Asymmetric formation of tert-alkylamines from serinols by a dual function catalyst.

Consecutive intramolecular desymmetrization and kinetic resolution of 2-substituted N-phenoxycarbonylserinols have been achieved in one-pot by a single chiral catalyst, bisox(7)–CuCl2, to form oxazolidinones with remarkable enantioselectivities (94–99% ee) as tert-alkylamine building blocks. The process culminates in a dual-function of the chiral catalyst. [ABSTRACT FROM AUTHOR]