Search

Your search keyword '"van den Hove, D.L.A."' showing total 29 results
Start Over Author "van den Hove, D.L.A."
29 results on '"van den Hove, D.L.A."'

10. Behavioral testing and litter effects in the rabbit

Author

Gümüş, H.G., primary, Agyemang, A.A., additional, Romantsik, O., additional, Sandgren, R., additional, Karlsson, H., additional, Gram, M., additional, Vallius, S., additional, Ley, D., additional, van den Hove, D.L.A., additional, and Bruschettini, M., additional

Published
2018
Full Text
View/download PDF

18. Recurrent long-lasting tethering reduces BDNF protein levels in the dorsal hippocampus and frontal cortex in pigs

Author

Emotion and Cognition, Dep Gezondheidszorg Landbouwhuisdieren, De Vry, J., Prickaerts, J., Jetten, M., Hulst, M., Steinbusch, H.W.M., van den Hove, D.L.A., Schuurman, T., van der Staay, F.J., Emotion and Cognition, Dep Gezondheidszorg Landbouwhuisdieren, De Vry, J., Prickaerts, J., Jetten, M., Hulst, M., Steinbusch, H.W.M., van den Hove, D.L.A., Schuurman, T., and van der Staay, F.J.

Published
2012

26. Prenatal stress and neonatal rat brain development

Author

Van den Hove, D.L.A., primary, Steinbusch, H.W.M., additional, Scheepens, A., additional, Van de Berg, W.D.J., additional, Kooiman, L.A.M., additional, Boosten, B.J.G., additional, Prickaerts, J., additional, and Blanco, C.E., additional

Published
2006
Full Text
View/download PDF

28. Fetal asphyxia leads to the loss of striatal presynaptic boutons in adult rats

Author

Strackx, E., Van den Hove, D.L.A., Steinbusch, H.P., Steinbusch, H.W.M., Vles, J.S.H., Blanco, C.E., and Gavilanes, A.W.D.

Subjects
*PRESYNAPTIC receptors, *LABORATORY rats, *DEVELOPMENTAL neurobiology, *PREFRONTAL cortex, *ASPHYXIA, *SYNAPSES, *ETIOLOGY of diseases, *NEUROMUSCULAR diseases
Abstract

Abstract: Fetal asphyxic insults in the brain are known to be associated with developmental and neurological problems like neuromotor disorders and cognitive deficits. Little is known, however, about the long-term consequences of fetal asphyxia contributing to the development of different neurological diseases common in the adult or the aging brain. For that reason the present study aimed to investigate the long-term effects of fetal asphyxia on synaptic organization within the adult rat brain. Fetal asphyxia was induced at embryonic day 17 by 75-min clamping of the uterine and ovarian arteries. Presynaptic bouton densities and numbers were analyzed in the striatum and prefrontal cortex at the age of 19 months. A substantial decrease in presynaptic bouton density and number was observed in the striatum of fetal asphyxia rats compared to control rats, while an increase was found in the fifth layer of the prefrontal cortex. These results suggest that fetal asphyxia can have long-lasting effects on synaptic organization that might contribute to a developmental etiology of different neurological disorders and aging. [Copyright &y& Elsevier]

Published
2010
Full Text
View/download PDF

29. Prenatal stress in the rat alters 5-HT1A receptor binding in the ventral hippocampus

Author

Van den Hove, D.L.A., Lauder, J.M., Scheepens, A., Prickaerts, J., Blanco, C.E., and Steinbusch, H.W.M.

Subjects
*PREGNANT women, *PSYCHOLOGICAL stress, *SEROTONIN, *AFFECTIVE disorders
Abstract

Abstract: Exposure of a pregnant woman to physical and/or psychological stress might affect her offspring by promoting the development of various learning, behavioral and/or mood disorders in later life. The 5-HT1A and 5-HT2A receptors are prominently implicated in the modulation of anxiety and mood-related behaviors. Using a semi-quantitative radiolabel immunocytochemical analysis (immunobinding), we studied the effect of prenatal stress on binding of these two receptor subtypes in the hippocampus of 4-week-old male and female Fischer 344 rats. Levels of 5-HT1A immunobinding in the ventral hippocampus, which is primarily implicated in emotional processing, were significantly decreased in male offspring after prenatal stress. A trend towards a decrease was observed in the ventral hippocampus of females. In contrast, 5-HT1A immunobinding within the dorsal hippocampus, which is mainly related to learning and memory, was not affected by prenatal stress in offspring of either gender. Likewise, no significant differences between control and prenatally stressed rats were observed for levels of 5-HT2A immunobinding in either part of the hippocampus or gender. The observed reduction in hippocampal 5-HT1A receptor binding in male offspring after prenatal stress may have important consequences for adult anxiety- and depressive-like behavior. [Copyright &y& Elsevier]

Published
2006
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results