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Laboratory confirmation of clinically diagnosed malaria in a cohort of HIV-infected mothers and their children in Malawi.
- Source :
-
Journal of Tropical Pediatrics . Jun2015, Vol. 61 Issue 3, p222-225. 4p. - Publication Year :
- 2015
-
Abstract
- To avoid overdiagnosis, accuracy in the identification of true malaria cases is of critical importance. Samples (either whole blood, dried blood spots or plasma/serum) collected at the time of clinically diagnosed malaria episodes in a cohort of Malawian HIV-infected mothers and their children were retrospectively tested with the enzyme-linked immunosorbent assay (ELISA) for HRP-2 (histidine- rich protein 2) detection. There were 55 and 56 clinically diagnosed cases of malaria in mothers and children, respectively, with samples available for testing. Rates of laboratory-confirmed episodes were 20% (11 of 55) in mothers and 16.1% (9 of 56) in children. Hemoglobin was lower in children with confirmed malaria compared to those with clinical malaria diagnosis. The results of our study support the widespread use of rapid diagnostic tests. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 01426338
- Volume :
- 61
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Journal of Tropical Pediatrics
- Publication Type :
- Academic Journal
- Accession number :
- 103291608
- Full Text :
- https://doi.org/10.1093/tropej/fmv011