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Werner syndrome protein limits MYC-induced cellular senescene.
- Source :
-
Genes & Development . 7/1/2003, Vol. 17 Issue 13, p1569. 6p. 2 Color Photographs, 6 Black and White Photographs, 1 Diagram. - Publication Year :
- 2003
-
Abstract
- Presents a study which proposed that the human Werner syndrome gene up-regulation by the MYC oncoprotein may promote MYC-driven tumorgenesis by preventing cellular senescence. Description of the MYC oncoprotein; Capabilities of MYC overexpression; Cause of the occurrence of rapid cellular senescence.
Details
- Language :
- English
- ISSN :
- 08909369
- Volume :
- 17
- Issue :
- 13
- Database :
- Academic Search Index
- Journal :
- Genes & Development
- Publication Type :
- Academic Journal
- Accession number :
- 10431009
- Full Text :
- https://doi.org/10.1101/gad.1100303