Progress in Controlled Ovarian Stimulation Protocols of Polycystic Ovary Syndrome.

Polycystic ovary syndrome (PCOS),a common clinical endocrine disorder, is the main cause of anovulatory infertility in women of childbearing age. Due to the particular endocrine disorders in PCOS patients, it is hard to predict ovarian responses to drugs during controlled ovarian stimulation (COS). So, poor ovarian responses and ovarian hyperstimulation syndrome (OHSS) are incredibly common. The common protocols used in IVF for PCOS patients include long protocol, antagonist protocol, mild stimulation protocol, revised super-long protocol, super-long protocol and in vitro maturation (IVM). Presently, long protocol is most frequently used in most of reproductive centers. At the same time, antagonist protocol and mild stimulation protocol, as new protocols, are gradually favored by many clinicians. Super-long protocol and the revised super-long protocol, as the improved traditional protocols, have also obtained good clinic results. IVM,as a technical innovation, can simplify treatment and reduce the risk of OHSS. During IVF for patients with PCOS,it is the key point for clinicians to choose the optimal and economical treatment, to get high -quality eggs and embryos, and to avoid complications such as OHSS. [ABSTRACT FROM AUTHOR]