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Copper-Catalyzed Trifluoromethylation of Trisubstituted Allylic and Homoallylic Alcohols.
- Source :
-
Chemistry - A European Journal . Apr2015, Vol. 21 Issue 18, p6700-6703. 4p. - Publication Year :
- 2015
-
Abstract
- An efficient copper-catalyzed trifluoromethylation of trisubstituted allylic and homoallylic alcohols with Togni's reagent has been developed. This strategy, accompanied by a double-bond migration, leads to various branched CF3-substituted alcohols by using readily available trisubstituted cyclic/acyclic alcohols as substrates. Moreover, for alcohols in which β-H elimination is prohibited, CF3-containing oxetanes are isolated as the sole product. [ABSTRACT FROM AUTHOR]
- Subjects :
- *COPPER catalysts
*ALLYL alcohol
*TRIFLUOROMETHYL compounds
*ALLYLSILANES
*ALKENES
Subjects
Details
- Language :
- English
- ISSN :
- 09476539
- Volume :
- 21
- Issue :
- 18
- Database :
- Academic Search Index
- Journal :
- Chemistry - A European Journal
- Publication Type :
- Academic Journal
- Accession number :
- 102122297
- Full Text :
- https://doi.org/10.1002/chem.201406627