Bioactive carbazole alkaloids from the stems of Clausena lansium.

Seven new carbazole alkaloids, claulansines L-R ( 1 – 7 ), and six known analogues ( 8 – 13 ) were isolated from the stems of Clausena lansium . Their structures were elucidated on the basis of spectroscopic analyses, including UV, IR, and NMR experiments (HSQC, HMBC, and NOE experiment). Compound 7 showed moderate anti-inflammatory activities. Compounds 3 , 5 , 6 , 8 , and 12 exhibited moderate hepatoprotective activities. [ABSTRACT FROM AUTHOR]