Modified DTPA molecule-based nanocolloid radiopharmaceuticals.

The researches Tc recovery process at presence of divalent Sn(II) were made to determine necessary and sufficient amount of Sn(II), which would provide its full reducibleness in the reaction mixture. That the solution of Tc eluate reacts directly with the solution of modified DTPA and SnCl the content of radiochemical impurity (RCI) of the unreduced Tc(VII) in the labeled nanocolloid is 2.7 %, while the yield of the nanocolloid with the size of 100 nm is approximately 80 %. The results of researches prove the nanocolloid actively gets into the lymphatic system after injection, thus indicating its functional usefulness. [ABSTRACT FROM AUTHOR]