Kinetic Study on Alkaline Hydrolysis of Y-substituted Phenyl Picolinates: Effects of Modification of Nonleaving Group from Benzoyl to Picolinyl on Reactivity and Reaction Mechanism.

Second-order rate constants ( kOH-) for alkaline hydrolysis of Y-substituted phenyl picolinates ( 6a-6i) have been measured spectrophotometrically. A linear Brønsted-type plot is obtained with βlg = −0.34, which is typical for reactions reported previously to proceed through a stepwise mechanism with formation of an addition intermediate being the rate-determining step ( RDS). However [ABSTRACT FROM AUTHOR]