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Distinct Mechanisms for Regulating the Tumor Suppressor and Antiapoptotic Functions of Rb.
- Source :
-
Journal of Biological Chemistry . 5/23/2003, Vol. 278 Issue 21, p19358. 9p. 12 Color Photographs, 11 Black and White Photographs, 3 Diagrams, 38 Graphs. - Publication Year :
- 2003
-
Abstract
- Investigates the distinct mechanisms for the regulation of the tumor suppressor and antiapoptotic functions of the retinoblastoma protein (Rb). Immunoprecipitations and in vitro phosphorylation; Hyperphosphorylation and inactivation of ectopic Rb; Regulation of Rb apoptotic activity.
- Subjects :
- *TUMOR suppressor proteins
*PROTEINS
*BIOCHEMISTRY
Subjects
Details
- Language :
- English
- ISSN :
- 00219258
- Volume :
- 278
- Issue :
- 21
- Database :
- Academic Search Index
- Journal :
- Journal of Biological Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 10394405
- Full Text :
- https://doi.org/10.1074/jbc.M301761200