Back to Search
Start Over
Wadsworth–Emmons reaction: the unique catalytic reaction by a solid base
- Source :
-
Journal of Catalysis . Aug2003, Vol. 218 Issue 1, p191. 10p. - Publication Year :
- 2003
-
Abstract
- The near-stoichiometric amount of bases is used both in laboratory and industry in Wadsworth–Emmons (WE) reactions, since the by-product, (EtO)2P(O)OH, formed in the reaction neutralizes the base into an inert salt. A strategy to design, develop, and evolve the recyclable Mg–Al–hydrotalcite–O <f>t</f>Bu (HT–O<f> t</f>Bu) by the interaction of KO<f> t</f>Bu with the calcined hydrotalcite that transforms a well-defined stoichiometric WE reaction into a catalytic one in an effort to minimize the quantum of effluents released and reduce the cost of the process is described here. HT–O<f> t</f>Bu is found to be an efficient solid base for WE reactions for the simple synthesis of <f>α,β</f>-unsaturated esters and nitriles for the first time. The HT–O<f> t</f>Bu, composed of various ratios of Mg<f>/</f>Al (i.e., 2, 2.5, and 3) and different contents of <f>t</f>BuO<f>−</f> (Mg<f>/</f>Al:3), and their precursors were prepared and well characterized to draw a correlation between structure and reactivity of the hydrotalcites in WE reactions. [Copyright &y& Elsevier]
- Subjects :
- *POTASSIUM
*SALT
Subjects
Details
- Language :
- English
- ISSN :
- 00219517
- Volume :
- 218
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Journal of Catalysis
- Publication Type :
- Academic Journal
- Accession number :
- 10064022
- Full Text :
- https://doi.org/10.1016/S0021-9517(03)00080-0