3,476 results on '"van der Meer, J"'
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2. Reduction by invariants, stratifications, foliations, fibrations and relative equilibria, a short survey
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van der Meer, J. C.
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Mathematics - Dynamical Systems ,53D20 (Primary), 58A35, 37C79 (Secondary) - Abstract
In this note we will consider reduction techniques for Hamiltonian systems that are invariant under the action of a compact Lie group $G$ acting by symplectic diffeomorphisms, and the related work on stability of relative equilibria. We will focus on reduction by invariants in which case it is possible to describe a reduced phase space within the orbit space by constructing an orbit map using a Hilbert basis of invariants for the symmetry group $G$. Results considering the stratification, foliation and fibration of the phase space and the orbit space are considered. Finally some remarks are made concerning relative equilibria and bifurcations of periodic solutions. We will combine results from a wide variety of papers. We obtain that for the orbit space the orbit type stratification coincides with the Thom-Boardman stratification and each stratum is foliated with symplectic leaves. Furthermore the orbit space is fibred into reduced phase spaces and each reduced phase space has a orbit type stratification, where each orbit type stratum is a symplectic leaf., Comment: In version 2 there are slight changes in formulation. Examples of SO(3) symmetry are added. 28 pages, 2 figures, 80 references
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- 2023
3. Intravasale infecties en sepsis
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van der Meer, J. T. M., Cartuyvels, R., Wiersinga, W. J., Hoepelman, prof. dr. A.I.M., editor, Kroes, prof. dr. A.C.M., editor, Lagrou, prof. dr. K., editor, Van der Hilst, prof. dr. J.C.H., editor, Wertheim, prof. dr. H.F.L., editor, Bonten, prof. dr. M.J.M., editor, van Hellemond, dr. J.J., editor, Vlieghe, prof. dr. E.R.J., editor, and van Vugt, prof. dr. M., editor
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- 2024
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4. Bridging AI and Clinical Practice: Integrating Automated Sleep Scoring Algorithm with Uncertainty-Guided Physician Review
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Bechny M, Monachino G, Fiorillo L, van der Meer J, Schmidt MH, Bassetti CLA, Tzovara A, and Faraci FD
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automated sleep scoring ,uncertainty quantification ,explainable ai ,polysomnography ,sleep medicine ,Psychiatry ,RC435-571 ,Neurophysiology and neuropsychology ,QP351-495 - Abstract
Michal Bechny,1,2 Giuliana Monachino,1,2 Luigi Fiorillo,2 Julia van der Meer,3 Markus H Schmidt,3,4 Claudio LA Bassetti,3 Athina Tzovara,1,3 Francesca D Faraci2 1Institute of Computer Science, University of Bern, Bern, Switzerland; 2Institute of Digital Technologies for Personalized Healthcare (Meditech), University of Applied Sciences and Arts of Southern Switzerland, Lugano, Switzerland; 3Department of Neurology, University Hospital of Bern, Bern, Switzerland; 4Ohio Sleep Medicine Institute, Dublin, OH, USACorrespondence: Michal Bechny, Institute of Digital Technologies for Personalized Healthcare, East Campus USI-SUPSI, Via la Santa 1, CH-6962 Lugano-Viganello, Lugano, Switzerland, Tel +41 (0)58 666 65 10, Email bechnymichal@gmail.comPurpose: This study aims to enhance the clinical use of automated sleep-scoring algorithms by incorporating an uncertainty estimation approach to efficiently assist clinicians in the manual review of predicted hypnograms, a necessity due to the notable inter-scorer variability inherent in polysomnography (PSG) databases. Our efforts target the extent of review required to achieve predefined agreement levels, examining both in-domain (ID) and out-of-domain (OOD) data, and considering subjects’ diagnoses.Patients and Methods: A total of 19,578 PSGs from 13 open-access databases were used to train U-Sleep, a state-of-the-art sleep-scoring algorithm. We leveraged a comprehensive clinical database of an additional 8832 PSGs, covering a full spectrum of ages (0– 91 years) and sleep-disorders, to refine the U-Sleep, and to evaluate different uncertainty-quantification approaches, including our novel confidence network. The ID data consisted of PSGs scored by over 50 physicians, and the two OOD sets comprised recordings each scored by a unique senior physician.Results: U-Sleep demonstrated robust performance, with Cohen’s kappa (K) at 76.2% on ID and 73.8– 78.8% on OOD data. The confidence network excelled at identifying uncertain predictions, achieving AUROC scores of 85.7% on ID and 82.5– 85.6% on OOD data. Independently of sleep-disorder status, statistical evaluations revealed significant differences in confidence scores between aligning vs discording predictions, and significant correlations of confidence scores with classification performance metrics. To achieve κ ≥ 90% with physician intervention, examining less than 29.0% of uncertain epochs was required, substantially reducing physicians’ workload, and facilitating near-perfect agreement.Conclusion: Inter-scorer variability limits the accuracy of the scoring algorithms to ~80%. By integrating an uncertainty estimation with U-Sleep, we enhance the review of predicted hypnograms, to align with the scoring taste of a responsible physician. Validated across ID and OOD data and various sleep-disorders, our approach offers a strategy to boost automated scoring tools’ usability in clinical settings.Keywords: automated sleep scoring, uncertainty quantification, explainable AI, polysomnography, sleep medicine
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- 2024
5. Good manufacturing practice production of CD34+ progenitor-derived NK cells for adoptive immunotherapy in acute myeloid leukemia
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de Jonge, P. K. J. D., van Hauten, P. M. M., Janssen, L. D., de Goede, A. L., Berrien-Elliott, M. M., van der Meer, J. M. R., Mousset, C. M., Roeven, M. W. H., Foster, M., Blijlevens, N., Hobo, W., Fehniger, T. A., Jansen, J. H., Schaap, N. P. M., and Dolstra, H.
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- 2023
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6. Intravasale infecties en sepsis
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van der Meer, J. T. M., primary, Cartuyvels, R., additional, and Wiersinga, W. J., additional
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- 2023
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7. The interaction of human endothelial cells with chemical gradient surfaces during exposure to flow
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Ruardy, T. G., primary, Moorlag, H. E., additional, Schakenraad, J. M., additional, Van Der Meer, J., additional, Van Der Mei, H. C., additional, and Busscher, H. J., additional
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- 2023
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8. Trends in mortality in people with HIV from 1999 to 2020: a multi-cohort collaboration
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Tusch, E, Ryom, L, Pelchen-Matthews, A, Mocroft, A, Elbirt, D, Oprea, C, Günthard, H, Staehelin, C, Zangerle, R, Suarez, I, Vehreschild, J, Wit, F, Menozzi, M, d'Arminio Monforte, A, Spagnuolo, V, Pradier, C, Carlander, C, Suanzes, P, Wasmuth, J, Carr, A, Petoumenos, K, Borgans, F, Bonnet, F, De Wit, S, El-Sadr, W, Neesgaard, B, Jaschinski, N, Greenberg, L, Hosein, S, Gallant, J, Vannappagari, V, Young, L, Sabin, C, Lundgren, J, Peters, L, Reekie, J, Calvo, G, Dabis, F, Kirk, O, Law, M, Monforte, A, Morfeldt, L, Reiss, P, Weber, R, Lind-Thomsen, A, Brandt, R, Hillebreght, M, Zaheri, S, Scherrer, A, Schöni-Affolter, F, Rickenbach, M, Tavelli, A, Fanti, I, Leleux, O, Mourali, J, Marec, F, Boerg, E, Thulin, E, Sundström, A, Bartsch, G, Thompsen, G, Necsoi, C, Delforge, M, Fontas, E, Caissotti, C, Dollet, K, Mateu, S, Torres, F, Blance, A, Huang, R, Puhr, R, Laut, K, Kristensen, D, Phillips, A, Kamara, D, Smith, C, Hatleberg, C, Raben, D, Matthews, C, Bojesen, A, Grevsen, A, Powderly, B, Shortman, N, Moecklinghoff, C, Reilly, G, Franquet, X, Smit, C, Ross, M, Fux, C, Morlat, P, Friis-Møller, N, Kowalska, J, Bohlius, J, Bower, M, Fätkenheuer, G, Grulich, A, Sjøl, A, Meidahl, P, Iversen, J, Reiss, C, Hillebregt, M, Prins, J, Kuijpers, T, Scherpbier, H, van der Meer, J, Godfried, M, van der Poll, T, Nellen, F, Geerlings, S, van Vugt, M, Pajkrt, D, Bos, J, Wiersinga, W, van der Valk, M, Goorhuis, A, Hovius, J, van Eden, J, Henderiks, A, van Hes, A, Mutschelknauss, M, Nobel, H, Pijnappel, F, Jurriaans, S, Back, N, Zaaijer, H, Berkhout, B, Cornelissen, M, Schinkel, C, Thomas, X, Ziekenhuis, A, van den Berge, M, Stegeman, A, Baas, S, de Looff, L, Versteeg, D, Ziekenhuis, C, Pronk, M, Ammerlaan, H, De Munnik, E, Jansz, A, Tjhie, J, Wegdam, M, Deiman, B, Scharnhorst, V, van der Plas, A, Weijsenfeld, A, van der Ende, M, De Vries-Sluijs, T, van Gorp, E, Schurink, C, Nouwen, J, Verbon, A, Rijnders, B, Bax, H, van der Feltz, M, Bassant, N, van Beek, J, Vriesde, M, van Zonneveld, L, de Oude-Lubbers, A, van den Berg-Cameron, H, Bruinsma-Broekman, F, de Groot, J, de Man, M, Boucher, C, Koopmans, M, van Kampen, J, Pas, S, Mc–sophia, E, Driessen, G, van Rossum, A, van der Knaap, L, Visser, E, Branger, J, Rijkeboer-Mes, A, de Ven, C, Ziekenhuis, H, Schippers, E, van Nieuwkoop, C, van IJperen, J, Geilings, J, van der Hut, G, Franck, P, van Eeden, A, Brokking, W, Groot, M, Elsenburg, L, Damen, M, Kwa, I, Groeneveld, P, Bouwhuis, J, van den Berg, J, van Hulzen, A, van der Bliek, G, Bor, P, Bloembergen, P, Wolfhagen, M, Ruijs, G, Kroon, F, de Boer, M, Bauer, M, Jolink, H, Vollaard, A, Dorama, W, van Holten, N, Claas, E, Wessels, E, den Hollander, J, Pogany, K, Roukens, A, Kastelijns, M, Smit, J, Smit, E, Struik-Kalkman, D, Tearno, C, Bezemer, M, van Niekerk, T, Pontesilli, O, Lowe, S, Lashof, A, Posthouwer, D, Ackens, R, Schippers, J, Vergoossen, R, Weijenberg-Maes, B, van Loo, I, Havenith, T, Leyten, E, Gelinck, L, van Hartingsveld, A, Meerkerk, C, Wildenbeest, G, Mutsaers, J, Jansen, C, Mulder, J, Vrouenraets, S, Lauw, F, van Broekhuizen, M, Paap, H, Vlasblom, D, Smits, P, Zuiderzee, M, Weijer, S, El Moussaoui, R, Bosma, A, van Vonderen, M, van Houte, D, Kampschreur, L, Dijkstra, K, Faber, S, Weel, J, Kootstra, G, Delsing, C, van der Burg-van de Plas, M, Heins, H, Lucas, E, Kortmann, W, van Twillert, G, Stuart, J, Diederen, B, Pronk, D, van Truijen-Oud, F, van der Reijden, W, Jansen, R, Brinkman, K, van den Berk, G, Blok, W, Frissen, P, Lettinga, K, Schouten, W, Veenstra, J, Brouwer, C, Geerders, G, Hoeksema, K, Kleene, M, van der Meché, I, Spelbrink, M, Sulman, H, Toonen, A, Wijnands, S, Kwa, D, Witte, E, Koopmans, P, Keuter, M, van der Ven, A, ter Hofstede, H, Dofferhoff, A, van Crevel, R, Albers, M, Bosch, M, Grintjes-Huisman, K, Zomer, B, Stelma, F, Rahamat-Langendoen, J, Burger, D, Richter, C, Gisolf, E, Hassing, R, ter Beest, G, van Bentum, P, Langebeek, N, Tiemessen, R, Swanink, C, van Lelyveld, S, Soetekouw, R, Hulshoff, N, van der Prijt, L, van der Swaluw, J, Bermon, N, Herpers, B, Veenendaal, D, Verhagen, D, van Wijk, M, Ziekenhuis, S, van Kasteren, M, Brouwer, A, de Wiel, B, Kuipers, M, Santegoets, R, van der Ven, B, Marcelis, J, Buiting, A, Kabel, P, Bierman, W, Scholvinck, H, Wilting, K, Stienstra, Y, Jonge, H, van der Meulen, P, de Weerd, D, Ludwig-Roukema, J, Niesters, H, Riezebos-Brilman, A, van Leer-Buter, C, Knoester, M, Hoepelman, A, Mudrikova, T, Ellerbroek, P, Oosterheert, J, Arends, J, Barth, R, Wassenberg, M, Schadd, E, van Elst-Laurijssen, D, van Oers-Hazelzet, E, Vervoort, S, van Berkel, M, Schuurman, R, Verduyn-Lunel, F, Wensing, A, Peters, E, van Agtmael, M, Bomers, M, de Vocht, J, Heitmuller, M, Laan, L, Pettersson, A, Vandenbroucke-Grauls, C, Ang, C, Kinderziekenhuis, W, Geelen, S, Wolfs, T, Bont, L, Nauta, N, Bezemer, D, van Sighem, A, Boender, T, de Jong, A, Bergsma, D, Hoekstra, P, de Lang, A, Grivell, S, Jansen, A, Rademaker, M, Raethke, M, Meijering, R, Schnörr, S, de Groot, L, van den Akker, M, Bakker, Y, Claessen, E, El Berkaoui, A, Koops, J, Kruijne, E, Lodewijk, C, Munjishvili, L, Peeck, B, Ree, C, Regtop, R, Ruijs, Y, Rutkens, T, van de Sande, L, Schoorl, M, Timmerman, A, Tuijn, E, Veenenberg, L, van der Vliet, S, Wisse, A, Woudstra, T, Tuk, B, Dupon, M, Gaborieau, V, Lacoste, D, Malvy, D, Mercié, P, Neau, D, Pellegrin, J, Tchamgoué, S, Lazaro, E, Cazanave, C, Vandenhende, M, Vareil, M, Gérard, Y, Blanco, P, Bouchet, S, Breilh, D, Fleury, H, Pellegrin, I, Chêne, G, Thiébaut, R, Wittkop, L, Lawson-Ayayi, S, Gimbert, A, Desjardin, S, Lacaze-Buzy, L, Petrov-Sanchez, V, André, K, Bernard, N, Caubet, O, Caunegre, L, Chossat, I, Courtault, C, Dauchy, F, De Witte, S, Dondia, D, Duffau, P, Dutronc, H, Farbos, S, Faure, I, Ferrand, H, Gerard, Y, Greib, C, Hessamfar, M, Imbert, Y, Lataste, P, Marie, J, Mechain, M, Monlun, E, Ochoa, A, Pistone, T, Raymond, I, Receveur, M, Rispal, P, Sorin, L, Valette, C, Viallard, J, Wille, H, Wirth, G, Lafon, M, Trimoulet, P, Bellecave, P, Tumiotto, C, Haramburu, F, Miremeont-Salamé, G, Blaizeau, M, Decoin, M, Hannapier, C, Lenaud, E, Pougetoux, A, Delveaux, S, D’Ivernois, C, Diarra, F, Uwamaliya-Nziyumvira, B, Palmer, G, Conte, V, Sapparrart, V, Law, C, Moore, R, Edwards, S, Hoy, J, Watson, K, Roth, N, Lau, H, Bloch, M, Baker, D, Cooper, D, O’Sullivan, M, Nolan, D, Guelfi, G, Calvo, C, Domingo, P, Sambeat, M, Gatell, J, Del Cacho, E, Cadafalch, J, Fuster, M, Codina, C, Sirera, G, Vaqué, A, Clumeck, N, Gennotte, A, Gerard, M, Kabeya, K, Konopnicki, D, Libois, A, Martin, C, Payen, M, Semaille, P, Van Laethem, Y, Neaton, C, Krum, E, Thompson, G, Wentworth, D, Luskin-Hawk, R, Telzak, E, Abrams, D, Cohn, D, Markowitz, N, Arduino, R, Mushatt, D, Friedland, G, Perez, G, Tedaldi, E, Fisher, E, Gordin, F, Crane, L, Sampson, J, Baxter, J, Gazzard, B, Horban, A, Karpov, I, Losso, M, Pedersen, C, Ristola, M, Rockstroh, J, Fischer, A, Larsen, J, Podlekareva, D, Cozzi-Lepri, A, Shepherd, L, Schultze, A, Amele, S, Kundro, M, Schmied, B, Wien, P, Vassilenko, A, Mitsura, V, Paduto, D, Florence, E, Vandekerckhove, L, Hadziosmanovic, V, Begovac, J, Machala, L, Jilich, D, Sedlacek, D, Kronborg, G, Benfield, T, Gerstoft, J, Katzenstein, T, Møller, N, Ostergaard, L, Wiese, L, Nielsen, L, Zilmer, K, Smidt, J, Siseklinik, N, Aho, I, Viard, J, Duvivier, C, Schmidt, R, Degen, O, Stellbrink, H, Stefan, C, Goethe, J, Bogner, J, Chkhartishvili, N, Gargalianos, P, Xylomenos, G, Armenis, K, Sambatakou, H, Szlávik, J, Gottfredsson, M, Mulcahy, F, Yust, I, Turner, D, Burke, M, Shahar, E, Hassoun, G, Elinav, H, Haouzi, M, Sthoeger, Z, Esposito, R, Mazeu, I, Mussini, C, Mazzotta, F, Gabbuti, A, Annunziata, O, Vullo, V, Lichtner, M, Zaccarelli, M, Antinori, A, Acinapura, R, Plazzi, M, Lazzarin, A, Castagna, A, Gianotti, N, Galli, M, Ridolfo, A, Rozentale, B, Uzdaviniene, V, Matulionyte, R, Staub, T, Hemmer, R, Ormaasen, V, Maeland, A, Bruun, J, Knysz, B, Gasiorowski, J, Inglot, M, Bakowska, E, Flisiak, R, Grzeszczuk, A, Parczewski, M, Maciejewska, K, Aksak-Was, B, Beniowski, M, Mularska, E, Smiatacz, T, Gensing, M, Jablonowska, E, Malolepsza, E, Wojcik, K, Mozer-Lisewska, I, Caldeira, L, Mansinho, K, Maltez, F, Radoi, R, Panteleev, A, Panteleev, O, Yakovlev, A, Trofimora, T, Khromova, I, Kuzovatova, E, Blokhina, I, Novogrod, N, Borodulina, E, Vdoushkina, E, Jevtovic, D, Tomazic, J, Miró, J, Moreno, S, Rodriguez, J, Clotet, B, Jou, A, Paredes, R, Tural, C, Puig, J, Bravo, I, Gutierrez, M, Mateo, G, Laporte, J, Sonnerborg, A, Brännström, I, Flamholc, L, Cavassini, M, Calmy, A, Furrer, H, Battegay, M, Schmid, P, Kuznetsova, A, Kyselyova, G, Sluzhynska, M, Johnson, A, Simons, E, Johnson, M, Orkin, C, Weber, J, Scullard, G, Clarke, A, Leen, C, Morfeldt, C, Thulin, G, Åkerlund, B, Koppel, K, Karlsson, A, Håkangård, C, Castelli, F, Cauda, R, Perri, G, Iardino, R, Ippolito, G, Marchetti, G, Perno, C, von Schloesser, F, Viale, P, Ceccherini-Silberstein, F, Girardi, E, Caputo, S, Puoti, M, Andreoni, M, Ammassari, A, Balotta, C, Bandera, A, Bonfanti, P, Bonora, S, Borderi, M, Calcagno, A, Calza, L, Capobianchi, M, Cingolani, A, Cinque, P, De Luca, A, Biagio, A, Gori, A, Guaraldi, G, Lapadula, G, Madeddu, G, Maggiolo, F, Marcotullio, S, Monno, L, Nozza, S, Roldan, E, Rossotti, R, Rusconi, S, Santoro, M, Saracino, A, Galli, L, Lorenzini, P, Rodano, A, Shanyinde, M, Carletti, F, Carrara, S, Caro, A, Graziano, S, Petrone, F, Prota, G, Quartu, S, Truffa, S, Giacometti, A, Costantini, A, Barocci, V, Angarano, G, Santoro, C, Suardi, C, Donati, V, Verucchi, G, Minardi, C, Quirino, T, Abeli, C, Manconi, P, Piano, P, Cacopardo, B, Celesia, B, Vecchiet, J, Falasca, K, Pan, A, Lorenzotti, S, Sighinolfi, L, Segala, D, Vichi, F, Cassola, G, Viscoli, C, Alessandrini, A, Bobbio, N, Mazzarello, G, Mastroianni, C, Belvisi, V, Caramma, I, Chiodera, A, Milini, P, Rizzardini, G, Moioli, M, Piolini, R, Salpietro, S, Tincati, C, Puzzolante, C, Abrescia, N, Chirianni, A, Borgia, G, Orlando, R, Bonadies, G, Martino, F, Gentile, I, Maddaloni, L, Cattelan, A, Marinello, S, Cascio, A, Colomba, C, Baldelli, F, Schiaroli, E, Parruti, G, Sozio, F, Magnani, G, Ursitti, M, Cristaudo, A, Baldin, G, Capozzi, M, Cicalini, S, Sulekova, L, Iaiani, G, Latini, A, Mastrorosa, I, Savinelli, S, Vergori, A, Cecchetto, M, Viviani, F, Bagella, P, Rossetti, B, Franco, A, Del Vecchio, R, Francisci, D, Giuli, C, Caramello, P, Orofino, G, Sciandra, M, Bassetti, M, Londero, A, Pellizzer, G, Manfrin, V, Starnini, G, Ialungo, A, Central, C, Dellamonica, P, Bernard, E, Courjon, J, Cua, E, De Salvador-Guillouet, F, Durant, J, Etienne, C, Ferrando, S, Mondain-Miton, V, Naqvi, A, Perbost, I, Pillet, S, Prouvost-Keller, B, Pugliese, P, Rio, V, Risso, K, Roger, P, Aubert, V, Bernasconi, E, Böni, J, Braun, D, Bucher, H, Ciuffi, A, Dollenmaier, G, Egger, M, Elzi, L, Fehr, J, Fellay, J, Haerry, D, Hasse, B, Hirsch, H, Hoffmann, M, Hösli, I, Kahlert, C, Kaiser, L, Keiser, O, Klimkait, T, Kouyos, R, Kovari, H, Ledergerber, B, Martinetti, G, de Tejada, B, Marzolini, C, Metzner, K, Müller, N, Nicca, D, Pantaleo, G, Paioni, P, Rauch, A, Rudin, C, Speck, R, Stöckle, M, Tarr, P, Trkola, A, Vernazza, P, Wandeler, G, Yerly, S, Valk, M, Hutchinson, J, Rupasinghe, D, Han, W, Appoyer, H, Vera, J, Broster, B, Barbour, L, Carney, D, Greenland, L, Coughlan, R, Saint-Pierre, C, Stephan, C, Bucht, M, Chokoshvili, O, Borghi, V, Casabona, J, Miro, J, Lampe, F, Burns, F, Chaloner, C, Muccini, C, Lolatto, R, Sönnerborg, A, Nowak, P, Vesterbacka, J, Mattsson, L, Carrick, D, Stigsäter, K, Kusejko, K, Schulze, N, Franke, B, Rooney, J, Mcnicholl, I, Garges, H, Campo, R, Volny-Anne, A, Dedes, N, Williams, E, Bruguera, A, Volny-Anne, R, Mendão, L, Timiryasova, A, Fursa, O, Jakobsen, M, Kraef, C, Gardizi, M, Andersen, K, Kumar, L, Elsing, T, Shahi, S, Valdenmaiier, O, Bansi-Matharu, L, Byonanebye, D, Bannister, W, Roen, A, Null, N, Tusch, Erich, Ryom, Lene, Pelchen-Matthews, Annegret, Mocroft, Amanda, Elbirt, Daniel, Oprea, Cristiana, Günthard, Huldrych F, Staehelin, Cornelia, Zangerle, Robert, Suarez, Isabelle, Vehreschild, Jörg Janne, Wit, Ferdinand, Menozzi, Marianna, d'Arminio Monforte, Antonella, Spagnuolo, Vincenzo, Pradier, Christian, Carlander, Christina, Suanzes, Paula, Wasmuth, Jan-Christian, Carr, Andrew, Petoumenos, Kathy, Borgans, Frauke, Bonnet, Fabrice, De Wit, Stephane, El-Sadr, Wafaa, Neesgaard, Bastian, Jaschinski, Nadine, Greenberg, Lauren, Hosein, Sean R, Gallant, Joel, Vannappagari, Vani, Young, Lital, Sabin, Caroline, Lundgren, Jens, Peters, Lars, Reekie, Joanne, Monforte, A d’Arminio, Brandt, R Salbøl, Wit, F W N M, Marec, F Le, Laut, K Grønborg, Sabin, C A, Phillips, A N, Kamara, D A, Smith, C J, Hatleberg, C I, Brandt, R S, Grevsen, A L, Lundgren, J D, Fux, C A, Monforte, A d'Arminio, Iversen, J S, Reiss, Central P, Prins, J M, Kuijpers, T W, Scherpbier, H J, van der Meer, J T M, Godfried, M H, Nellen, F J B, Geerlings, S E, Bos, J C, Wiersinga, W J, Hovius, J W, van Hes, A M H, 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P, Rauch, A, Rudin, C, Speck, R, Stöckle, M, Tarr, P, Trkola, A, Vernazza, P, Wandeler, G, Yerly, S, Valk, M, Hutchinson, J, Rupasinghe, D, Han, W, Appoyer, H, Vera, J, Broster, B, Barbour, L, Carney, D, Greenland, L, Coughlan, R, Saint-Pierre, C, Stephan, C, Bucht, M, Chokoshvili, O, Borghi, V, Casabona, J, Miro, J, Lampe, F, Burns, F, Chaloner, C, Muccini, C, Lolatto, R, Sönnerborg, A, Nowak, P, Vesterbacka, J, Mattsson, L, Carrick, D, Stigsäter, K, Kusejko, K, Schulze, N, Franke, B, Rooney, J, Mcnicholl, I, Garges, H, Campo, R, Volny-Anne, A, Dedes, N, Williams, E, Bruguera, A, Volny-Anne, R, Mendão, L, Timiryasova, A, Fursa, O, Jakobsen, M, Kraef, C, Gardizi, M, Andersen, K, Kumar, L, Elsing, T, Shahi, S, Valdenmaiier, O, Bansi-Matharu, L, Byonanebye, D, Bannister, W, Roen, A, Null, N, Tusch, Erich, Ryom, Lene, Pelchen-Matthews, Annegret, Mocroft, Amanda, Elbirt, Daniel, Oprea, Cristiana, Günthard, Huldrych F, Staehelin, Cornelia, Zangerle, Robert, Suarez, Isabelle, Vehreschild, Jörg Janne, Wit, Ferdinand, Menozzi, Marianna, d'Arminio Monforte, Antonella, Spagnuolo, Vincenzo, Pradier, Christian, Carlander, Christina, Suanzes, Paula, Wasmuth, Jan-Christian, Carr, Andrew, Petoumenos, Kathy, Borgans, Frauke, Bonnet, Fabrice, De Wit, Stephane, El-Sadr, Wafaa, Neesgaard, Bastian, Jaschinski, Nadine, Greenberg, Lauren, Hosein, Sean R, Gallant, Joel, Vannappagari, Vani, Young, Lital, Sabin, Caroline, Lundgren, Jens, Peters, Lars, Reekie, Joanne, Monforte, A d’Arminio, Brandt, R Salbøl, Wit, F W N M, Marec, F Le, Laut, K Grønborg, Sabin, C A, Phillips, A N, Kamara, D A, Smith, C J, Hatleberg, C I, Brandt, R S, Grevsen, A L, Lundgren, J D, Fux, C A, Monforte, A d'Arminio, Iversen, J S, Reiss, Central P, Prins, J M, Kuijpers, T W, Scherpbier, H J, van der Meer, J T M, Godfried, M H, Nellen, F J B, Geerlings, S E, Bos, J C, Wiersinga, W J, Hovius, J W, van Hes, A M H, Nobel, H E, Pijnappel, F J J, Back, N K T, Zaaijer, H L, Cornelissen, M T E, Schinkel, C J, Thomas, X V, Ziekenhuis, Admiraal De Ruyter, de Looff, L Hage, Ziekenhuis, Catharina, Pronk, M J H, Ammerlaan, H S M, De Munnik, E S, Jansz, A R, Wegdam, M C A, Weijsenfeld, A M, van der Ende, M E, De Vries-Sluijs, T E M S, van Gorp, E C M, Schurink, C A M, Nouwen, J L, Rijnders, B J A, Bax, H I, van Beek, J E A, van Zonneveld, L M, van den Berg-Cameron, H J, Bruinsma-Broekman, F B, de Man, M de Zeeuw, Boucher, C A B, Koopmans, M P G, van Kampen, J J A, Pas, S D, MC–Sophia, Erasmus, Driessen, G J A, van Rossum, A M C, van der Knaap, L C, de Ven, C J H M Duijf-van, Ziekenhuis, Haga, Schippers, E F, van IJperen, J M, Franck, P F H, Elsenburg, L J M, Kwa, I S, Groeneveld, P H P, Bouwhuis, J W, van den Berg, J F, van Hulzen, A G W, van der Bliek, G L, Bor, P C J, Wolfhagen, M J H M, Ruijs, G J H M, Kroon, F P, de Boer, M G J, Bauer, M P, Vollaard, A M, Claas, E C J, den Hollander, J G, Smit, J V, Lowe, S H, Lashof, A M L Oude, Ackens, R P, van Loo, I H M, Havenith, T R A, Leyten, E M S, Gelinck, L B S, Wildenbeest, G S, Mutsaers, J A E M, Jansen, C L, Mulder, J W, Vrouenraets, S M E, Lauw, F N, van Broekhuizen, M C, Vlasblom, D J, Smits, P H M, Zuiderzee, M C, Bosma, A S, van Vonderen, M G A, van Houte, D P F, Kampschreur, L M, Kootstra, G J, Delsing, C E, Stuart, J W T Cohen, Diederen, B M W, van Truijen-Oud, F A, van der Reijden, W A, van den Berk, G E L, Blok, W L, Frissen, P H J, Lettinga, K D, Schouten, W E M, Brouwer, C J, Geerders, G F, Kleene, M J, van der Meché, I B, Toonen, A J M, Koopmans, P P, van der Ven, A J A M, ter Hofstede, H J M, Dofferhoff, A S M, Bosch, M E W, Grintjes-Huisman, K J T, Zomer, B J, Stelma, F F, Gisolf, E H, Hassing, R J, van Bentum, P H M, Swanink, C M A, van Lelyveld, S F L, van der Prijt, L M M, Herpers, B L, Verhagen, D W M, Ziekenhuis, St Elisabeth, van Kasteren, M E E, Brouwer, A E, de Wiel, B A F M de Kruijf-van, Santegoets, R M W J, Marcelis, J H, Buiting, A G M, Kabel, P J, Bierman, W F W, Wilting, K R, Jonge, H de Groot-de, van der Meulen, P A, de Weerd, D A, Niesters, H G M, van Leer-Buter, C C, Hoepelman, A I M, Ellerbroek, P M, Oosterheert, J J, Arends, J E, Barth, R E, Wassenberg, M W M, Schadd, E M, van Elst-Laurijssen, D H M, van Oers-Hazelzet, E E B, Wensing, A M J, Peters, E J G, van Agtmael, M A, Laan, L M, Pettersson, A M, Vandenbroucke-Grauls, C M J E, Ang, C W, Kinderziekenhuis, Wilhelmina, Geelen, S P M, Wolfs, T F W, Bont, L J, Bezemer, D O, van Sighem, A I, Boender, T S, Rademaker, M J, Pellegrin, J L, Vareil, M O, Dauchy, F A, Receveur, M C, Vandenhende, M A, Viallard, J F, Lafon, Me, Blaizeau, M J, Boerg, Eloïse, Law, Central M, Calvo, Central G, Sambeat, M A, Gennotte, A F, Payen, M C, Neaton, Central J, El-Sadr, W M, Abrams, D I, Crane, L R, Fischer, A H, Larsen, J F, Wien, Pulmologisches Zentrum der Stadt, Mitsura, V M, Møller, N F, Nielsen, L N, Smidt, Jelena, Siseklinik, Nakkusosakond, Viard, J-P, Stellbrink, H J, Goethe, J W, Sthoeger, Z M, Monforte, A D’Arminio, Annunziata, Ospedale S Maria, Blokhina, I N, Novogrod, Nizhny, Gatell, J M, Miró, J M, Rodriguez, J M, Laporte, J M, Johnson, A M, Johnson, M A, Morfeldt, Central L, Perri, G Di, Marchetti, G C, Perno, C F, Caputo, S Lo, Capobianchi, M R, Biagio, A Di, Roldan, E Quiros, Santoro, M M, Caro, A Di, Manconi, P E, Moioli, M C, Ridolfo, A L, Martino, F Di, Cattelan, A M, Ursitti, M A, Sulekova, L Fontanelli, Plazzi, M M, Del Vecchio, R Fontana, Giuli, C Di, Orofino, G C, Roger, P M, Braun, D L, Bucher, H C, Günthard, H F, Hirsch, H H, Kouyos, R D, de Tejada, B Martinez, Metzner, K J, Scherrer, A U, Valk, Marc vd, Han, W Min, Saint-Pierre, C H U, Miro, J M, Wasmuth, J C, Vehreschild, J J, McNicholl, I, Williams, E D, Volny-Anne, R Campo Alain, Dedes, Nikos, Mendão, Luis, Jakobsen, M L, Kumar, L Ramesh, Elsing, T W, and null, null
- Abstract
Background: Mortality among people with HIV declined with the introduction of combination antiretroviral therapy. We investigated trends over time in all-cause and cause-specific mortality in people with HIV from 1999-2020. Methods: Data were collected from the D:A:D cohort from 1999 through January 2015 and RESPOND from October 2017 through 2020. Age-standardized all-cause and cause-specific mortality rates, classified using Coding Causes of Death in HIV (CoDe), were calculated. Poisson regression models were used to assess mortality trends over time. Results: Among 55716 participants followed for a median of 6 years (IQR 3-11), 5263 participants died (crude mortality rate [MR] 13.7/1000 PYFU; 95%CI 13.4-14.1). Changing patterns of mortality were observed with AIDS as the most common cause of death between 1999- 2009 (n = 952, MR 4.2/1000 PYFU; 95%CI 4.0-4.5) and non-AIDS defining malignancy (NADM) from 2010 -2020 (n = 444, MR 2.8/1000 PYFU; 95%CI 2.5-3.1). In multivariable analysis, all-cause mortality declined over time (adjusted mortality rate ratio [aMRR] 0.97 per year; 95%CI 0.96, 0.98), mostly from 1999 through 2010 (aMRR 0.96 per year; 95%CI 0.95-0.97), and with no decline shown from 2011 through 2020 (aMRR 1·00 per year; 95%CI 0·96-1·05). Mortality due all known causes except NADM also declined over the entire follow-up period. Conclusion: Mortality among people with HIV in the D:A:D and/or RESPOND cohorts decreased between 1999 and 2009 and was stable over the period from 2010 through 2020. The decline in mortality rates was not fully explained by improvements in immunologic-virologic status or other risk factors.
- Published
- 2024
9. IL-15 superagonist N-803 improves IFNγ production and killing of leukemia and ovarian cancer cells by CD34+ progenitor-derived NK cells
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Van der Meer, J. M. R., Maas, R. J. A., Guldevall, K., Klarenaar, K., de Jonge, P. K. J. D., Evert, J. S. Hoogstad-van, van der Waart, A. B., Cany, J., Safrit, J. T., Lee, J. H., Wagena, E., Friedl, P., Önfelt, B., Massuger, L. F., Schaap, N. P. M., Jansen, J. H., Hobo, W., and Dolstra, H.
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- 2021
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10. Genitaliën en rectum
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van der Meer, J., van der Meer, J.W.M., editor, Postma, C.T., editor, Blockmans, D.E., editor, and de Rooij, S.E.J.A., editor
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- 2019
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11. Quantifying dynamics of sleep in subjects with sleep-disordered breathing: towards new biomarkers
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Bechny, M., primary, Fiorillo, L., additional, Monachino, G., additional, van der Meer, J., additional, Schmidt, M.H., additional, Bassetti, C.L.A., additional, Tzovara, A., additional, and Faraci, F.D., additional
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- 2024
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12. Do state-of-the-art sleep-scoring algorithms preserve clinical information?
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Bechny, M., primary, Fiorillo, L., additional, Monachino, G., additional, van der Meer, J., additional, Schmidt, M.H., additional, Bassetti, C.L.A., additional, Tzovara, A., additional, and Faraci, F.D., additional
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- 2024
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13. Long-term ambulatory monitoring and identification of digital biomarkers in narcolepsy
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Gnarra, O., primary, van der Meer, J., additional, Warncke, J.D., additional, Fregolente, L.G., additional, Wenz, E., additional, Nwachukwu, U., additional, Khatami, R., additional, von Manitius, S., additional, Miano, S., additional, Acker, J., additional, Strub, M., additional, Riener, R., additional, Bassetti, C.L., additional, and Schmidt, M.H., additional
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- 2024
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14. Correction to: Comparative effectiveness of β-lactams for empirical treatment of methicillin-susceptible Staphylococcus aureus bacteraemia: a prospective cohort study
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Buis, D T P, primary, van der Vaart, T W, additional, Prins, J M, additional, van der Meer, J T M, additional, Bonten, M J M, additional, Sieswerda, E, additional, van Werkhoven, C H, additional, and Sigaloff, K C E, additional
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- 2023
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15. Implementation of the 2015 European Society of Cardiology guidelines for the management of infective endocarditis in the Netherlands
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Wahadat, A. R., Deckers, J. W., Budde, R. P. J., van der Meer, J. T. M., Natour, E. H., ten Oever, J., Kortlever-van der Spek, A. L. J., Stegeman, B. H., Verkaik, N. J., Roos-Hesselink, J. W., and Tanis, W.
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- 2020
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16. De thorax
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van der Meer, J.W.M, van der Meer, J., Linthorst, G., Postma, C.T., Blockmans, D., van der Meer, J.W.M, editor, van der Meer, J., editor, Linthorst, G., editor, Postma, C.T., editor, and Blockmans, D., editor
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- 2016
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17. Methoden van het lichamelijk onderzoek
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van der Meer, J.W.M, van der Meer, J., Linthorst, G., Postma, C.T., Blockmans, D., van der Meer, J.W.M, editor, van der Meer, J., editor, Linthorst, G., editor, Postma, C.T., editor, and Blockmans, D., editor
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- 2016
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18. Het algemeen onderzoek
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van der Meer, J.W.M, van der Meer, J., Linthorst, G., Postma, C.T., Blockmans, D., van der Meer, J.W.M, editor, van der Meer, J., editor, Linthorst, G., editor, Postma, C.T., editor, and Blockmans, D., editor
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- 2016
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19. Hoofd en hals
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van der Meer, J.W.M, van der Meer, J., Linthorst, G., Postma, C.T., Blockmans, D., van der Meer, J.W.M, editor, van der Meer, J., editor, Linthorst, G., editor, Postma, C.T., editor, and Blockmans, D., editor
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- 2016
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20. De algemene anamnese
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van der Meer, J.W.M, van der Meer, J., Linthorst, G., Postma, C.T., Blockmans, D., van der Meer, J.W.M, editor, van der Meer, J., editor, Linthorst, G., editor, Postma, C.T., editor, and Blockmans, D., editor
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- 2016
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21. De anamnese gericht op de hoofdklacht
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van der Meer, J.W.M, van der Meer, J., Linthorst, G., Postma, C.T., Blockmans, D., van der Meer, J.W.M, editor, van der Meer, J., editor, Linthorst, G., editor, Postma, C.T., editor, and Blockmans, D., editor
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- 2016
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22. Veelvoorkomende klachten
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van der Meer, J.W.M, van der Meer, J., Linthorst, G., Postma, C.T., Blockmans, D., van der Meer, J.W.M, editor, van der Meer, J., editor, Linthorst, G., editor, Postma, C.T., editor, and Blockmans, D., editor
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- 2016
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23. Het diagnostisch proces
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van der Meer, J.W.M, van der Meer, J., Linthorst, G., Postma, C.T., Blockmans, D., van der Meer, J.W.M, editor, van der Meer, J., editor, Linthorst, G., editor, Postma, C.T., editor, and Blockmans, D., editor
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- 2016
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24. De anamnese: algemene principes
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van der Meer, J.W.M, van der Meer, J., Linthorst, G., Postma, C.T., Blockmans, D., van der Meer, J.W.M, editor, van der Meer, J., editor, Linthorst, G., editor, Postma, C.T., editor, and Blockmans, D., editor
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- 2016
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25. Het patiëntendossier
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van der Meer, J.W.M, van der Meer, J., Linthorst, G., Postma, C.T., Blockmans, D., van der Meer, J.W.M, editor, van der Meer, J., editor, Linthorst, G., editor, Postma, C.T., editor, and Blockmans, D., editor
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- 2016
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26. De geriatrische patiënt
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van der Meer, J.W.M, van der Meer, J., Linthorst, G., Postma, C.T., Blockmans, D., van der Meer, J.W.M, editor, van der Meer, J., editor, Linthorst, G., editor, Postma, C.T., editor, and Blockmans, D., editor
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- 2016
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27. Het neurologisch onderzoek
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van der Meer, J.W.M, van der Meer, J., Linthorst, G., Postma, C.T., Blockmans, D., van der Meer, J.W.M, editor, van der Meer, J., editor, Linthorst, G., editor, Postma, C.T., editor, and Blockmans, D., editor
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- 2016
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28. De gewrichten
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van der Meer, J.W.M, van der Meer, J., Linthorst, G., Postma, C.T., Blockmans, D., van der Meer, J.W.M, editor, van der Meer, J., editor, Linthorst, G., editor, Postma, C.T., editor, and Blockmans, D., editor
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- 2016
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29. De extremiteiten
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van der Meer, J.W.M, van der Meer, J., Linthorst, G., Postma, C.T., Blockmans, D., van der Meer, J.W.M, editor, van der Meer, J., editor, Linthorst, G., editor, Postma, C.T., editor, and Blockmans, D., editor
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- 2016
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30. Genitaliën en rectum
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van der Meer, J.W.M, van der Meer, J., Linthorst, G., Postma, C.T., Blockmans, D., van der Meer, J.W.M, editor, van der Meer, J., editor, Linthorst, G., editor, Postma, C.T., editor, and Blockmans, D., editor
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- 2016
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31. De buik
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van der Meer, J.W.M, van der Meer, J., Linthorst, G., Postma, C.T., Blockmans, D., van der Meer, J.W.M, editor, van der Meer, J., editor, Linthorst, G., editor, Postma, C.T., editor, and Blockmans, D., editor
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- 2016
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32. Infectie en sepsis
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Dormans, T. P. J., van der Meer, J. W. M., Bruining, H.A., editor, Lauwers, P., editor, and Thijs, L.G., editor
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- 2017
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33. De patiënt-artsrelatie
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van der Meer, J.W.M, van der Meer, J., Linthorst, G., Postma, C.T., Blockmans, D., van der Meer, J.W.M, editor, van der Meer, J., editor, Linthorst, G., editor, Postma, C.T., editor, and Blockmans, D., editor
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- 2016
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34. De samenvatting van het onderzoek
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van der Meer, J.W.M, van der Meer, J., Linthorst, G., Postma, C.T., Blockmans, D., van der Meer, J.W.M, editor, van der Meer, J., editor, Linthorst, G., editor, Postma, C.T., editor, and Blockmans, D., editor
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- 2016
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35. Long-term changes in annual growth of bivalves in the Wadden Sea : influences of temperature, food, and abundance
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Beukema, J. J., Dekker, R., Drent, J., and van der Meer, J.
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- 2017
36. Microbial Composition and Structure of a Rotating Biological Contactor Biofilm Treating Ammonium-Rich Wastewater without Organic Carbon
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Zehnder, A. J. B. and van der Meer, J. R.
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- 2003
37. Intravasale infecties en sepsis
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van der Meer, J. T. M., Nouwen, J. L., Wiersinga, W. J., Hoepelman, A. I. M., editor, Kroes, A. C. M., editor, Sauerwein, R. W., editor, Verbrugh, H. A., editor, and Nouwen, J. L., editor
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- 2016
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38. Infecties bij patiënten met een gestoorde afweer
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van der Meer, J. W. M., Verweij, P. E., Niesters, H. G. M., van Leer-Buter, C. C., Hoepelman, A. I. M., editor, Kroes, A. C. M., editor, Sauerwein, R. W., editor, Verbrugh, H. A., editor, and Nouwen, J. L., editor
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- 2016
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39. Verworven stoornissen van de afweer
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van der Meer, J. W. M., Savelkoul, H., Rijkers, G.T., editor, Kroese, F.G.M., editor, Kallenberg, C.G.M., editor, and Derksen, R.H.W.M., editor
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- 2016
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40. Antimicrobiële therapie
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van der Meer, J. W. M., Bruining, H.A., editor, Lauwers, P., editor, and Thijs, L.G., editor
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- 2017
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41. Predicting Shorebird Mortality and Population Size under Different Regimes of Shellfishery Management
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Stillman, R. A., Goss-Custard, J. D., West, A. D., McGrorty, S., Caldow, R. W. G., Norris, K. J., Johnstone, I. G., Ens, B. J., Van Der Meer, J., and Triplet, P.
- Published
- 2001
42. Erratum bij: Anamnese en lichamelijk onderzoek
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van der Meer, J. W. M., primary, Postma, C. T., additional, Blockmans, D. E., additional, and de Rooij, S. E. J. A., additional
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- 2019
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43. An Objection to the Scarlatti Chronology of Van der Meer
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Sloane, Carl and van der Meer, J. H.
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- 2000
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- View/download PDF
44. Correction to: IL‑15 superagonist N‑803 improves IFNγ production and killing of leukemia and ovarian cancer cells by CD34+ progenitor‑derived NK cells
- Author
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Van der Meer, J. M. R., Maas, R. J. A., Guldevall, K., Klarenaar, K., De Jonge, P. K. J. D., Hoogstad-van Evert, J. S., van der Waart, A. B., Cany, J., Safrit, J. T., Lee, J. H., Wagena, E., Friedl, P., Önfelt, B., Massuger, L. F., Schaap, N. P. M., Jansen, J. H., Hobo, W., and Dolstra, H.
- Published
- 2021
- Full Text
- View/download PDF
45. Maintenance of Light-Standards-A Case-Study
- Author
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Dekker, R., van der Meer, J. R., Wildeman, R. E., and de Bruin, J. J.
- Published
- 1998
- Full Text
- View/download PDF
46. Comparative effectiveness of β-lactams for empirical treatment of methicillin-susceptible Staphylococcus aureus bacteraemia: a prospective cohort study
- Author
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Buis, D T P, primary, van der Vaart, T W, additional, Prins, J M, additional, van der Meer, J T M, additional, Bonten, M J M, additional, Sieswerda, E, additional, van Werkhoven, C H, additional, Sigaloff, K C E, additional, Herpers, B L, additional, Jansen, R R, additional, Rozemeijer, W, additional, Soetekouw, R, additional, van Twillert, G, additional, and Veenstra, J, additional
- Published
- 2023
- Full Text
- View/download PDF
47. The Contribution of Intermediary Factors to Marital Status Differences in Self-Reported Health
- Author
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Joung, I. M. A., Stronks, K., van de Mheen, H., van Poppel, F. W. A., van der Meer, J. B. W., and Mackenbach, J. P.
- Published
- 1997
- Full Text
- View/download PDF
48. Gaan de oceanen de wereld voeden?
- Author
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van der Meer, J. and van der Meer, J.
- Abstract
Hoewel de oppervlakte van de aarde voor meer dan 70% bedekt is door water, komt het leeuwendeel van het menselijke voedsel van land. Maar de tijd is rijp om de zeeën en oceanen nu echt te gaan benutten voor voedselproductie, zo viel de laatste decennia vaak te horen. De optimistische opvattingen over een ‘blauwe revolutie’ zijn onlangs echter aangevochten en met name de toekomstige rol van de mariene viskweek wordt in twijfel getrokken. Belangrijke stappen in het verhogen van de wereldwijde productie van eiwitrijke dierlijke producten uit zee kunnen alleen worden verwacht van aquacultuur van organismen laag uit de voedselketen, zoals schelpdieren. Naast het leveren van gezonde mariene eiwitproducten heeft de schelpdierkweek het voordeel dat het weinig schade toebrengt aan het milieu.
- Published
- 2023
49. Space–time analyses of sediment composition reveals synchronized dynamics at all intertidal flats in the Dutch Wadden Sea
- Author
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Folmer, E.O., Bijleveld, A., Holthuijsen, S., van der Meer, J., Piersma, T., van der Veer, H., Folmer, E.O., Bijleveld, A., Holthuijsen, S., van der Meer, J., Piersma, T., and van der Veer, H.
- Abstract
Intertidal mudflat systems are shaped by geological processes and an interplay of hydrodynamics, sediment availability and ecological processes. All around the world these systems are affected by relative sea level rise (RSLR), changing climate and by human activities such as sediment nourishments, dredging, hydrological engineering and bottom trawling. These kinds of perturbations cause changes in morphology and sediment composition which may cause shifts in the composition, spatial distribution and productivity of benthic communities. We analysed the spatial and temporal variability of the sediment grain size of more than 900 km2 intertidal flats in the Dutch Wadden Sea in the period 2009–2019. The large scale coverage was achieved by yearly grid sampling at more than 4000 stations. Spatial panel data models were used to analyse changes in median grain size and mud content between years and to estimate the effects of resuspension due to wind and the accumulation of silt during summer. We show that between years the sediments of the intertidal flats changed synchronously throughout the study area and that the flats became coarser during the period 2011–2015 and muddier again between 2015 and 2019. The system wide changes and the absence of clear local deviations leads to the hypothesis that a large scale factor like changing hydrodynamic regime (e.g. due to RSLR), variability in the composition of suspended sediment in the North Sea or changing microphytobenthic productivity were causally involved in the coarsening of intertidal flats. Our data and analysis provides a base for further scientific enquiry but longer time series on higher temporal resolution of both sediment data and the physical and ecological environment are required. Models simulating the environment may provide further insight into possible development of sediment composition of the intertidal flats of the Wadden Sea.
- Published
- 2023
50. A re‐evaluation of the effects of mechanical cockle dredging in the Dutch Wadden Sea
- Author
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van der Meer, J., Folmer, Eelke, van der Meer, J., and Folmer, Eelke
- Abstract
1. Marine bivalves provide an important seafood resource, but conflicts between bivalve fisheries and conservation goals may arise.2. A scientific debate about cockle dredging in the Dutch Wadden Sea resulted in an apparent consensus among scientists of a severe and long-lasting impact of the mechanical fisheries, and the fisheries were banned.3. Specifically, two highly cited papers concluded that the fisheries caused a strong reduction in bivalve recruitment for a period of 8 years and that the fisheries led to the loss of red knots from the Dutch Wadden Sea and a decline of the European wintering population.4. Here, we show that these papers had severe shortcomings in terms of data selection and data analysis and we challenge their conclusions.
- Published
- 2023
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