513 results on '"van der Laan, Luc J. W."'
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2. An Organotypic Human Lymph Node Model Reveals the Importance of Fibroblastic Reticular Cells for Dendritic Cell Function
3. Cholangiocyte organoids to study drug-induced injury
4. Criteria for preclinical models of cholangiocarcinoma: scientific and medical relevance
5. Modelling immune cytotoxicity for cholangiocarcinoma with tumour-derived organoids and effector T cells
6. Unbiased method for spectral analysis of cells with great diversity of autofluorescence spectra
7. Deciphering potential implications of dietary microplastics for human health
8. Recapitulating lipid accumulation and related metabolic dysregulation in human liver-derived organoids
9. Kinome profiling of cholangiocarcinoma organoids reveals potential druggable targets that hold promise for treatment stratification
10. Gelatin-Based Hybrid Hydrogels as Matrices for Organoid Culture
11. The extracellular matrix as hallmark of cancer and metastasis: From biomechanics to therapeutic targets
12. An Organotypic Human Lymph Node Model Reveals the Importance of Fibroblastic Reticular Cells for Dendritic Cell Function
13. Evaluation of RNA isolation methods for microRNA quantification in a range of clinical biofluids
14. Precancerous liver diseases do not cause increased mutagenesis in liver stem cells
15. Long-term live imaging and multiscale analysis identify heterogeneity and core principles of epithelial organoid morphogenesis
16. HOXA13 in etiology and oncogenic potential of Barrett’s esophagus
17. A proof of concept study on real-time LiMAx CYP1A2 liver function assessment of donor grafts during normothermic machine perfusion
18. Drug repurposing screen identifies vidofludimus calcium and pyrazofurin as novel chemical entities for the development of hepatitis E interventions.
19. Biomarkers to Monitor Graft Function Following Liver Transplantation
20. LGR5 marks targetable tumor-initiating cells in mouse liver cancer
21. Human extrahepatic and intrahepatic cholangiocyte organoids show region-specific differentiation potential and model cystic fibrosis-related bile duct disease
22. Prime editing for functional repair in patient-derived disease models
23. Emerging organoid-immune co-culture models for cancer research: from oncoimmunology to personalized immunotherapies
24. Ultra-thin fluorocarbon foils optimise multiscale imaging of three-dimensional native and optically cleared specimens
25. Gene Therapies for Hepatitis C Virus
26. Drug Metabolism of Hepatocyte-like Organoids and Their Applicability in In Vitro Toxicity Testing
27. Toward Transplantation of Liver Organoids: From Biology and Ethics to Cost-effective Therapy
28. Donor‐specific anti‐HLA antibodies are not associated with nonanastomotic biliary strictures but both are independent risk factors for graft loss after liver transplantation
29. Characterization of donor and recipient CD8+ tissue-resident memory T cells in transplant nephrectomies
30. Deciphering potential implications of dietary microplastics for human health
31. Scalable Production of Size-Controlled Cholangiocyte and Cholangiocarcinoma Organoids within Liver Extracellular Matrix-Containing Microcapsules
32. Cholangiocarcinoma cell proliferation is enhanced in primary sclerosing cholangitis: A role for IL‐17A
33. Label-Free Imaging Analysis of Patient-Derived Cholangiocarcinoma Organoids after Sorafenib Treatment
34. A human kidney and liver organoid‐based multi‐organ‐on‐a‐chip model to study the therapeutic effects and biodistribution of mesenchymal stromal cell‐derived extracellular vesicles
35. Kupffer Cells Interact With Hepatitis B Surface Antigen In Vivo and In Vitro, Leading to Proinflammatory Cytokine Production and Natural Killer Cell Function
36. Letter to the Editor: The mucosal gut signature in primary sclerosing cholangitis before and after liver transplantation. Is the dysbiosis index really predictive for the recurrence of PSC?
37. Cholangiocarcinoma cell proliferation is enhanced in primary sclerosing cholangitis: A role for IL‐17A.
38. Human Cholangiocytes Form a Polarized and Functional Bile Duct on Hollow Fiber Membranes
39. Liver Ischemia and Reperfusion Induce Periportal Expression of Necroptosis Executor pMLKL Which Is Associated With Early Allograft Dysfunction After Transplantation
40. Assessment of human leukocyte antigen matching algorithm PIRCHE‐II on liver transplantation outcomes
41. Volumetric Bioprinting of Organoids and Optically Tuned Hydrogels to Build Liver‐Like Metabolic Biofactories (Adv. Mater. 15/2022)
42. Exosome-mediated transmission of hepatitis C virus between human hepatoma Huh7.5 cells
43. Mutations in BAP1 drive tumour sensitivity to programmed cell death in patient-derived cholangiocarcinoma orgnaoids
44. Modelling metastatic colonization of cholangiocarcinoma organoids in decellularized lung and lymph nodes.
45. Vitamin D Receptor Polymorphisms Are Associated with Reduced Esophageal Vitamin D Receptor Expression and Reduced Esophageal Adenocarcinoma Risk
46. Differential Sensitivities of Fast- and Slow-Cycling Cancer Cells to Inosine Monophosphate Dehydrogenase 2 Inhibition by Mycophenolic Acid
47. Design by Nature: Emerging Applications of Native Liver Extracellular Matrix for Cholangiocyte Organoid-Based Regenerative Medicine
48. Recapitulating hepatitis E virus–host interactions and facilitating antiviral drug discovery in human liver–derived organoids
49. Biomarkers to Monitor Graft Function Following Liver Transplantation
50. Bioprinting of Human Liver-derived Epithelial Organoids for Toxicity Studies
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