Back to Search
Start Over
Evaluation of the Toxicity of Pradosia huberi Extract during the Preimplantation in Wistar Rats.
- Source :
-
BioMed Research International . 2013, Vol. 2013, p1-6. 6p. - Publication Year :
- 2013
-
Abstract
- The treatment during the embryonic preimplantation phase of Wistar rats with the Pradosia huberi extract did not interfere with the water and feed consumption, as well as upon the body-weight gain. However, it has expressed a decrease of the uterine implant number, followed by the preimplantation losses at all applied doses (1.22, 6.1, and 30.5mg/kg), and the number of embryonic resorptions in the two highest doses (6.1 and 30.5mg/kg). After the organ weighing (hypophysis, ovaries, and uterus), only the relative weight of the hypophysis was raised at the different doses (1.22, 6.1, and 30.5mg/kg). It was concluded that the hydroalcoholic extract of Pradosia huberi compromises the reproductive ability during the embryonic preimplantation phase, suggesting a possible toxic effect upon the reproductive system of Wistar rats. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 23146133
- Volume :
- 2013
- Database :
- Academic Search Index
- Journal :
- BioMed Research International
- Publication Type :
- Academic Journal
- Accession number :
- 100395053
- Full Text :
- https://doi.org/10.1155/2013/294172