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Prefrontal cortex as a compensatory network in ataxic gait: A correlation study between cortical activity and gait parameters.
- Source :
-
Restorative Neurology & Neuroscience . 2015, Vol. 33 Issue 2, p177-187. 11p. - Publication Year :
- 2015
-
Abstract
- Purpose: To investigate whether prefrontal cortex (PFC) functioning during ataxic gait is linked to compensatory mechanisms or to the typical intra-subject variability of the ataxic gait. Methods: Nineteen patients with chronic ataxia and fifteen healthy subjects were evaluated. The subjects were requested to walk along a straight distance of 10 meters while PFC oxygenation and gait parameters were assessed. PFC activity was evaluated by NIRO-200 while gait analysis was performed by the SMART-D500. To investigate the intra-subject variability of gait, we calculated the coefficient of multiple correlation (CMC) of the hip, knee and ankle kinematic waveforms furthermore, we evaluated the step width. Results: We observed a positive correlation between PFC bilateral oxygenation changes and the step width (r = 0.54; p = 0.02 for the right PFC, and r = 0.50; p = 0.03 for the left PFC). No correlation was found between PFC activity and CMC of the hip, knee and ankle waveforms. Conclusions: Our results suggest that PFC activity is linked to gait compensatory mechanisms more than to the variability of the joint kinematic parameters caused by a defective cerebellar control. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09226028
- Volume :
- 33
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Restorative Neurology & Neuroscience
- Publication Type :
- Academic Journal
- Accession number :
- 101024970
- Full Text :
- https://doi.org/10.3233/RNN-140449