518 results on '"von Kriegsheim, Alex"'
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2. Loss of DOCK2 potentiates Inflammatory Bowel Disease–associated colorectal cancer via immune dysfunction and IFNγ induction of IDO1 expression
3. Role of inflammatory signaling pathways involving the CD40–CD40L–TRAF cascade in diabetes and hypertension—insights from animal and human studies
4. The V-ATPase complex component RNAseK is required for lysosomal hydrolase delivery and autophagosome degradation
5. Involvement of Kindlin-1 in cutaneous squamous cell carcinoma
6. Ciliary tip actin dynamics regulate photoreceptor outer segment integrity
7. Platelet inhibition by hypochlorous acid involves cAMP signalling
8. ALDH1A3-acetaldehyde metabolism potentiates transcriptional heterogeneity in melanoma
9. Carbon, nitrogen, and sulfur elemental and isotopic variations in mouse hair and bone collagen during short-term graded calorie restriction
10. Integrative modeling and analysis of signaling crosstalk reveal molecular switches coordinating Yes-associated protein transcriptional activities
11. Kinome-wide siRNA screen identifies a DCLK2-TBK1 oncogenic signaling axis in clear cell renal cell carcinoma
12. Mena regulates nesprin-2 to control actin–nuclear lamina associations, trans-nuclear membrane signalling and gene expression
13. Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis
14. Histone H3 proline 16 hydroxylation regulates mammalian gene expression
15. Co-exposure to urban particulate matter and aircraft noise adversely impacts the cerebro-pulmonary-cardiovascular axis in mice
16. Recovery of reduced thiol groups by superoxide-mediated denitrosation of nitrosothiols
17. Impaired oxygen-sensitive regulation of mitochondrial biogenesis within the von Hippel–Lindau syndrome
18. MYC sensitises cells to apoptosis by driving energetic demand
19. RNA splicing is a key mediator of tumour cell plasticity and a therapeutic vulnerability in colorectal cancer
20. Characterisation of a nucleo-adhesome
21. Dynamic partitioning of branched-chain amino acids-derived nitrogen supports renal cancer progression
22. ISGylation drives basal breast tumour progression by promoting EGFR recycling and Akt signalling
23. Aircraft noise exposure drives the activation of white blood cells and induces microvascular dysfunction in mice
24. Regional identity of human neural stem cells determines oncogenic responses to histone H3.3 mutants
25. Neutrophils Fuel Effective Immune Responses through Gluconeogenesis and Glycogenesis
26. Asparagine Hydroxylation is a Reversible Post-translational Modification
27. The autophagy protein Ambra1 regulates gene expression by supporting novel transcriptional complexes
28. PRL3-DDX21 Transcriptional Control of Endolysosomal Genes Restricts Melanocyte Stem Cell Differentiation
29. Anti-brain protein autoantibodies are detectable in extraparenchymal but not parenchymal neurocysticercosis
30. EglN3 hydroxylase stabilizes BIM-EL linking VHL type 2C mutations to pheochromocytoma pathogenesis and chemotherapy resistance
31. Role of inflammatory signaling pathways involving the CD40–CD40L–TRAF cascade in diabetes and hypertension—insights from animal and human studies
32. RAC1B modulates intestinal tumourigenesis via modulation of WNT and EGFR signalling pathways
33. Oxygen-sensitive Regulation of Mitochondrial Mass and its implication in the von Hippel-Lindau Syndrome
34. An Integrated Global Analysis of Compartmentalized HRAS Signaling
35. Publisher Correction: Impaired oxygen-sensitive regulation of mitochondrial biogenesis within the von Hippel–Lindau syndrome
36. RASSF1C oncogene elicits amoeboid invasion, cancer stemness, and extracellular vesicle release via a SRC/Rho axis
37. Correction: A novel role of MNT as a negative regulator of REL and the NF-κB pathway
38. Identification of a P62-TIF-IA axis that drives nucleolar fusion and the senescence associated secretory phenotype
39. PHD3 Regulates p53 Protein Stability by Hydroxylating Proline 359
40. ALIX Regulates Tumor-Mediated Immunosuppression by Controlling EGFR Activity and PD-L1 Presentation
41. CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis
42. Potential mechanisms of calcium dependent regulation of the mammalian cell cycle revealed by comprehensive unbiased label-free nLC-MS/MS quantitative proteomics
43. Author Correction: Cell fate decisions are specified by the dynamic ERK interactome
44. SCD inhibition eradicates AML displaying high de novo fatty acid desaturation and synergizes with chemotherapy
45. A novel role of MNT as a negative regulator of REL and the NF-κB pathway
46. Phosphorylation of iRhom2 Controls Stimulated Proteolytic Shedding by the Metalloprotease ADAM17/TACE
47. PLAA Mutations Cause a Lethal Infantile Epileptic Encephalopathy by Disrupting Ubiquitin-Mediated Endolysosomal Degradation of Synaptic Proteins
48. Selective Hypoxia-Sensitive Oxomer Formation by FIH Prevents Binding of the NF-κB Inhibitor IκBβ to NF-κB Subunits.
49. BRD4 interacts with NIPBL and BRD4 is mutated in a Cornelia de Lange–like syndrome
50. RhoGAP6 interacts with COPI to regulate protein transport
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