additional, Van Wijngaerden, Eric, additional, Wilmer, Alexander, additional, Verbeken, Erik, additional, De Hertogh, Gert, additional, and Wauters, Joost, additional

Published
2023
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19. Outcome and Treatment of Nocardiosis After Solid Organ Transplantation: New Insights From a European Study

Author

European Study Group for Nocardia in Solid Organ Transplantation, Lebeaux, David, Freund, Romain, van Delden, Christian, Guillot, Hélène, Marbus, Sierk D., Matignon, Marie, Van Wijngaerden, Eric, Douvry, Benoit, De Greef, Julien, Vuotto, Fanny, Tricot, Leïla, Fernández-Ruiz, Mario, Dantal, Jacques, Hirzel, Cédric, Jais, Jean-Philippe, Rodriguez-Nava, Veronica, Jacobs, Frédérique, Lortholary, Olivier, and Coussement, Julien

Published
2017

20. Guideline adherence and survival of patients with candidaemia in Europe: results from the ECMM Candida III multinational European observational cohort study

Author

Hoenigl, Martin, primary, Salmanton-García, Jon, additional, Egger, Matthias, additional, Gangneux, Jean-Pierre, additional, Bicanic, Tihana, additional, Arikan-Akdagli, Sevtap, additional, Alastruey-Izquierdo, Ana, additional, Klimko, Nikolai, additional, Barac, Aleksandra, additional, Özenci, Volkan, additional, Meijer, Eelco F J, additional, Khanna, Nina, additional, Bassetti, Matteo, additional, Rautemaa-Richardson, Riina, additional, Lagrou, Katrien, additional, Adam, Kai-Manuel, additional, Akalin, Emin Halis, additional, Akova, Murat, additional, Arsic Arsenijevic, Valentina, additional, Aujayeb, Avinash, additional, Blennow, Ola, additional, Bretagne, Stéphane, additional, Danion, François, additional, Denis, Blandine, additional, de Jonge, Nick Alexander, additional, Desoubeaux, Guillaume, additional, Drgona, Lubos, additional, Erben, Nurettin, additional, Gori, Andrea, additional, García Rodríguez, Julio, additional, Garcia-Vidal, Carolina, additional, Giacobbe, Daniele Roberto, additional, Goodman, Anna L, additional, Hamal, Petr, additional, Hammarström, Helena, additional, Toscano, Cristina, additional, Lanternier, Fanny, additional, Lass-Flörl, Cornelia, additional, Lockhart, Deborah E A, additional, Longval, Thomas, additional, Loughlin, Laura, additional, Matos, Tadeja, additional, Mikulska, Malgorzata, additional, Narayanan, Manjusha, additional, Martín-Pérez, Sonia, additional, Prattes, Juergen, additional, Rogers, Benedict, additional, Rahimli, Laman, additional, Ruiz, Maite, additional, Roilides, Emmanuel, additional, Samarkos, Michael, additional, Scharmann, Ulrike, additional, Sili, Uluhan, additional, Sipahi, Oguz Resat, additional, Sivakova, Alena, additional, Steinmann, Joerg, additional, Trauth, Janina, additional, Turhan, Ozge, additional, Van Praet, Jens, additional, Vena, Antonio, additional, White, P Lewis, additional, Willinger, Birgit, additional, Tortorano, Anna Maria, additional, Arendrup, Maiken C, additional, Koehler, Philipp, additional, Cornely, Oliver A, additional, Tumbarello, Mario, additional, Talento, Alida Fe, additional, Ruiz, Alba C, additional, Racil, Zdenek, additional, Stoma, Igor, additional, Calbacho, Maria, additional, Van Wijngaerden, Eric, additional, Henriques, Júlia, additional, Jordan, Harriett, additional, Ferroni, Valentina, additional, Ozyurt, Ozlem Koyuncu, additional, Milacek, Christopher, additional, Krause, Robert, additional, Zurl, Christoph, additional, Backx, Matthijs, additional, Li, Ang, additional, Seufert, Raphael, additional, Tomazin, Rok, additional, Blankenheim, Yael, additional, Dávila-Valls, Julio, additional, García-Clemente, Paloma, additional, Freiberger, Tomas, additional, Buil, Jochem, additional, Meis, Jacques F, additional, Akyol, Deniz, additional, Guegan, Hélène, additional, and Logan, Clare, additional

Published
2023
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23. Rezafungin versus caspofungin for treatment of candidaemia and invasive candidiasis (ReSTORE): a multicentre, double-blind, double-dummy, randomised phase 3 trial

Author

Thompson, George R, primary, Soriano, Alex, additional, Cornely, Oliver A, additional, Kullberg, Bart Jan, additional, Kollef, Marin, additional, Vazquez, Jose, additional, Honore, Patrick M, additional, Bassetti, Matteo, additional, Pullman, John, additional, Chayakulkeeree, Methee, additional, Poromanski, Ivan, additional, Dignani, Cecilia, additional, Das, Anita F, additional, Sandison, Taylor, additional, Pappas, Peter G, additional, Akova, Murat, additional, AlAgha, Rawan, additional, Alangaden, George, additional, Albrecht, Svenja J, additional, Alexander, Barbara, additional, Al-Obaidi, Mohanad, additional, Ambasch, German, additional, Armestar Rodriguez, Fernando, additional, Azap, Alpay, additional, Baffoe-Bonnie, Anthony, additional, Belkhir, Leila, additional, Ben-Ami, Ronen, additional, Boutoille, David, additional, Cascio, Antonio, additional, Chai, Louis YA, additional, Chaiwarith, Romanee, additional, Chen, Sharon, additional, Chen, Yee-Chun, additional, Chen, Yen-Hsu, additional, Choi, Jun Yong, additional, Choi, Young Hwa, additional, Chotiprasitsakul, Darunee, additional, Chung, Jin Won, additional, Danion, François, additional, Denis, Blandine, additional, Diaz Santos, Emilio, additional, Dictar, Miguel O, additional, Diltoer, Marc, additional, Dupont, Herve, additional, Feng, Sizhou, additional, Ferre Colomer, Maria Angeles, additional, Ferrer, Ricard, additional, Forel, Jean-Marie Fernand Roger, additional, Fortún-Abete, Jesús, additional, Garcia-Diaz, Julia, additional, Girardis, Massimo, additional, He, Fang, additional, Hites, Maya, additional, Ho, Mao-Wang, additional, Honore, Patrick, additional, Horcajada Gallego, Juan Pablo, additional, Huang, Haihui, additional, Huang, Po-Yen, additional, Huang, Yong, additional, Hussein, Osamah, additional, Intalapaporn, Poj, additional, Jaruratanasirikul, Sutep, additional, Jauregui-Peredo, Luis, additional, Johnson, Misty, additional, Jung, Dong Sik, additional, Jutivorakool, Kamonwan, additional, Kern, Winfried V, additional, Kett, Daniel H, additional, Khawcharoenporn, Thana, additional, Kim, Young Keun, additional, Koehler, Philipp, additional, Kotanidou, Anastasia, additional, Lachiewicz, Anne, additional, Lin, Qinhan, additional, Lopez Cortes, Luis Eduardo, additional, Luo, Hong, additional, Luzzati, Roberto, additional, Maor, Yasmin, additional, McCarty, Todd, additional, Merelli, Maria, additional, Merino Amador, Paloma, additional, Midturi, John, additional, Migliorino, Guglielmo Marco, additional, Mira, Jean-Paul, additional, Mootsikapun, Piroon, additional, Morrissey, Orla, additional, Munoz Garcia de Paredes, Patricia, additional, Mussini, Cristina, additional, Mylonakis, Eleftherios, additional, Nseir, Saadalla, additional, Nseir, William, additional, Odabasi, Zekaver, additional, Papastamopoulos, Vasileios, additional, Paterson, David, additional, Patterson, Thomas F, additional, Peck, Kyong Ran, additional, Peng, Zhiyong, additional, Permpalung, Nitipong, additional, Plantefeve, Gaetan J, additional, Poromanski, Ivan G, additional, Powell, Debra, additional, Psichogiou, Mina, additional, Puah, Ser Hon, additional, Rahav, Galia, additional, Martinez, Antonio Ramos, additional, Ramos Ramos, Juan Carlos, additional, Raz-Pasteur, Ayelet, additional, Restrepo Castro, Carlos A, additional, Riera, Fernando, additional, Roblot, France, additional, Rodriguez Alvarez, Regino Jose, additional, Rogers, Benjamin, additional, Roilides, Emmanuel, additional, Sanchez Vallejo, Gregorio, additional, Sganga, Gabriele, additional, Sipsas, Nikolaos, additional, Slavin, Monica, additional, Spec, Andrej, additional, Strahilevitz, Jacob, additional, Tancheva, Dora M, additional, Tao, Zhen, additional, Teschner, Daniel, additional, Thompson, George R, additional, Van Wijngaerden, Eric, additional, Vergidis, Paschalis, additional, Viale, Pierluigi, additional, Wang, Fu-Der, additional, Wang, Shifu, additional, Weber, Gabriel, additional, Weng, Jianyu, additional, Xu, Jinfu, additional, Yao, Li, additional, Yavuz, Serap, additional, Yilmaz, Mesut, additional, Young, Jo-Anne, additional, Zarate, Abel H, additional, Zeng, Jun, additional, and Zhang, Yong, additional

Published
2023
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24. Nocardia Infection in Solid Organ Transplant Recipients: A Multicenter European Case-control Study

Author

European Study Group for Nocardia in Solid Organ Transplantation, Coussement, Julien, Lebeaux, David, van Delden, Christian, Guillot, Hẻlẻne, Freund, Romain, Marbus, Sierk, Melica, Giovanna, Van Wijngaerden, Eric, Douvry, Benoit, Van Laecke, Steven, Vuotto, Fanny, Tricot, Leϊla, Fernández-Ruiz, Mario, Dantal, Jacques, Hirzel, Cẻdric, Jais, Jean-Philippe, Rodriguez-Nava, Veronica, Lortholary, Olivier, and Jacobs, Frédérique

Published
2016

26. Modulation of thromboinflammation in hospitalized COVID‐19 patients with aprotinin, low molecular weight heparin, and anakinra: The DAWn‐Antico study

Author

Engelen, Matthias M., primary, Van Thillo, Quentin, additional, Betrains, Albrecht, additional, Gyselinck, Iwein, additional, Martens, Caroline P., additional, Spalart, Valérie, additional, Ockerman, Anna, additional, Devooght, Caroline, additional, Wauters, Joost, additional, Gunst, Jan, additional, Wouters, Carine, additional, Vandenbriele, Christophe, additional, Rex, Steffen, additional, Liesenborghs, Laurens, additional, Wilmer, Alexander, additional, Meersseman, Philippe, additional, Van den Berghe, Greet, additional, Dauwe, Dieter, additional, Belmans, Ann, additional, Thomeer, Michiel, additional, Fivez, Tom, additional, Mesotten, Dieter, additional, Ruttens, David, additional, Heytens, Luc, additional, Dapper, Ilse, additional, Tuyls, Sebastiaan, additional, De Tavernier, Brecht, additional, Verhamme, Peter, additional, Vanassche, Thomas, additional, Van Wijngaerden, Eric, additional, Janssens, Wim, additional, Meyfroidt, Geert, additional, Vos, Robin, additional, Devos, Timothy, additional, De Munter, Paul, additional, Neyts, Johan, additional, Dupont, Lieven, additional, Spriet, Isabel, additional, Verbeke, Geert, additional, Claes, Kathleen, additional, Robberecht, Wim, additional, Van Geet, Chris, additional, Debaveye, Barbara, additional, Ceunen, Helga, additional, Servaes, Veerle, additional, Cludts, Katrien, additional, Vanheule, Kristine, additional, Jacobs, Cato, additional, Roebroek, Daimy, additional, Dreesen, Paulien, additional, Smet, Nele, additional, Dolhain, Jan, additional, Hoppenbrouwers, Mieke, additional, Wens, Kathleen, additional, Daems, Kristel, additional, and D’hondt, Monique, additional

Published
2022
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31. Lessons in Developing a Full-Genome Next-Generation Sequencing Pipeline for Molecular Epidemiology of Hcv

Author

Christensen, Kasper Thorhauge, primary, Pierard, Florian, additional, Schrooten, Yoeri, additional, Bonsall, David, additional, Bowden, Rory, additional, Simmonds, Peter, additional, Dierckx, Tim, additional, Nevens, Frederik, additional, Van Wijngaerden, Eric, additional, Robaeys, Geert, additional, Florence, Eric, additional, Vandamme, Anne-Mieke, additional, Cuypers, Lize, additional, and Van Laethem, Kristel, additional

Published
2022
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36. Long-term safety and efficacy of rilpivirine in combination with nucleoside/nucleotide reverse transcriptase inhibitors in HIV-1 infected patients: 336-week rollover study of phase 2b and 3 clinical studies

Author

Molina, Jean Michel, primary, Ene, Luminita, additional, Cahn, Pedro, additional, Fätkenheuer, Gerd, additional, Van Wijngaerden, Eric, additional, Lombaard, Johan, additional, Zakharova, Natalia, additional, Van Eygen, Veerle, additional, Vanveggel, Simon, additional, and Van Solingen-Ristea, Rodica, additional

Published
2021
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37. Corrigendum to “itraconazole for COVID-19: Preclinical studies and a proof-of-concept randomized clinical trial Laurens”

Author

Liesenborghs, Laurens, primary, Spriet, Isabel, additional, Jochmans, Dirk, additional, Belmans, Ann, additional, Gyselinck, Iwein, additional, Teuwen, Laure-Anne, additional, ter Horst, Sebastiaan, additional, Dreesen, Erwin, additional, Geukens, Tatjana, additional, Engelen, Matthias M., additional, Landeloos, Ewout, additional, Geldhof, Vincent, additional, Ceunen, Helga, additional, Debaveye, Barbara, additional, Vandenberk, Bert, additional, Van der Linden, Lorenz, additional, Jacobs, Sofie, additional, Langendries, Lana, additional, Boudewijns, Robbert, additional, Dan Do, Thuc Nguyen, additional, Chiu, Winston, additional, Wang, Xinyu, additional, Zhang, Xin, additional, Weynand, Birgit, additional, Vanassche, Thomas, additional, Devos, Timothy, additional, Meyfroidt, Geert, additional, Janssens, Wim, additional, Vos, Robin, additional, Vermeersch, Pieter, additional, Wauters, Joost, additional, Verbeke, Geert, additional, De Munter, Paul, additional, Kaptein, Suzanne J.F., additional, Rocha-Pereira, Joana, additional, Delang, Leen, additional, Van Wijngaerden, Eric, additional, Neyts, Johan, additional, and Verhamme, Peter, additional

Published
2021
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38. sj-pdf-1-avt-10.1177_13596535211062388 ��� Supplemental Material for Long-term safety and efficacy of rilpivirine in combination with nucleoside/nucleotide reverse transcriptase inhibitors in HIV-1-infected patients: 336-week rollover study of phase 2b and 3 clinical studies

Author

Molina, Jean Michel, Ene, Luminita, Cahn, Pedro, F��tkenheuer, Gerd, Van Wijngaerden, Eric, Lombaard, Johan, Zakharova, Natalia, Van Eygen, Veerle, Vanveggel, Simon, and Van Solingen-Ristea, Rodica

Subjects
FOS: Clinical medicine, 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
Abstract

Supplemental Material, sj-pdf-1-avt-10.1177_13596535211062388 for Long-term safety and efficacy of rilpivirine in combination with nucleoside/nucleotide reverse transcriptase inhibitors in HIV-1-infected patients: 336-week rollover study of phase 2b and 3 clinical studies by Jean Michel Molina, Luminita Ene, Pedro Cahn, Gerd F��tkenheuer, Eric Van Wijngaerden, Johan Lombaard, Natalia Zakharova, Veerle Van Eygen, Simon Vanveggel and Rodica Van Solingen-Ristea in Antiviral Therapy

Published
2021
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41. Comparison of changes in bone density and turnover with abacavir-lamivudine versus tenofovir-emtricitabine in HIV-infected adults: 48-week results from AASERT study

Author

Stellbrink, Hans-Jurgen, Orkin, Chloe, Arribas, Jose Ramon, Compston, Juiet, Gerstoft, Jan, Van Wijngaerden, Eric, Lazzarin, Adriano, Rizzardini, Giuliano, Sprenger, Herman G., Lambert, John, Sture, Gunta, Leather, David, Hughes, Sara, Zucchi, Patrizia, and Pearce, Helen

Subjects
Drug therapy, Combination -- Safety and security measures, Drug therapy, Combination -- Research, Antiviral agents -- Dosage and administration, Antiviral agents -- Complications and side effects, Antiviral agents -- Research, Highly active antiretroviral therapy -- Patient outcomes, Highly active antiretroviral therapy -- Demographic aspects, Highly active antiretroviral therapy -- Research, Bones -- Density, Bones -- Comparative analysis, Bones -- Demographic aspects, Health, Health care industry
Published
2010

42. Successful double-lung transplantation from a donor previously infected with SARS-CoV-2

Author

Ceulemans, Laurens J, primary, Van Slambrouck, Jan, additional, De Leyn, Paul, additional, Decaluwé, Herbert, additional, Van Veer, Hans, additional, Depypere, Lieven, additional, Ceuterick, Vincent, additional, Verleden, Stijn E, additional, Vanstapel, Arno, additional, Desmet, Stefanie, additional, Maes, Piet, additional, Van Ranst, Marc, additional, Lormans, Piet, additional, Meyfroidt, Geert, additional, Neyrinck, Arne P, additional, Vanaudenaerde, Bart M, additional, Van Wijngaerden, Eric, additional, Bos, Saskia, additional, Godinas, Laurent, additional, Carmeliet, Peter, additional, Verleden, Geert M, additional, Van Raemdonck, Dirk E, additional, and Vos, Robin, additional

Published
2021
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43. Diagnostic value of different adherence measures using electronic monitoring and virologic failure as reference standards

Author

Deschamps, Ann E., De Geest, Sabina, Vandamme, Anne-Mieke, Bobbaers, Herman, Peetermans, Willy E., and Van Wijngaerden, Eric

Subjects
AIDS treatment -- Standards, HIV infection -- Care and treatment, Highly active antiretroviral therapy -- Standards, Health
Abstract

Nonadherence to antiretroviral therapy is a substantial problem in HIV and jeopardizes the success of treatment. Accurate measurement of nonadherence is therefore imperative for good clinical management but no gold standard has been agreed on yet. In a single-center prospective study nonadherence was assessed by electronic monitoring: percentage of doses missed and drug holidays and by three self reports: (1) a visual analogue scale (VAS): percentage of overall doses taken; (2) the Swiss HIV Cohort Study Adherence Questionnaire (SHCS-AQ): percentage of overall doses missed and drug holidays and (3) the European HIV Treatment Questionnaire (EHTQ): percentage of doses missed and drug holidays for each antiretroviral drug separately. Virologic failure prospectively assessed during 1 year, and electronic monitoring were used as reference standards. Using virologic failure as reference standard, the best results were for (1) the SHCS-AQ after electronic monitoring (sensitivity, 87.5%; specificity, 78.6%); (2) electronic monitoring (sensitivity, 75%; specificity, 85.6%), and (3) the VAS combined with the SHCS-AQ before electronic monitoring (sensitivity, 87.5%; specificity, 58.6%). The sensitivity of the complex EHTQ was less than 50%. Asking simple questions about doses taken or missed is more sensitive than complex questioning about each drug separately. Combining the VAS with the SHCS-AQ seems a feasible nonadherence measure for daily clinical practice. Self-reports perform better after electronic monitoring: their diagnostic value could be lower when given independently.

Published
2008

44. Invasive aspergillosis in the intensive care unit

Author

Meersseman, Wouter, Lagrou, Katrien, Maertens, Johan, and Van Wijngaerden, Eric

Subjects
Aspergillosis -- Diagnosis, Aspergillosis -- Risk factors, Aspergillosis -- Research, Intensive care units -- Research, Health, Health care industry
Published
2007

46. Immunogenicity and Safety of the 9-Valent Human Papillomavirus Vaccine in Solid Organ Transplant Recipients and Adults Infected With Human Immunodeficiency Virus (HIV)

Author

Boey, Lise, primary, Curinckx, Ans, additional, Roelants, Mathieu, additional, Derdelinckx, Inge, additional, Van Wijngaerden, Eric, additional, De Munter, Paul, additional, Vos, Robin, additional, Kuypers, Dirk, additional, Van Cleemput, Johan, additional, and Vandermeulen, Corinne, additional

Published
2020
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47. Global and regional epidemiology of HIV-1 recombinants in 1990–2015: a systematic review and global survey

Author

Hemelaar, Joris, primary, Elangovan, Ramyiadarsini, additional, Yun, Jason, additional, Dickson-Tetteh, Leslie, additional, Kirtley, Shona, additional, Gouws-Williams, Eleanor, additional, Ghys, Peter D, additional, Abimiku, Alash'le G, additional, Agwale, Simon, additional, Archibald, Chris, additional, Avidor, Boaz, additional, Barbás, María Gabriela, additional, Barre-Sinoussi, Francoise, additional, Barugahare, Banson, additional, Belabbes, El Hadj, additional, Bertagnolio, Silvia, additional, Birx, Deborah, additional, Bobkov, Aleksei F, additional, Brandful, James, additional, Bredell, Helba, additional, Brennan, Catherine A, additional, Brooks, James, additional, Bruckova, Marie, additional, Buonaguro, Luigi, additional, Buonaguro, Franco, additional, Buttò, Stefano, additional, Buvé, Anne, additional, Campbell, Mary, additional, Carr, Jean, additional, Carrera, Alex, additional, Carrillo, Manuel Gómez, additional, Celum, Connie, additional, Chaplin, Beth, additional, Charles, Macarthur, additional, Chatzidimitriou, Dimitrios, additional, Chen, Zhiwei, additional, Chijiwa, Katsumi, additional, Cooper, David, additional, Cunningham, Philip, additional, Dagnra, Anoumou, additional, de Gascun, Cillian F, additional, Del Amo, Julia, additional, Delgado, Elena, additional, Dietrich, Ursula, additional, Dwyer, Dominic, additional, Ellenberger, Dennis, additional, Ensoli, Barbara, additional, Essex, Max, additional, Gao, Feng, additional, Fleury, Hervé, additional, Fonjungo, Peter N, additional, Foulongne, Vincent, additional, Gadkari, Deepak A, additional, García, Federico, additional, Garsia, Roger, additional, Gershy-Damet, Guy Michel, additional, Glynn, Judith R, additional, Goodall, Ruth, additional, Grossman, Zehava, additional, Lindenmeyer-Guimarães, Monick, additional, Hahn, Beatrice, additional, Hamers, Raph L, additional, Hamouda, Osamah, additional, Handema, Ray, additional, He, Xiang, additional, Herbeck, Joshua, additional, Ho, David D, additional, Holguin, Africa, additional, Hosseinipour, Mina, additional, Hunt, Gillian, additional, Ito, Masahiko, additional, Bel Hadj Kacem, Mohamed Ali, additional, Kahle, Erin, additional, Kaleebu, Pontiano, additional, Kalish, Marcia, additional, Kamarulzaman, Adeeba, additional, Kang, Chun, additional, Kanki, Phyllis, additional, Karamov, Edward, additional, Karasi, Jean-Claude, additional, Kayitenkore, Kayitesi, additional, Kelleher, Tony, additional, Kitayaporn, Dwip, additional, Kostrikis, Leondios G, additional, Kucherer, Claudia, additional, Lara, Claudia, additional, Leitner, Thomas, additional, Liitsola, Kirsi, additional, Lingappa, Jai, additional, Linka, Marek, additional, Lorenzana de Rivera, Ivette, additional, Lukashov, Vladimir, additional, Maayan, Shlomo, additional, Mayr, Luzia, additional, McCutchan, Francine, additional, Meda, Nicolas, additional, Menu, Elisabeth, additional, Mhalu, Fred, additional, Mloka, Doreen, additional, Mokili, John L, additional, Montes, Brigitte, additional, Mor, Orna, additional, Morgado, Mariza, additional, Mosha, Fausta, additional, Moussi, Awatef, additional, Mullins, James, additional, Najera, Rafael, additional, Nasr, Mejda, additional, Ndembi, Nicaise, additional, Neilson, Joel R, additional, Nerurkar, Vivek R, additional, Neuhann, Florian, additional, Nolte, Claudine, additional, Novitsky, Vlad, additional, Nyambi, Philippe, additional, Ofner, Marianna, additional, Paladin, Fem J, additional, Papa, Anna, additional, Pape, Jean, additional, Parkin, Neil, additional, Parry, Chris, additional, Peeters, Martine, additional, Pelletier, Alexandra, additional, Pérez-Álvarez, Lucía, additional, Pillay, Deenan, additional, Pinto, Angie, additional, Quang, Trinh Duy, additional, Rademeyer, Cecilia, additional, Raikanikoda, Filimone, additional, Rayfield, Mark A, additional, Reynes, Jean-Marc, additional, Rinke de Wit, Tobias, additional, Robbins, Kenneth E, additional, Rolland, Morgane, additional, Rousseau, Christine, additional, Salazar-Gonzales, Jesus, additional, Salem, Hanan, additional, Salminen, Mika, additional, Salomon, Horacio, additional, Sandstrom, Paul, additional, Santiago, Mario L, additional, Sarr, Abdoulaye D, additional, Schroeder, Bryan, additional, Segondy, Michel, additional, Selhorst, Philippe, additional, Sempala, Sylvester, additional, Servais, Jean, additional, Shaik, Ansari, additional, Shao, Yiming, additional, Slim, Amine, additional, Soares, Marcelo A, additional, Songok, Elijah, additional, Stewart, Debbie, additional, Stokes, Julie, additional, Subbarao, Shambavi, additional, Sutthent, Ruengpung, additional, Takehisa, Jun, additional, Tanuri, Amilcar, additional, Tee, Kok Keng, additional, Thapa, Kiran, additional, Thomson, Michael, additional, Tran, Tyna, additional, Urassa, Willy, additional, Ushijima, Hiroshi, additional, van de Perre, Philippe, additional, van der Groen, Guido, additional, van Laethem, Kristel, additional, van Oosterhout, Joep, additional, van Sighem, Ard, additional, van Wijngaerden, Eric, additional, Vandamme, Anne-Mieke, additional, Vercauteren, Jurgen, additional, Vidal, Nicole, additional, Wallace, Lesley, additional, Williamson, Carolyn, additional, Wolday, Dawit, additional, Xu, Jianqing, additional, Yang, Chunfu, additional, Zhang, Linqi, additional, and Zhang, Rong, additional

Published
2020
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48. Prevalence and correlates of nonadherence to antiretroviral therapy in a population of HIV patients using medication event monitoring system[R]

Author

Deschamps, Ann E., De Graeve, Veerle, Van Wijngaerden, Eric, De Saar, Veerle, Vandamme, Anne-Mieke, Van Vaerenbergh, Kristien, Ceunen, Helga, Bobbaers, Herman, Peetermans, Willy E., De Vleeschouwer, Peter J., and De Geest, Sabina

Subjects
Highly active antiretroviral therapy -- Health aspects, HIV patients -- Drug therapy, Antiviral agents -- Dosage and administration, Health
Abstract

Nonadherence to antiretroviral therapy (ART) jeopardizes good clinical outcome in people living with HIV. In a single-center prospective study, prevalence and correlates of nonadherence were investigated in 43 patients on ART. Nonadherence was assessed using Medication Event Monitoring System[R] (MEMS[R]), self-report and collateral report of treating physicians. Based on MEMS[R] data, median taking adherence, dosing adherence, and timing adherence was 98% (interquartile range [IQR] = 5.3), 91.5% (IQR = 18), and 86% (IQR = 31.5), respectively. The median number of drug holidays per 100 days was 0.8 (IQR = 4.8). The prevalence of nonadherence measured by MEMS[R] was 40%. Self-reported nonadherence and collateral report of nonadherence by physicians varied from 5% to 41% and 24% to 28%, respectively. Patients were categorized as adherent or nonadherent based on a clinically validated algorithm derived from MEMS[R] parameters. Nonadherent patients used significantly more escaping coping strategies (p = 0.003) and planned problem solving strategies (p = 0.049), were prescribed significantly more antiretroviral medications (p = 0.02) and were significantly longer on ART (p = 0.04) than adherent patients. Identified correlates of nonadherence may help clinicians in detecting patients with HIV at risk for nonadherence and can support the development of adherence enhancing interventions.

Published
2004

49. RegaDB: community-driven data management and analysis for infectious diseases

Author

Libin, Pieter, Beheydt, Gertjan, Deforche, Koen, Imbrechts, Stijn, Ferreira, Fossie, Van Laethem, Kristel, Theys, Kristof, Carvalho, Ana Patricia, Cavaco-Silva, Joana, Lapadula, Giuseppe, Torti, Carlo, Assel, Matthias, Wesner, Stefan, Snoeck, Joke, Ruelle, Jean, De Bel, Annelies, Lacor, Patrick, De Munter, Paul, Van Wijngaerden, Eric, Zazzi, Maurizio, Kaiser, Rolf, Ayouba, Ahidjo, Peeters, Martine, de Oliveira, Tulio, Alcantara, Luiz C. J., Grossman, Zehava, Sloot, Peter, Otelea, Dan, Paraschiv, Simona, Boucher, Charles, Camacho, Ricardo J., and Vandamme, Anne-Mieke

Published
2013
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