DEC1 Negatively Regulates the Expression of DEC2 through Binding to the E-box in the Proximal Promoter.

Authors :: Yuxin Li
Mingxin Xie
Xiulong Song
Gragen, Sarah
Sachdeva, Karuna
Yinsheng Wan
Bingfang Yan
Source :: Journal of Biological Chemistry. 5/9/2003, Vol. 278 Issue 19, p16899. 9p. 2 Diagrams, 13 Graphs.
Publication Year :: 2003
Abstract: Determines whether differentially expressed in chondrocytes (DEC)1 and DEC2 displayed similar expression patterns among paired tumor-normal tissues from the colon, lung, and kidney. Tissue collection and processing; Site-directed mutagenesis; Evidence that forced expression of DEC1 proportionally decreases the expression of DEC2.

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