Determination of Lantadene A Contents in the Crude Extracts from Stems, Leaves and Fruits of Lantana camara L. and Their Antibacterial Activities.

[Objective] To find new plant source having antibacterial activities to Staphylococcus aureus. [Methods] Lantadene A (LA) was isolated and identified from Lantana camara L.; the structure of LA was identified by H NMR spectrum. With LA as the standard substance, the LA contents in the stems, leaves and fruits of L. camara were detected by UV spectrophotometry; and antibacterial test was carried out by disc agar diffusion. [Results] LA contents in the dry powders of L. camara stems, leaves and fruits were 1.49, 3.43 and 2.74 mg/g, respectively. Results of antibacterial test showed that the crude extracts from L. camara stems, leaves and fruits had certain bacteriostatic activitives to S. aureus. And bacteriostatic activities had positive correlation with the LA content. [Conclusions] Lantadene A isolated from L. camara had certain inhibitory effects on S. aureus, which was worthy of further research. [ABSTRACT FROM AUTHOR]