Back to Search
Start Over
Recent Advances in Elucidating the Genetic Mechanisms of Nephrogenesis Using Zebrafish.
- Source :
-
Cells (2073-4409) . 2015, Vol. 4 Issue 2, p218-233. 16p. - Publication Year :
- 2015
-
Abstract
- The kidney is comprised of working units known as nephrons, which are epithelial tubules that contain a series of specialized cell types organized into a precise pattern of functionally distinct segment domains. There is a limited understanding of the genetic mechanisms that establish these discrete nephron cell types during renal development. The zebrafish embryonic kidney serves as a simplified yet conserved vertebrate model to delineate how nephron segments are patterned from renal progenitors. Here, we provide a concise review of recent advances in this emerging field, and discuss how continued research using zebrafish genetics can be applied to gain insights about nephrogenesis. [ABSTRACT FROM AUTHOR]
- Subjects :
- *ZEBRA danio
*NEPHRONS
*KIDNEY development
*PROGENITOR cells
*VERTEBRATES
Subjects
Details
- Language :
- English
- ISSN :
- 20734409
- Volume :
- 4
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Cells (2073-4409)
- Publication Type :
- Academic Journal
- Accession number :
- 103456290
- Full Text :
- https://doi.org/10.3390/cells4020218