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Treatment of Hepatitis C in HIV-Infected Patients: Moving Towards an Era of All Oral Regimens.
- Source :
-
AIDS Patient Care & STDs . Jun2015, Vol. 29 Issue 6, p329-337. 9p. 2 Charts. - Publication Year :
- 2015
-
Abstract
- Hepatitis C (HCV)-related liver disease has become one of the leading causes of death in HIV patients. With the development of new direct-acting antivirals for HCV, treatment regimens have become shorter, more effective, and easier to tolerate without interferon. However, cost may be a significant impediment to the widespread use of these newer agents in both resource-rich and resource-poor settings. In HIV patients, treatment for HCV is not always as straightforward compared with HCV monoinfected patients due to potential drug-drug interactions. In this article, we will examine by genotypes the FDA approved direct-acting antivirals, as well as those in clinical trials that will soon be FDA-approved focusing on data in HCV/HIV co-infection. Preferred agents for HCV treatment and potential drug-drug interactions with antiretroviral therapy (ART) will be highlighted. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10872914
- Volume :
- 29
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- AIDS Patient Care & STDs
- Publication Type :
- Academic Journal
- Accession number :
- 102915308
- Full Text :
- https://doi.org/10.1089/apc.2014.0247