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12 results on '"van den Hengel-Koot, Irma"'

1. The INTOXICATE study: methodology and preliminary results of a prospective observational study

Author

Zwaag, Samanta M., van den Hengel-Koot, Irma S., Baker, Stuart, Druwé, Patrick, Elhadi, Muhammed, Dufol, Ana Ferrer, Forsberg, Sune, Halacli, Burcin, Jung, Christian, Laubner Sakalauskienė, Gabija, Lindqvist, Elin, Moreno, Rui, Rabe, Christian, Reiter, Nanna, Rezar, Richard, Țincu, Radu, Topeli, Arzu, Wood, David M., de Lange, Dylan W., and Hunault, Claudine C.

Published
2024
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2. Clinical effects of cannabis compared to synthetic cannabinoid receptor agonists (SCRAs): a retrospective cohort study of presentations with acute toxicity to European hospitals between 2013 and 2020

Author

NVIC bedrijfsvoering, Brain, Waters, Mitchell L., Dargan, Paul I., Yates, Christopher, Dines, Alison M., Eyer, Florian, Giraudon, Isabelle, Heyerdahl, Fridtjof, Hovda, Knut Erik, Liechti, Matthias E., Miró, Òscar, Vallersnes, Odd Martin, Anseeuw, Kurt, Badaras, Robertas, Bitel, Marcin, Bonnici, Jeffrey, Brvar, Miran, Caganova, Blazena, Calýskan, Feriyde, Ceschi, Alessandro, Chamoun, Karam, Daveloose, Laurence, Galicia, Miguel, Gartner, Birgit, Gorozia, Ketevan, Grenc, Damjan, Gresnigt, Femke M.J., Hondebrink, Laura, Jürgens, Gesche, Konstari, Jutta, Kutubidze, Soso, Laubner, Gabija, Liakoni, Evangelia, Liguts, Viesturs, Lyphout, Cathelijne, McKenna, Roy, Mégarbane, Bruno, Moughty, Adrian, Nitescu, Gabriela Viorela, Noseda, Roberta, O'Connor, Niall, Paasma, Raido, Ortega Perez, Juan, Perminas, Marius, Persett, Per Sverre, Põld, Kristiina, Puchon, Erik, Puiguriguer, Jordi, Radenkova-Saeva, Julia, Rulisek, Jan, Samer, Caroline, Schmid, Yasmin, Scholz, Irene, Stašinskis, Roberts, Surkus, Jonas, Van den Hengel-Koot, Irma, Vigorita, Federico, Vogt, Severin, Waldman, Wojciech, Waring, William Stephen, Zacharov, Sergej, Zellner, Tobias, Wood, David M., NVIC bedrijfsvoering, Brain, Waters, Mitchell L., Dargan, Paul I., Yates, Christopher, Dines, Alison M., Eyer, Florian, Giraudon, Isabelle, Heyerdahl, Fridtjof, Hovda, Knut Erik, Liechti, Matthias E., Miró, Òscar, Vallersnes, Odd Martin, Anseeuw, Kurt, Badaras, Robertas, Bitel, Marcin, Bonnici, Jeffrey, Brvar, Miran, Caganova, Blazena, Calýskan, Feriyde, Ceschi, Alessandro, Chamoun, Karam, Daveloose, Laurence, Galicia, Miguel, Gartner, Birgit, Gorozia, Ketevan, Grenc, Damjan, Gresnigt, Femke M.J., Hondebrink, Laura, Jürgens, Gesche, Konstari, Jutta, Kutubidze, Soso, Laubner, Gabija, Liakoni, Evangelia, Liguts, Viesturs, Lyphout, Cathelijne, McKenna, Roy, Mégarbane, Bruno, Moughty, Adrian, Nitescu, Gabriela Viorela, Noseda, Roberta, O'Connor, Niall, Paasma, Raido, Ortega Perez, Juan, Perminas, Marius, Persett, Per Sverre, Põld, Kristiina, Puchon, Erik, Puiguriguer, Jordi, Radenkova-Saeva, Julia, Rulisek, Jan, Samer, Caroline, Schmid, Yasmin, Scholz, Irene, Stašinskis, Roberts, Surkus, Jonas, Van den Hengel-Koot, Irma, Vigorita, Federico, Vogt, Severin, Waldman, Wojciech, Waring, William Stephen, Zacharov, Sergej, Zellner, Tobias, and Wood, David M.

Published
2024

4. High Incidence of Signs of Neuropathy and Self-Reported Substance Use Disorder for Nitrous Oxide in Patients Intoxicated with Nitrous Oxide

Author

NVIC, Other research (not in main researchprogram), Medische Staf Intensive Care, NVIC bedrijfsvoering, Brain, Infection & Immunity, Nugteren-Van Lonkhuyzen, Johanna J, van der Ben, Lot, van den Hengel-Koot, Irma S, de Lange, Dylan W, van Riel, Antoinette J H P, Hondebrink, Laura, NVIC, Other research (not in main researchprogram), Medische Staf Intensive Care, NVIC bedrijfsvoering, Brain, Infection & Immunity, Nugteren-Van Lonkhuyzen, Johanna J, van der Ben, Lot, van den Hengel-Koot, Irma S, de Lange, Dylan W, van Riel, Antoinette J H P, and Hondebrink, Laura

Published
2023

6. Predicting hypertension using subjective symptoms in recreational drug users at first-aid stations at dance events

Author

NVIC, Brain, Other research (not in main researchprogram), NVIC bedrijfsvoering, MS Interne Geneeskunde, Prins, Yoram P., Hondebrink, Laura, van den Hengel-Koot, Irma S., Litsenburg, Ronald, Dekker, Douwe, NVIC, Brain, Other research (not in main researchprogram), NVIC bedrijfsvoering, MS Interne Geneeskunde, Prins, Yoram P., Hondebrink, Laura, van den Hengel-Koot, Irma S., Litsenburg, Ronald, and Dekker, Douwe

Published
2021

7. Frequent hospitalization for synthetic cathinone poisonings: a case series reported to the Dutch Poisons Information Center

Author

NVIC bedrijfsvoering, Other research (not in main researchprogram), Medische Staf Intensive Care, Brain, Infection & Immunity, Nugteren-van Lonkhuyzen, Johanna J., Rietjens, Saskia J., van Riel, Antoinette J. H. P., van den Hengel-Koot, Irma S., Contrucci, Ramon R., de Lange, Dylan W., Hondebrink, Laura, NVIC bedrijfsvoering, Other research (not in main researchprogram), Medische Staf Intensive Care, Brain, Infection & Immunity, Nugteren-van Lonkhuyzen, Johanna J., Rietjens, Saskia J., van Riel, Antoinette J. H. P., van den Hengel-Koot, Irma S., Contrucci, Ramon R., de Lange, Dylan W., and Hondebrink, Laura

Published
2021

8. A quarter of admitted poisoned patients have a mild poisoning and require no treatment : An observational study

Author

Hondebrink, L., Rietjens, Saskia J., Donker, Dirk W., Hunault, Claudine C., van den Hengel-Koot, Irma, Verputten, Pauline M., de Vries, Irma, Kaasjager, Karin A.H., Dekker, D., de Lange, Dylan W., Hondebrink, L., Rietjens, Saskia J., Donker, Dirk W., Hunault, Claudine C., van den Hengel-Koot, Irma, Verputten, Pauline M., de Vries, Irma, Kaasjager, Karin A.H., Dekker, D., and de Lange, Dylan W.

Published
2019

9. A quarter of admitted poisoned patients have a mild poisoning and require no treatment: An observational study

Author

UMC Utrecht, NVIC, Other research (not in main researchprogram), Medische Staf Intensive Care, MS Interne Geneeskunde, Circulatory Health, NVIC bedrijfsvoering, Infection & Immunity, Hondebrink, L., Rietjens, Saskia J., Donker, Dirk W., Hunault, Claudine C., van den Hengel-Koot, Irma, Verputten, Pauline M., de Vries, Irma, Kaasjager, Karin A.H., Dekker, D., de Lange, Dylan W., UMC Utrecht, NVIC, Other research (not in main researchprogram), Medische Staf Intensive Care, MS Interne Geneeskunde, Circulatory Health, NVIC bedrijfsvoering, Infection & Immunity, Hondebrink, L., Rietjens, Saskia J., Donker, Dirk W., Hunault, Claudine C., van den Hengel-Koot, Irma, Verputten, Pauline M., de Vries, Irma, Kaasjager, Karin A.H., Dekker, D., and de Lange, Dylan W.

Published
2019

10. TOXIC study: exposures and outcome of intoxicated patients visiting the emergency department

Author

Hondebrink, Laura, Rietjens, Saskia R., Van Den Hengel-Koot, Irma, Zandee, Bianka, Strik, Jeffrey, De Lange, Dylan W., Kaasjager, Karin A. H., Dekker, Douwe, Meulenbelt, Jan, Hondebrink, Laura, Rietjens, Saskia R., Van Den Hengel-Koot, Irma, Zandee, Bianka, Strik, Jeffrey, De Lange, Dylan W., Kaasjager, Karin A. H., Dekker, Douwe, and Meulenbelt, Jan

Published
2016

11. TOXIC study: exposures and outcome of intoxicated patients visiting the emergency department

Author

NVIC, Other research (not in main researchprogram), Medische Staf Intensive Care, MS Interne Geneeskunde, Circulatory Health, Hondebrink, Laura, Rietjens, Saskia R., Van Den Hengel-Koot, Irma, Zandee, Bianka, Strik, Jeffrey, De Lange, Dylan W., Kaasjager, Karin A. H., Dekker, Douwe, Meulenbelt, Jan, NVIC, Other research (not in main researchprogram), Medische Staf Intensive Care, MS Interne Geneeskunde, Circulatory Health, Hondebrink, Laura, Rietjens, Saskia R., Van Den Hengel-Koot, Irma, Zandee, Bianka, Strik, Jeffrey, De Lange, Dylan W., Kaasjager, Karin A. H., Dekker, Douwe, and Meulenbelt, Jan

Published
2016

12. Clinical effects of cannabis compared to synthetic cannabinoid receptor agonists (SCRAs): a retrospective cohort study of presentations with acute toxicity to European hospitals between 2013 and 2020.

Author

Waters ML, Dargan PI, Yates C, Dines AM, Eyer F, Giraudon I, Heyerdahl F, Hovda KE, Liechti ME, Miró Ò, Vallersnes OM, Anseeuw K, Badaras R, Bitel M, Bonnici J, Brvar M, Caganova B, Calýskan F, Ceschi A, Chamoun K, Daveloose L, Galicia M, Gartner B, Gorozia K, Grenc D, Gresnigt FMJ, Hondebrink L, Jürgens G, Konstari J, Kutubidze S, Laubner G, Liakoni E, Liguts V, Lyphout C, McKenna R, Mégarbane B, Moughty A, Nitescu GV, Noseda R, O'Connor N, Paasma R, Ortega Perez J, Perminas M, Persett PS, Põld K, Puchon E, Puiguriguer J, Radenkova-Saeva J, Rulisek J, Samer C, Schmid Y, Scholz I, Stašinskis R, Surkus J, Van den Hengel-Koot I, Vigorita F, Vogt S, Waldman W, Waring WS, Zacharov S, Zellner T, and Wood DM

Subjects
Humans, Retrospective Studies, Male, Female, Europe epidemiology, Adult, Middle Aged, Young Adult, Cannabis toxicity, Cannabinoids toxicity, Adolescent, Cannabinoid Receptor Agonists toxicity, Emergency Service, Hospital
Abstract

Introduction: Cannabis is the most common recreational drug worldwide and synthetic cannabinoid receptor agonists are currently the largest group of new psychoactive substances. The aim of this study was to compare the clinical features and outcomes of lone acute cannabis toxicity with lone acute synthetic cannabinoid receptor agonist toxicity in a large series of presentations to European emergency departments between 2013-2020., Methods: Self-reported drug exposure, clinical, and outcome data were extracted from the European Drug Emergencies Network Plus which is a surveillance network that records data on drug-related emergency department presentations to 36 centres in 24 European countries. Cannabis exposure was considered the control in all analyses. To compare the lone cannabis and lone synthetic cannabinoid receptor agonist groups, univariate analysis using chi squared testing was used for categorical variables and non-parametric Mann-Whitney U- testing for continuous variables. Statistical significance was defined as a P value of <0.05., Results: Between 2013-2020 there were 54,314 drug related presentations of which 2,657 were lone cannabis exposures and 503 lone synthetic cannabinoid receptor agonist exposures. Synthetic cannabinoid receptor agonist presentations had statistically significantly higher rates of drowsiness, coma, agitation, seizures and bradycardia at the time of presentation. Cannabis presentations were significantly more likely to have palpitations, chest pain, hypertension, tachycardia, anxiety, vomiting and headache., Discussion: Emergency department presentations involving lone synthetic cannabinoid receptor agonist exposures were more likely to have neuropsychiatric features and be admitted to a psychiatric ward, and lone cannabis exposures were more likely to have cardiovascular features. Previous studies have shown variability in the acute toxicity of synthetic cannabinoid receptor agonists compared with cannabis but there is little comparative data available on lone exposures. There is limited direct comparison in the current literature between lone synthetic cannabinoid receptor agonist and lone cannabis exposure, with only two previous poison centre series and two clinical series. Whilst this study is limited by self-report being used to identify the drug(s) involved in the presentations, previous studies have demonstrated that self-report is reliable in emergency department presentations with acute drug toxicity., Conclusion: This study directly compares presentations with acute drug toxicity related to the lone use of cannabis or synthetic cannabinoid receptor agonists. It supports previous findings of increased neuropsychiatric toxicity from synthetic cannabinoid receptor agonists compared to cannabis and provides further data on cardiovascular toxicity in lone cannabis use.

Published
2024
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