Enantioselective synthesis of 1,2,4-triazolines by chiral iron(ii)-complex catalyzed cyclization of α-isocyano esters and azodicarboxylates.

Enantioselective cyclization of α-isocyano esters with azodicarboxylates catalyzed by FeII–N,N′-dioxide complexes has been developed. Under mild conditions, a variety of 1,2,4-triazoline derivatives was obtained in high yields and enantioselectivities. [ABSTRACT FROM AUTHOR]