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Assessment and Research to Applying Prone Position Ventilation Oxygenation and Circulation to Acute Exacerbation of Chronic Obstructive Pulmonary Disease Patients in Pro-Intrusive Ventilation Phase.
- Source :
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Journal of Kunming Medical University / Kunming Yike Daxue Xuebao . 2015, Vol. 36 Issue 5, p42-48. 7p. - Publication Year :
- 2015
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Abstract
- Objective To investigate the improvement of oxygenation, hemodynamics, extubation time and time in ICU of patients of AECOPD in their Pro-Intrusive Ventilation Phase, as well as to evaluate the overall treatment effectiveness of Prone Position Ventilation to AECOPD patients; and to hopefully provide advices to the application of Prone Position Ventilation as a clinic practice. Method 80 pro-intrusive ventilation patients with AECOPD were evenly and randomly divided into two groups: forty patients each in experimental and control groups. Patients in both experimental and control groups are treated strictly according to The Treatment Guideline to Chronic Obstructive Lung Diseases China 2011 Edition), while patients in experimental group were given treatment of Prone Position Ventilation PPV). Central venous pressure CVP), heart rate HR), mean arterial pressure MAP), cardiac output CO), cardiac index CI), stroke volume SV) and stroke volume variation rate SVV) monitoring, oxygen saturation SpO2), blood oxygen pressure PaO2), oxygenation index PaO2/FiO2) of the all patients in both groups were recorded before hospitalization and 1 hour, 8 hours, 24 hours. Their oxygen saturation SpO2, blood oxygen pressure PaO2), oxygenation index PaO2/FiO2), chest CT changes were also recorded 1 day, 7 days, 14 days after PPV, and their duration in ICU and days of hospitalization, patients' age, frequency of hospitalization, FEV1 and APACHE II evaluations were also compared. Results (1) Comparison of blood and oxygenation monitoring: arterial oxygen tension PaO2, oxygen saturation SpO2, oxygenation index PaO2FiO2 were improved in 1 hour; while oxygen saturation SpO2), oxygenation index PaO2/ FiO2) in 8 and 24 hours of the experimental group were higher than those of control groups with statistic significance P < 0.05) ; arterial oxygen tension PaO2), oxygen saturation SpO2, oxygenation index PaO2FiO2 were improved from day 1, while the oxygen saturation SpO2 and oxygenation index PaO2FiO2 of the experimental group were higher than those of control groups with statistic significance P < 0.005) . (2) Comparison of hemodynamics: the HR, MBP, CVP, CO, CI, SV, SVV of both experimental and control groups in 1, 8, and 24 hours had no statistically significant difference P > 0.05). (3) Extubation time and ICU stay-time: there is a statistically significant difference in extubation time between experimental and control groups: the median extubation time of the experimental groups 19.04) days: control group 20.83) days; there is also statistically significant difference in ICU stay-time between experimental and control groups: the median ICU stay-time of the experimental groups 8.85) days: control group 10.46) days P<0.05). Conclusion Comparing to Spine Position Ventilation, Prone Position Ventilation remarkably improves the oxygenation, reduces the extubation time and decreases the ICU stay-time of the patients with AECOPD in their pro-intrusive positive pressure ventilation phase; while PPV does not show influence on hemodynamics changes. [ABSTRACT FROM AUTHOR]
Details
- Language :
- Chinese
- ISSN :
- 2095610X
- Volume :
- 36
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Journal of Kunming Medical University / Kunming Yike Daxue Xuebao
- Publication Type :
- Academic Journal
- Accession number :
- 102746610