Case of neuroleptic malignant syndrome with diffuse neurofibrillary tangles with calcification.

The article presents a case study of a 75-year-old man with dementia who was referred to Tsuruga Onsen Hospital. He experienced memory impairment followed by utilization behavior, stereotypy, pyramidal signs, gait disorders, and personality change. He received tiapride and risperidone for his irritability, and aggression wherein he developed neuroleptic malignant syndrome (NMS). The patient was diagnosed with NMS with diffuse neurofibrillary tangles with calcification (DNTC).