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Targeting dengue virus NS4B protein for drug discovery.
- Source :
-
Antiviral Research . Jun2015, Vol. 118, p39-45. 7p. - Publication Year :
- 2015
-
Abstract
- The flavivirus nonstructural 4B protein (NS4B) has recently emerged as a valid antiviral target for drug discovery. Here we review (i) the current understanding of the structure and function of DENV NS4B, (ii) the approaches that have been taken to identify NS4B inhibitors, and (iii) the known inhibitors of flavivirus NS4B protein. This article forms part of a symposium in Antiviral Research on flavivirus drug discovery. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 01663542
- Volume :
- 118
- Database :
- Academic Search Index
- Journal :
- Antiviral Research
- Publication Type :
- Academic Journal
- Accession number :
- 102312078
- Full Text :
- https://doi.org/10.1016/j.antiviral.2015.03.007