Polymorphism in gyrA is associated to quinolones resistance in Chilean Piscirickettsia salmonis field isolates.

The article discusses the use of quinolones as the antimicrobial compounds against salmonid rickettsial septicaemia (SRS) in Chile. It states that quinolones susceptibility was assessed in 20 P. salmonis isolates cultured from kidney samples of diseased fish collected from diverse geographic origin from 2010-2012. It mentions the hypothesis that Chilean quinolone-resistant P. salmonis isolates may have mutations on their Quinolone Resistance-Determining Region (QRDR).