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Total Synthesis of Laingolide A Diastereomers.

Authors :
Pomey, Gaétan
Phansavath, Phannarath
Source :
Synthesis. 2015, Vol. 47 Issue 7, p1016-1023. 8p.
Publication Year :
2015

Abstract

The first total syntheses of two (±)-laingolide A diastereomers were achieved in 11 and 12 steps, respectively. The key steps include a tandem cross-dimerization/oxonia-Cope reaction and an intramolecular dehydrative cyclization for the formation of either the transor cis-enamide moieties. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00397881
Volume :
47
Issue :
7
Database :
Academic Search Index
Journal :
Synthesis
Publication Type :
Academic Journal
Accession number :
101664168
Full Text :
https://doi.org/10.1055/s-0034-1380133