C-REACTIVE PROTEIN (CRP); IN PATIENTS WITH METABOLIC SYNDROME.

Objective: To determine the frequency of raised C-reactive protein (CRP) in patients with metabolic syndrome. Patients and methods: This cross sectional descriptive study of six months study was conducted at Liaquat University Hospital Hyderabad. All the patients of 20 to 60 years of age, of either gender presented with symptoms of metabolic syndrome for more than 01 year duration were admitted and evaluated for C-reactive protein. The data was analyzed in SPSS 16 and the frequency and percentage was calculated. Results: Total one hundred patients (59 females and 41 males) with metabolic syndrome were evaluated for C-reactive protein. The mean waist circumference for males and female patients with raised CRP was 48.93±2.33 and 48.42±3.41 while the mean ±SD of serum triglycerides level for male and female with raised CRP was 192.41±3.21 and 196.31±3.43 respectively. The mean ±SD of serum HDL-C level for male and female with raised CRP was 28.32±1.22 and 25.31±1.42. The mean ±SD of systolic and diastolic pressure for males and female patients with raised CRP was 150±3.42 and 100.51±4.42. The mean ±SD of serum fasting blood sugar for male and female patients with raised CRP was 131.52±3.33 and 143.42±7.42 respectively. The mean ±SD of CRP for male and female patients with raised CRP was 4.42±1.21 and 5.8±2.52. In relation to gender distribution, the majority of subjects from 40-49 years of age group with female predominance (p = 0.01) while the CRP was raised in 67% patients in relation to age (p=0.05) and gender (p=0.04) respectively. Out of 67 subjects with raised CRP 44 were females and 23 were males. Conclusions: The CRP was raised in patients with metabolic syndrome. [ABSTRACT FROM AUTHOR]