Hydrophobic monofunctionalized cucurbit[7]uril undergoes self-inclusion complexation and forms vesicle-type assemblies.

Hydrophobic monofunctionalized cucurbit[7]uril derivatives (1 and 2) were synthesized by clicking CB[7]-azide with propargylated alkylamines. Compounds 1 and 2 form self-inclusion complexes that are transformed into vesicle-type assemblies by addition of guests (3–5) as confirmed by 1H and DOSY NMR, SEM, TEM, and fluorescence spectroscopy. [ABSTRACT FROM AUTHOR]