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A Case of Familial Carney Complex.
- Source :
-
Archives of Iranian Medicine (AIM) . May2015, Vol. 18 Issue 5, p324-328. 5p. - Publication Year :
- 2015
-
Abstract
- Carney complex is a syndrome characterized by skin pigmentation abnormalities, myxomas, endocrine tumors/overactivity, and schwannomas. It is caused by a mutation in the PRKAR1A gene that encodes the enzyme protein kinase A regulatory subunit type 1 alpha. A 23-year old male was diagnosed with Carney complex on the basis of spotty skin lentigines on his face and lips, multiple thyroid neoplasms, a right ventricular myxoma, and bilateral testicular tumors. A total bilateral orchectomy was performed and the pathological findings revealed Leydig's cell tumors on one side and a Sertoli cell tumor on the other side. When his first-degree relatives were examined, his mother was found to have Carney complex as well. This is the first reported case of familial Carney complex in China. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10292977
- Volume :
- 18
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Archives of Iranian Medicine (AIM)
- Publication Type :
- Academic Journal
- Accession number :
- 102755212