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Targeted Disruption of Aldh1a1 (Raldh1) Provides Evidence for a Complex Mechanism of Retinoic Acid Synthesis in the Developing Retina.

Authors :
Xiaohong Fan
Molotkov, Andrei
Manabe, Shin-Ichi
Donmoyer, Christine M.
Deltour, Louise
Foglio, Mario H.
Cuenca, Arnold E.
Blaner, William S.
Lipton, Stuart A.
Duester, Gregg
Source :
Molecular & Cellular Biology. Jul2003, Vol. 23 Issue 13, p4637. 12p. 26 Black and White Photographs, 3 Diagrams, 1 Chart, 7 Graphs.
Publication Year :
2003

Abstract

Provides evidence for a complex mechanism of retinoic acid (RA) synthesis in the developing retina. Examination of the function of related gene Aldh1a1; Detection of RA signaling in the optic cup; Use of retrograde labeling and electroretinography.

Subjects

Subjects :
*TRETINOIN
*RETINA

Details

Language :
English
ISSN :
02707306
Volume :
23
Issue :
13
Database :
Academic Search Index
Journal :
Molecular & Cellular Biology
Publication Type :
Academic Journal
Accession number :
10216054
Full Text :
https://doi.org/10.1128/MCB.23.13.4637-4648.2003