Nitroxide-Mediated Polymerization of 2-(Diethylamino)ethylMethacrylate (DEAEMA) in Water.

Nitroxide-mediated polymerization(NMP) of 2-(diethylamino)ethylmethacrylate (DEAEMA) with a small amount of acrylonitrile (AN) asa comonomer was performed for the first time in water at 90 °Cand atmospheric pressure using n-hydroxysuccinimidylBlocBuilder (NHS-BB) alkoxyamine without addition of excess nitroxide.The same reaction was carried out using the bicomponent initiatingsystem composed of 2,2′-azobis[2-(2-imidazolin-2-yl)propane]dihydrochloride(VA-044) as initiator and N-tert-butyl-N-(1-diethylphosphono-2,2-dimethylpropyl)nitroxide (SG1) as nitroxide. Both polymerization reactions were well-controlledand exhibited excellent livingness as evidenced by low molar dispersityand evolution of the molar mass distribution. The hydrolytic stabilityof DEAEMA at the polymerization conditions and the effects of severalparameters including initiating system, temperature, ratio of nitroxideto initiator, initiator and monomer concentrations, and comonomertype were investigated. Chain extension of the synthesized macroinitiatorwith methyl methacrylate (MMA) and styrene (S) in a one-pot processled to the in situformation of poly(DEAEMA-co-S)-b-poly(MMA-co-S)diblock copolymers based on the polymerization-induced self-assembly(PISA) process. [ABSTRACT FROM AUTHOR]