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GPOPSIM: a simulation tool for whole-genome genetic data.
- Source :
-
BMC Genetics . 2015, Vol. 16 Issue 1, p1-6. 6p. - Publication Year :
- 2015
-
Abstract
- Background: Population-wide genotypic and phenotypic data is frequently used to predict the disease risk or genetic/phenotypic values, or to localize genetic variations responsible for complex traits. GPOPSIM is a simulation tool for pedigree, phenotypes, and genomic data, with a variety of population and genome structures and trait genetic architectures. It provides flexible parameter settings for a wide discipline of users, especially can simulate multiple genetically correlated traits with desired genetic parameters and underlying genetic architectures. Results: The model implemented in GPOPSIM is presented, and the code has been made freely available to the community. Data simulated by GPOPSIM is a good mimic to the real data in terms of genome structure and trait underlying genetic architecture. Conclusions: GPOPSIM would be a useful tool for the methodological and theoretical studies in the population and quantitative genetics and breeding. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 14712156
- Volume :
- 16
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- BMC Genetics
- Publication Type :
- Academic Journal
- Accession number :
- 101976571
- Full Text :
- https://doi.org/10.1186/s12863-015-0173-4