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Quantum chemical studies on newly synthesized tin anticancer compounds

Authors :
Chojnacki, Henryk
Source :
Journal of Molecular Structure: THEOCHEM. Jul2003, Vol. 630 Issue 1-3, p291. 5p.
Publication Year :
2003

Abstract

The electronic structure of newly synthesized tin anticancer complexes coordinating one, two and four tin atoms has been studied both at semiempirical level and by using ab initio methods at the correlation level. The most probable structures of the systems under consideration have been determined being in a good agreement with the relevant experimental results. The compounds show very effective antitumor cytotoxic activity against A549 and HSMC cells. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
01661280
Volume :
630
Issue :
1-3
Database :
Academic Search Index
Journal :
Journal of Molecular Structure: THEOCHEM
Publication Type :
Academic Journal
Accession number :
10178082
Full Text :
https://doi.org/10.1016/S0166-1280(03)00158-1