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Adenovirus Tales: From the Cell Surface to the Nuclear Pore Complex.

Authors :
Kremer, Eric J.
Nemerow, Glen R.
Source :
PLoS Pathogens. Jun2015, Vol. 11 Issue 6, p1-8. 8p.
Publication Year :
2015

Abstract

The article discusses the benefits of better understanding cell entry variations to control adenovirus (AdV) pathogenesis and vector tropism for gene therapy. Topics covered include the innate immune pattern recognition receptors (PRR), the cellular determinants dictating AdV tropism, and the use of the coxsackievirus and adenovirus receptor (CAR).

Subjects

Subjects :
*ADENOVIRUSES
*GENE therapy
*PATTERN recognition systems
*TROPISMS
*COXSACKIEVIRUSES

Details

Language :
English
ISSN :
15537366
Volume :
11
Issue :
6
Database :
Academic Search Index
Journal :
PLoS Pathogens
Publication Type :
Academic Journal
Accession number :
103565339
Full Text :
https://doi.org/10.1371/journal.ppat.1004821
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