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Serological markers for leishmania donovani infection in Nepal: Agreement between direct agglutination test and rK39 ELISA.
- Source :
-
Tropical Medicine & International Health . Nov2010, Vol. 15 Issue 11, p1390-1394. 5p. - Publication Year :
- 2010
-
Abstract
- Visceral leishmaniasis (VL) is an important vector-borne disease caused by Leishmania donovani in the Indian subcontinent. The actual incidence and role of asymptomatic infections in the region are not wellknown. We used the direct agglutination test (DAT) and the rK39 ELISA as L. donovani infection markers in 10 VL endemic villages in Nepal. DAT titre distribution showed two subgroups in the population (infected and non-infected individuals), while rK39 did not. The agreement between both tests was moderate (j = 0.53; 95% CI 0.49–0.57). More research is needed to develop validated markers for Leishmania infection. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 13602276
- Volume :
- 15
- Issue :
- 11
- Database :
- Academic Search Index
- Journal :
- Tropical Medicine & International Health
- Publication Type :
- Academic Journal
- Accession number :
- 104636530
- Full Text :
- https://doi.org/10.1111/j.1365-3156.2010.02631.x