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Can SLE be treated by altering T-cell metabolism?

Authors :
Bernard, Nicholas J.
Source :
Nature Reviews Rheumatology. Apr2015, Vol. 11 Issue 4, p197-197. 1/2p.
Publication Year :
2015

Abstract

The article discusses a research paper on the use of normalization of CD4 T cell metabolism for the treatment of lupus. It references the study "Normalization of CD4 T Cell Metabolism Reverses Lupus," published by Y. Yin et al., published in an issue of "Science Translational Medicine." It discusses the dependence of T-cell function on cellular metabolism, the response of polyclonal stimulation in vitro and findings on the extracellular acidification rate and oxygen consumption rate.

Details

Language :
English
ISSN :
17594790
Volume :
11
Issue :
4
Database :
Academic Search Index
Journal :
Nature Reviews Rheumatology
Publication Type :
Academic Journal
Accession number :
102069618
Full Text :
https://doi.org/10.1038/nrrheum.2015.24