Antioxidant and Antimicrobial Activities of Helinus lanceolatus.

The extracts of petroleum ether, chloroform, methanol and aqueous of Helinus lanceolatus were tested for their antioxidant potential, antibacterial and antifungal activities. The results revealed that the methanolic extract showed the highest zone of inhibition 50 ± 1.15 mm against Escherichia coli and aqueous extract shows excellent inhibition for fungi Aspergillus niger 17 ± 2.6 mm. The water extract showed highest DPPH radical scavenging activity i.e. 91.8 ± 0.0.09% at a concentration of 500 μg/ml with IC50 value 12.29 ± 0.59 μg/ml relative to butylated hydroxyltoluene (BHT) having IC50 value 12.52 ± 0.89 μg/ml. Chloroform extract showed highest antioxidant activity 0.840 ± 0.13 μg/ml relative to standard 0.891 ± 0.13 μg/ml while the highest FRAP value i.e. 90.66 ± 4.54 TE μg/ml was shown by petroleum ether fraction. Methanolic extract also showed good value of inhibition of lipid peroxidation, i.e. 59.11 ± 0.12%. [ABSTRACT FROM AUTHOR]