Microwave-promoted direct amidation of unactivated esters catalyzed by heteropolyanion-based ionic liquids under solvent-free conditions.

Authors :: Fu, Renzhong
Yang, Yang
Ma, Yunsheng
Yang, Fei
Li, Jingjing
Chai, Wen
Wang, Quan
Yuan, Rongxin
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Jul2015, Vol. 56 Issue 30, p4527-4531. 5p.
Publication Year :: 2015
Abstract: A simple and efficient procedure for the synthesis of amides directly from unactivated esters and amines catalyzed by heteropolyanion-based ionic liquids under microwave-promoted and solvent-free conditions has been reported. The practical protocol was found to be compatible with different structurally diverse substrates. Moderate to excellent yields, solvent-free media, and operational simplicity are the main highlights. Furthermore, the heteropolyanion-based ionic liquids were easily reusable for this amidation. [ABSTRACT FROM AUTHOR]

Subjects :: *MICROWAVES
*ESTERS analysis
*AMIDATION
*POLYANIONS
*IONIC liquids
*SOLVENT analysis

Language :: English
ISSN :: 00404039
Volume :: 56
Issue :: 30
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 103424685
Full Text :: https://doi.org/10.1016/j.tetlet.2015.05.118

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