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Weak D Type 4.2.2 (DAR1.2) in an African child: Serology and molecular characterization.
Weak D Type 4.2.2 (DAR1.2) in an African child: Serology and molecular characterization.
- Source :
-
Transfusion & Apheresis Science . Apr2015, Vol. 52 Issue 2, p217-219. 3p. - Publication Year :
- 2015
-
Abstract
- The weak D phenotype is represented by a group of RHD genotypes that code for alterated RhD proteins associated with a reduced RhD expression on red blood cell. By routine serology, some partial D variants are likely to be missed. In this report we describe the case of a three-year-old Black African child with a “unclear” reaction with monoclonal anti-D. We analyzed the blood sample of the child with different methods to conclude that it is a case of DAR 1.2 (weak D 4.2.2) and that it must be transfused with D negative erithrocytes. [ABSTRACT FROM AUTHOR]
- Subjects :
- *RABBIT calicivirus disease
*SEROLOGY
*GENOTYPES
*ERYTHROCYTES
*GENE expression
Subjects
Details
- Language :
- English
- ISSN :
- 14730502
- Volume :
- 52
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Transfusion & Apheresis Science
- Publication Type :
- Academic Journal
- Accession number :
- 103055107
- Full Text :
- https://doi.org/10.1016/j.transci.2014.12.020