134 results on '"van der Pol, Leo A."'
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2. The TB vaccine development pathway – An innovative approach to accelerating global TB vaccine development
3. Automated cell counting for Trypan blue-stained cell cultures using machine learning
4. Bioengineering bacterial outer membrane vesicles as vaccine platform
5. Platform Technology for Viral Vaccine Production: Comparison Between Attached and Suspension Vero Cells
6. Scale-Down of the Salk Inactivated Polio Vaccine Production Process
7. Development of Inactivated Polio Vaccine (IPV) Derived from Attenuated Sabin Strains
8. Scale-Down Approach for Animal-Free Polio Vaccine Production
9. Improved poliovirus d-antigen yields by application of different Vero cell cultivation methods
10. Comparison of initial feasibility of host cell lines for viral vaccine production
11. Contract Manufacturing of Biopharmaceutical Grade Antibodies
12. Transfer of an adherent Vero cell culture method between two different rocking motion type bioreactors with respect to cell growth and metabolic rates
13. Assessment of mass transfer and mixing in rigid lab-scale disposable bioreactors at low power input levels
14. Expression of phosphofructokinase in Neisseria meningitidis
15. How to choose the correct cell line for producing your viral vaccine: what is important?
16. Scaling-up vaccine production: implementation aspects of a biomass growth observer and controller
17. Online automatic tuning and control for fed-batch cultivation
18. Scale-up for bulk production of vaccine against meningococcal disease
19. PAT for vaccines: The first stage of PAT implementation for development of a well-defined whole-cell vaccine against whooping cough disease
20. Platform Technology for Viral Vaccine Production: Comparison Between Attached and Suspension Vero Cells
21. Scale-Down of the Salk Inactivated Polio Vaccine Production Process
22. Development of Inactivated Polio Vaccine (IPV) Derived from Attenuated Sabin Strains
23. Quality-control issues and approaches in vaccine development
24. Semi-continuous production with the baculovirus expression system
25. EFFECT OF REDUCING THE SERUM OR ALBUMIN CONCENTRATIONS ON THE SHEAR SENSITIVITY OF TWO HYBRIDOMA CELL LINES IN SPARGED CULTURES
26. Proteome Analysis Is a Valuable Tool to Monitor Antigen Expression during Upstream Processing of Whole-Cell Pertussis Vaccines
27. Efficient chromatographic reduction of ovalbumin for egg-based influenza virus purification
28. Influenza Vaccine Manufacturing: Effect of Inactivation, Splitting and Site of Manufacturing. Comparison of Influenza Vaccine Production Processes
29. Outer membrane vesicles as platform vaccine technology
30. Hematopoietic Cancer Cell Lines Can Support Replication of Sabin Poliovirus Type 1
31. Proteome Analysis Is a Valuable Tool to Monitor Antigen Expression during Upstream Processing of Whole-Cell Pertussis Vaccines.
32. Next Generation Inactivated Polio Vaccine Manufacturing to Support Post Polio-Eradication Biosafety Goals
33. Vaccine Development: History, Current Status, and Future Trends
34. Improved Production Process for Native Outer Membrane Vesicle Vaccine against Neisseria meningitidis
35. Isoelectric Point Determination of Live Polioviruses by Capillary Isoelectric Focusing with Whole Column Imaging Detection
36. Quantitative Proteomics Reveals Distinct Differences in the Protein Content of Outer Membrane Vesicle Vaccines
37. Cysteine Depletion Causes Oxidative Stress and Triggers Outer Membrane Vesicle Release by Neisseria meningitidis; Implications for Vaccine Development
38. Scale-down of the inactivated polio vaccine production process
39. Identification and optimization of critical process parameters for the production of NOMV vaccine against Neisseria meningitidis
40. Inactivated polio vaccine development for technology transfer using attenuated Sabin poliovirus strains to shift from Salk-IPV to Sabin-IPV
41. Improved OMV vaccine against Neisseria meningitidis using genetically engineered strains and a detergent-free purification process
42. Multivariate data analysis on historical IPV production data for better process understanding and future improvements
43. Gene-expression-based quality scores indicate optimal harvest point inBordetella pertussiscultivation for vaccine production
44. Evaluation of a critical process parameter: Oxygen limitation during cultivation has a fully reversible effect on gene expression ofBordetella pertussis
45. Scaling-up vaccine production: implementation aspects of a biomass growth observer and controller
46. Online automatic tuning and control for fed-batch cultivation
47. Manufacturing Vaccines: An Illustration of Using PAT Tools for Controlling the Cultivation ofBordetella pertussis
48. Microarrays in vaccine process development: The effect of oxygen limitation on gene expression during batch cultivation of Bordetella pertussis
49. Modeling Neisseria meningitidis metabolism: from genome to metabolic fluxes
50. Shear sensitivity of animal cells from a culture-medium perspective
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