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Nuclear Localization of the Cell Cycle Regulator CDH1 and Its Regulation by Phosphorylation.

Authors :
Yuan Zhou
Yick-Pang Ching
Chun, Abel C.S.
Dong-Yan Jin
Source :
Journal of Biological Chemistry. 4/4/2003, Vol. 278 Issue 14, p12530. 7p. 13 Color Photographs, 39 Black and White Photographs, 1 Diagram, 2 Graphs.
Publication Year :
2003

Abstract

Examines the nuclear localization of the cell cycle regulator CDH1 and its regulation by phosphorylation. Anaphase-promoting complex activated by CD20 and CDH1; reduction in the steady-state amount of cyclin A; CDH1-4D mutant mimicking the hyperphosphorylated form in the cytoplasm; Motion that phosphorylation inhibits nuclear import .

Subjects

Subjects :
*CELL cycle
*PHOSPHORYLATION

Details

Language :
English
ISSN :
00219258
Volume :
278
Issue :
14
Database :
Academic Search Index
Journal :
Journal of Biological Chemistry
Publication Type :
Academic Journal
Accession number :
10394438
Full Text :
https://doi.org/10.1074/jbc.M212853200