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Natural killer T cell strategies to combat Epstein–Barr virus infection.
- Source :
-
OncoImmunology . Apr2014, Vol. 3 Issue 4, pN.PAG-N.PAG. 1p. - Publication Year :
- 2014
-
Abstract
- Epstein–Barr virus (EBV) infection results in rapid loss of CD1d expression from the surface of infected B cells, thus enabling the virus to evade immune recognition by natural killer T (NKT) cells. Using pharmacologic means to boost CD1d expression, potent NKT cell effector functions can be elicited toward EBV-infected B cells, suggesting the promise of novel strategies to target EBV-associated diseases such as some B-cell malignancies. [ABSTRACT FROM PUBLISHER]
- Subjects :
- *CYTOTOXIC T cells
*VIRUS diseases
*IMMUNE recognition
*GENE expression
*B cells
Subjects
Details
- Language :
- English
- ISSN :
- 21624011
- Volume :
- 3
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- OncoImmunology
- Publication Type :
- Academic Journal
- Accession number :
- 101348077
- Full Text :
- https://doi.org/10.4161/onci.28329