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Study of cardiovascular disease biomarkers among tobacco consumers. Part 3: evaluation and comparison with the US National Health and Nutrition Examination Survey.
- Source :
-
Inhalation Toxicology . Feb2015, Vol. 27 Issue 3, p167-173. 7p. - Publication Year :
- 2015
-
Abstract
- Cardiovascular disease (CVD) biomarkers of biological effect (BoBE), including hematologic biomarkers, serum lipid-related biomarkers, other serum BoBE, and one physiological biomarker, were evaluated in adult cigarette smokers (SMK), smokeless tobacco consumers (STC), and non-consumers of tobacco (NTC). Data from adult males and females in the US National Health and Nutrition Examination Survey and a single site, cross-sectional study of healthy US males were analyzed and compared. Within normal clinical reference ranges, statistically significant differences were observed consistently for fibrinogen, C-reactive protein (CRP), hematocrit, mean cell volume, mean cell hemoglobin, hemoglobin, white blood cells, monocytes, lymphocytes, and neutrophils in comparisons between SMK and NTC; for CRP, white blood cells, monocytes, and lymphocytes in comparisons between SMK and STC; and for folate in comparisons with STC and NTC. Results provide evidence for differences in CVD BoBE associated with the use of different tobacco products, and provide evidence of a risk continuum among tobacco products and support for the concept of tobacco harm reduction. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 08958378
- Volume :
- 27
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Inhalation Toxicology
- Publication Type :
- Academic Journal
- Accession number :
- 102644666
- Full Text :
- https://doi.org/10.3109/08958378.2015.1009196